Searchable abstracts of presentations at key conferences in endocrinology

ea0020oc3.1 | Reproduction/Stress/Endocrine Disruptors | ECE2009

Gapapentin for the treatment of hot flushes in women with natural or tamoxifen-induced menopause: a systematic review and a meta-analysis

Toulis Konstantinos , Tzellos Thrasivoulos , Kouvelas Dimitrios , Goulis Dimitrios , Tarlatzis Basil , Papadimas Ioannis

Context: Evidence suggests that gabapentin, a γ-aminobutyric acid analogue, is effective in the treatment of hot flushes in women with natural or tamoxifen-induced menopause.Objective and design: To investigate the efficacy and tolerability of gabapentin for the treatment of menopausal hot flushes, a systematic review of all pertinent trials and a meta-analysis of those that were randomized placebo-controlled (RCT) were performed.<p class="abste...

ea0041mte9 | (1) | ECE2016

Treatment of male hypogonadism

Goulis Dimitrios G

Traditionally, male hypogonadism is classified into hypogonadotrophic (the archetype being Kallmann syndrome) and hypergonadotrophic (the archetype being Klinefelter syndrome). Late-onset hypogonadism (LOH) constitutes a separate entity that can be defined as the state where men of advanced age demonstrate low serum testosterone (T) concentrations in combination with a spectrum of symptoms reminiscent of those of ‘classic’ male hypogonadism (e.g. reduced sexual funct...

ea0081ep1205 | Late Breaking | ECE2022

Psychological stress levels in men with infertility

Mintziori Gesthimani , Veneti Stavroula , Mousiolis Athanasios , Goulis Dimitrios

Aim: Infertility, defined as the non-achievement of pregnancy by a couple after 12 months of free sexual intercourse, affects 4 - 17% of couples worlwide. In 20% of cases, the cause is found exclusively or mainly in the man. The purpose of this study is to evaluate infertility as a risk factor for increased psychological stress.Material and Methods: A case – control study was conducted in which the levels of psychological stress of men with infertil...

ea0067gp35 | Poster Presentations | EYES2019

Energy deficiency, menstrual disorders and low bone mineral density in female athletes: a systematic review

Skarakis Nikitas S , Mastorakos George , Georgopoulos Neoklis , Goulis Dimitrios G

Background and aim: Low energy availability (LEA) may lead to menstrual disorders and low bone mineral density, predisposing to the female athlete triad (FAT) syndrome. The primary aim of this review was to systematically investigate the impact of sports on the energy status of professional female athletes compared to sedentary, recreationally active controls, with regard to their menstrual status and bone mineral density (BMD). A secondary aim was the estimation of the combin...

ea0049ep214 | Bone &amp; Osteoporosis | ECE2017

Efficacy and safety of bisphosphonate discontinuation in postmenopausal osteoporosis: a systematic review

Anagnostis Panagiotis , Paschou Stavroula , Mintziori Gesthimani , Lambrinoudaki Irene , Goulis Dimitrios

Introduction: The maximum period of bisphosphonate use has not been determined, as their long-term appliance has been associated with adverse effects, such as osteonecrosis of the jaw (ONJ) and atypical femoral fractures (AFF).The aim of this study was to systematically present existent data regarding the effect of bisphosphonate discontinuation on fracture risk and bone mineral density (BMD).Methods/design: MEDLINE, Scopus, EMBASE...

ea0041ep724 | Male Reproduction | ECE2016

Association of follicle stimulating hormone receptor single nucleotide polymorphisms with fertility in greek men

Tsitlakidis Damianos , Katopodi Theodora , Goulis Dimitrios , Papadimas Ioannis , Kritis Aristeidis

Background and Objective: Although several epidemiological studies have been conducted, the impact of Follicle Stimulating Hormone Receptor (FSHR) polymorphisms on male infertility remains unclear. The aim of this study was to investigate the prevalence of specific FSHR Single Nucleotide Polymorphisms (SNPs) in the Greek population and associate the latter with the clinical phenotype.Patients and Methods: We enrolled 96 subjects: men with idiopathic non-...

ea0056p196 | Bone ' Osteoporosis | ECE2018

Recurrent vertebral fracture after denosumab discontinuation in a male patient with severe osteoporosis

Anagnostis Panagiotis , Paschou Stavroula , Potoupnis Michael , Tsiridis Eleftherios , Goulis Dimitrios

Introduction: Discontinuation of denosumab may rarely lead to rebound fractures, although the evidence is low, since available data have derived from case reports and post-hoc analyses.Case presentation: A 45-year old Caucasian male was presented at the outpatient clinic in February 2016 for evaluation and management of severe osteoporosis, which had been complicated with multiple vertebral low energy fractures at the 10 th to 12th ...

ea0081p451 | Reproductive and Developmental Endocrinology | ECE2022

Association between basal androgen concentrations and number of follicles on the day of triggering final oocyte maturation in poor responders undergoing IVF - a prospective study

Bosdou Julia , Anagnostis Panagiotis , Savvaidou Despoina , Zepiridis Leonidas , Goulis Dimitrios , Grimbizis Grigorios , Kolibianakis Efstratios

Purpose: Androgens promote early follicular development and granulosa cell proliferation by augmenting follicle-stimulating hormone (FSH) receptor expression in granulosa cells. Several retrospective studies have evaluated the association between basal androgen concentrations and follicular development in women undergoing ovarian stimulation for in vitro fertilization (IVF) with conflicting results. The aim of this study was to investigate whether basal androgen concentrations...

ea0063p98 | Calcium and Bone 1 | ECE2019

The effect of vitamin D supplementation on sarcopenia indices: a systematic review and meta-analysis of randomized controlled trials

Gkekas Nifon K , Anagnostis Panagiotis , Siolos Pavlos , Kenanidis Eustathios , Potoupnis Michael , Tsiridis Eleftherios , Goulis Dimitrios G

Objective: To systematically review and meta-analyze the best available evidence regarding the effect of vitamin D supplementation, either as monotherapy or in combination with protein and exercise, on sarcopenia indices (muscle strength, muscle mass, muscle performance).Materials and methods: A comprehensive search was conducted in Medline, Cochrane Central, and Scopus databases, up to December 31st, 2018. Data were expressed as standardized ...

ea0063p522 | Calcium and Bone 2 | ECE2019

The effect of teriparatide on bone mineral density in a woman with severe lactation-related osteoporosis and multiple vertebral fractures

Anagnostis Panagiotis , Gkekas Nifon , Kenanidis Eustathios , Potoupnis Michael , Tsiridis Eleftherios , Goulis Dimitrios

Introduction: Lactation-related osteoporosis is a very rare entity, usually diagnosed with one or more fractures, during the early postpartum period. Due to the rarity of this condition, no consensus still exists with regard to thetype and optimal duration of treatment.Case presentation: A 39-year old Caucasian female was presented at the outpatient clinic in December 2016 for evaluation and management of severely low bone mineral density (BMD) and multi...