Endocrine Abstracts

Background: The penis has been compared to a barometer of endothelial health, being erectile dysfunction (ED) an early sign of endothelial dysfunction. The aim of the study was to investigate the association between ED and endothelial dysfunction in patients with HIV infection on ART.Methods: In this observational cross-sectional study we evaluated the prevalence and factors associated with ED in a cohort of 133 HIV-infected men. Evaluation tools include...

Introduction: Male hypogonadism is very frequent in men treated with highly active anti-retroviral therapy (HAART) for Human Immunodeficiency Virus-1 (HIV-1) infection, reaching a prevalence of about 20%. Literature data regarding the time course of serum total testosterone (T) levels in these patients are lacking.Aim of the study: To evaluate changes of T levels over time in HIV-positive men with an initial finding of low T (<300 ng/dl).<p class...

Background: The presence of the metabolic syndrome (MS) increases cardiovascular morbidity and mortality but few data is available on the outcome in subjects with the MS and subclinical atherosclerosis.Aim: We aimed to assess cardio- and cerebro-vascular events in subjects with MS and subclinical atherosclerosis.Methods: We followed-up for 5 years 339 subjects with asymptomatic carotid intima-media thickness >0.9 mm, of whom 13...

GH has well documented insulin antagonistic effects. By inference, GHD may be expected to result in increased insulin sensitivity. Young GHD children have a tendency to both fasting and readly provoked hypoglycaemia probably resulting from impaired hormonale counter-regolation. Increased insulin sensitivity could also contribute to their hypoglycaemia; however, this has not been directly demonstrated. Interestingly, susceptibility to hypoglycaemia in GHD children diminishes wi...

Introduction and objectives: Aim of this study is to evaluate the psycho-biological correlates of DM associated hypogonadism (DMAH).Methods: The Structured Interview SIEDY was employed along with several biochemical, psychological and instrumental investigations. We defined hypogonadal subjects (HY) those with a circulating total testosterone (T) below 10.4 nM.Results: We studied 1246 patients. More than 15% resulted affected by ty...

Introduction and objectives: Achieving and maintaining a penile erection are two essential components of the male sexual response. It has recently been suggested that distinct molecular mechanism could underlie the two disturbances. The aim of the present study is to verify possible clinical differences on pathogenetic factors underlying difficulties of achieving and maintaining an erection.Methods: We studied a consecutive series of 560 pa...

Introduction and objectives: Pathogenesis of delayed ejaculation (DE) is rather unknown, although the contribution of various psychological, marital, hormonal and neurological factors has been advocated.Methods: In this study we systematically investigated the relative relevance of the aforementioned factors in a large sample (1632) of men, seeking medical help for sexual dysfunction. Delayed ejaculation was defined according to Kaplan criteria. In parti...

Issues: No specific centre in asia for Osteoporosis patients treatment/rehabilitation. We used locally available Complementary Indian Medicines [CAM] for providing home based care in rural/tribal areas.Aims: To provide CAM to poor patients in collaboration with Traditional-faith-hearers. Evaluated cost-efficacy of CAM & response of pain of fractures to CAM alongside analgesics.Methods: from April 2014 to November 2018, 122 pati...

Issues: In developing nations diagnosis of diabetes brings mental-trauma/depression in family. Focused treatment for pediatric age-group is unavailable in developing-countries. 26% of diagnosed diabetics are children’s. Adequately trained physicians/Nurses in issues of pediatric-diabetes provide continuity of care, relief from depression and smooth transition from diagnosis to treatment. Qualitative collaborative relationship between these makes diabetics life bearable. O...

Introduction: Reduced health-related quality of life (HRQoL) is common in patients with chronic hypoparathyroidism treated conventionally with active vitamin D and calcium supplements.Aim: To determine the HRQoL of patients with hypoparathyroidism with disease persisting for more than 1 year.Methods: We identified 32 patients (women/men − 31/1, median (Me) age 48 years [38; 59.5]). The average duration of the disease was 4 ye...