Endocrine Abstracts

Introduction: Hypothyroidism is known for its adverse effects for both the pregnant woman and her offspring. Our aim is to highlight the benefits of screening for hypothyroidism in all pregnant women with and without risk factors.Patients and methods: Prospective study, on 270 pregnant women. Women with disrupted thyroid balance, who smoke (active smoking confessed) and those followed for thyroid disease or taking medications that interfere with the thyr...

Introduction: Sensitive neuropathy is a degenerative complication of diabetes, precipitated by chronic glycemic imbalance. It is estimated that it is present in 50% of diabetics, and that it requires treatment in 10 to 20% of cases.This study aimedto assess the prevalence of sensitive neuropathy and to identify the factors associated with it in a population of patients with diabetes.Patients and Methods: This is a descriptive and a...

Aims: To assess the knowledge of diabetic patients on the health of their feetand to identify the associated factors with good knowledge, while providing podiatric advice.Methodology: It was a descriptive and analytical transversal prospective studyabout 100 diabetic patients (44 men, 56 women; age range 29–87 years). They had an evaluation of their knowledge on the diabetic foot, using a pre-established questionnaire as well as a metabolic evaluat...

Introduction: The American Diabetes Association (ADA) recommends an annual foot screening of patients podiatric risk for ulceration and amputation, to take effective preventive measures. However, the gradation of the podiatric risk remains insufficient, particularly in Tunisia, where epidemiological references remain missing. The aim of this study was to classify a population of diabetic patients according to the grade of podiatric risk by referring to the recommendations of t...

Objectives: Patients with metabolic syndrome who presents with vascular, metabolic or bone disorders of recent onset, or are difficult to control, or are progressively deteriorating is potentially linked to cortisol excess the aim of the study is to evaluate the prevalence of occult CS in metabolic syndrome patients.Method: In a cross-sectional study, 30 females with metabolic syndrome chosen from Endocrinology Clinic without any phenotypical features of...

A 83-year-old gentleman admitted with nausea and feeling generally unwell. Past medical history of hypertension, duodenal ulcer, previous gastric surgery, polymylagia rheumatica and type two diabetes mellitus. Chest XR showed right basal pneumonia which was treated with antibiotics. Patient admitted to significant weight loss therefore he had thoracic-abdominal CT scan performed which showed 4 cm by 4 cm solid cystic lesion in the left adrenal gland possibly malignant. Subsequ...

Hypercalcaemia is a common finding in numerous diseases processes but is non-specific to its cause. We report a case of a 55-year-old lady with known sarcoidosis who developed hypercalcaemia and elevated parathyroid hormone due to a parathyroid adenoma. Both these disease processes are independently associated with hypercalcamia, but it is unusual to have both in combination and difficult to establish which is the primary cause. In our case the diagnosis was complicated by a n...

A 76-year-old man with history of oesophageal carcinoma was successfully treated by surgery and radiotherapy 4 years previously. He presented with anorexia and 4 stones weight loss associated with abdominal discomfort. He was not on any medication. On examination blood pressure 100/60, no peripheral oedema, systemic examination otherwise was unremarkable. Soon after admission, he developed a generalised tonic clonic seizure requiring a Lorazepam and Phenytoin infusion to contr...

A 59-year-old Caucasian heterosexual man presented with malaise and dizziness. General examination revealed no peripheral oedema, no clubbing or lymphadenopathy and systemic examination was otherwise normal. His initial investigations showed hyponatremia with serum sodium 121 mmol/l, potassium 3.4 mmol/, serum osmolality 255 mOsml/kg, and urine osmolality 672 mOsml/kg. The rest of blood tests including; thyroid function, short Synacthen test, full blood count, liver functions,...

Introduction: We describe an 11-year-old boy (N) with Medium-Chain Acyl Dehydrogenase Deficiency (MCADD) diagnosed at one year of life and type 1 IDDM diagnosed at 10 years.History and discussion: N was diagnosed with MCADD when he was found hypoglycaemic. He was treated with the standard Emergency Regimen (a special feeding plan used if the child is unwell or not feeding well, wherein glucose polymer feeds are given frequently) and has had no further pr...