Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep632 | Endocrine tumours and neoplasia | ECE2016

Evaluation of the incidence and clinical characteristics of glucose metabolism alterations during the follow-up of surgically treated insulinomas

Sergio Neves Joao , Lau Eva , Oliveira Joana , Isabel Oliveira Ana , Freitas Paula , Carvalho Davide

Introduction: The incidence of glucose metabolism alterations during the follow-up of surgically treated insulinomas is largely unknown. Our aim was to evaluate the incidence, and the clinical characteristics, of diabetes and prediabetes in this population.Methods: We retrospectively analyzed the cases diagnosed as insulinomas in a Central Hospital in Portugal in the period between January 1980 and December 2015.Results: We identif...

ea0040p16 | (1) | ESEBEC2016

Insulinomas at São João Hospital between 1980 and 2015

Neves Joao Sergio , Lau Eva , Oliveira Joana , Oliveira Ana Isabel , Freitas Paula , Carvalho Davide

Introduction: Insulinomas are pancreatic endocrine tumors originating in the beta cells, characterized by hypoglycemia resulting from insulin hypersecretion.Objectives: To characterize the demography, the clinical features, imagiological findings and pathological evaluation of the cases of insulinomas identified in the previous 35 years at São João Hospital.Methods: We retrospectively analyzed the cases diagnosed as insul...

ea0037ep641 | Obesity and cardiovascular endocrinology | ECE2015

Body composition in HIV-infected patients under combined antiretroviral therapy over 5 years

Grenha Ines , Oliveira Joana , Lau Eva , Vieira Romana , Serrao Rosario , Sarmento Antonio , Carvalho Davide , Freitas Paula

Introduction: HIV infection and combined antiretroviral therapy (cART) have been associated with lipodistrophy and changes in body composition. However, there are few studies on body composition evolution of HIV-infected patients, under cART.Aims: To evaluate the evolution of body composition in HIV-1 infected patients under cART over 5 years.Methods: Retrospective, observational study in a cohort of HIV-infected patients on cART. ...

ea0037ep724 | Pituitary: clinical | ECE2015

Serum cortisol in the early postoperative period as predictor of remission in Cushing's disease

Oliveira Joana , Lau Eva , Belo Sandra , Freitas Paula , Vinha Eduardo , Pereira Josue , Castro Ligia , Carvalho Davide

Introduction: Pituitary surgery is currently considered the preferred treatment for Cushing’s disease (CD) and achieves remission in 55–85% of patients. Cortisol falls quickly after surgery, so that early post-operative cortisol level has been used as predictor of remission. There’s no agreement about optimal timing for cortisol measurement, with wide variability between centres.Objective: To assess the value of early post-operative serum ...

ea0037ep725 | Pituitary: clinical | ECE2015

Predictive factors for remission and recurrence in Cushing's disease: a single-centre study

Oliveira Joana , Lau Eva , Belo Sandra , Freitas Paula , Vinha Eduardo , Pereira Josue , Castro Ligia , Carvalho Davide

Introduction: Cushing’s disease (CD) is characterised by pathologic hypercortisolism caused by an ACTH-secreting pituitary adenoma. The primary modality for definitive treatment is pituitary surgery. The rarity of CD has made it difficult to establish reliable predictive factors of outcomes.Aim: Assessment of clinical, hormonal, radiological, surgical and histological findings as predictors of remission and relapse of CD.Metho...

ea0037ep1243 | Clinical Cases–Pituitary/Adrenal | ECE2015

Acromegaly caused by atypical pituitary adenoma

Costa Maria Manuel , Saavedra Ana , Castro Ligia , Basto Margarida , Pereira Josue , Vinha Eduardo , Carvalho Davide

Introduction: Atypical pituitary adenomas have higher risk of aggressive behaviour in particular by the higher growth, local invasion and high risk of recurrence after surgery. In acromegaly the resistance to somatostatin analogues may be another manifestation of these adenomas since higher levels of Ki-67 are associated with poor response to therapy.Case report: A 41-year-old woman presented to our consult with history of headaches, growth of the hands,...

ea0037ep1299 | Clinical Cases–Thyroid/Other | ECE2015

Graves' orbitopathy coursing with hypothyroidism: a case-report

Saavedra Ana , Nunes Joana Menezes , Rodrigues Elisabete , Ribeiro Sara , Leal Victor , Carvalho Davide

Introduction: Graves’ orbitopathy is usually associated with Graves’ Disease, which is typically characterized by hyperthyroidism and goiter. However, in rare situations, Graves’ disease can also present with hypothyroidism and orbitopathy.Case report: Male, 38 years old, followed by his ophthalmologist for thyroid orbitopathy (exophthalmos right>left and conjunctival hyperaemia since 1 year ago) associated with asthenia, tiredness and...

ea0035p17 | Adrenal cortex | ECE2014

Female to male gender identity disorder in a patient with non-classical congenital adrenal hyperplasia

Lau Eva , Castedo Jose Luis , Rodrigues Pedro , Figueiredo Zelia , Carvalho Davide

Introduction: Congenital adrenal hyperplasia (CAH) is a prevalent disturb in female to male gender identity disorder (GID). However, psychoendocrinology of GID is not yet fully understood.Case Report: A 22-year-old patient(46, XX), was sent from Psychiatry-Sexology to Endocrinology consultation for GID to start hormonal treatment. Self-awareness as a male began at 12-year-old. Menarche at the age of 13 years. At 14-year-old, it was noticed overgrowth of ...

ea0035p311 | Clinical case reports Thyroid/Others | ECE2014

A rare case of cutaneous metastization of a differentiated thyroid carcinoma initially diagnosed as Hurthle cell adenoma

Castedo Jose-Luis , Costa Maria Manuel , Pimenta Tiago , Pestana-Silva Roberto , Carvalho Davide

Introduction: Cutaneous metastization of differentiated thyroid carcinomas is a rare event.Clinical case: MMS, a 69-year-old male was submitted to left hemithyroidectomy+isthmectomy on May 2006 after FNA of a left node revealed follicular tumor. Histology showed Hurthle cell adenoma. The patient maintained irregular follow-up by endocrinologist. In October 2011 he referred the appearance of small bilateral cervical skin nodules. Physical exam showed thre...

ea0035p389 | Diabetes (epidemiology, pathophysiology) | ECE2014

Characterization of severe hypoglycemia episodes evaluated in the emergency department of a central hospital

Esteves Cesar , Neves Manuel Celestino , Baldaia Rui , Sa Joao , Carvalho Davide

Introduction: Hypoglycemia is a major limiting factor in intensive glucose control in diabetes mellitus. Its incidence has been increasing with the demand for intensive therapy for the prevention of the diabetic chronic complications. There are few studies in our country regarding the evaluation of hypoglycemia in the emergency room (ER).Objective: To characterize severe hypoglycemia episodes and patient features in individuals admitted to the ER.<p ...