Endocrine Abstracts

Introduction: This study examined prevalence and risk factors of peri-odontitis in representative samples of Korean adults, with and without diabetes mellitus (DM). Additionally, we did subgroup analysis in diabetic patients with or without metabolic syndrome.Methods: This study analyzed data from the 2010 to 2015 the Korea National Health and Nutrition Examination Survey (KNHANES) in South Korea which include periodontitis and the parameter of metabolic...

Telmisartan, an angiotensin II type 1 receptor blocker (ARB), is widely prescribed for the treatment of hypertensive patients with simultaneous diabetes mellitus (DM). Unlike other ARBs, telmisartan is reported to have various ancillary effects as well as common blood pressure-lowering effect. In this regard, telmisartan improves endothelial dysfunction and cardiovascular complications in DM patients and is recently reported to reduce new-onset DM incidence. However, effects a...

Introduction: Previously we investigated the relationship between obesity and depression in Korean adults using data from a population-based sample from the 2014 Korea National Health and Nutritional Examination Survey (KNHANES) by cross-sectional study. We further investigated about relationship between body image perception, diet trial and depression in -depth study.Methods: In total, 4,026 subjects (1,692 men, 2,334 women) aged 19–69 years partic...

Background: The risk of thyroid cancer in large thyroid nodules greater than 4 cm has been reported to be increased. Some authors insist that diagnostic lobectomy should be performed in patients with large thyroid nodules, irrespective of fine needle aspiration cytology (FNA) results. However, consensus on that matter has not been met. We wanted to investigate the risk of thyroid malignancy according to the size of the thyroid nodules, based on FNA results.<p class="abstex...

Background: In the UK, recombinant human growth hormone(rhGH) is approved for children with growth failure associated with six different conditions. According to NICE guidelines, clinicians should have a comprehensive discussion with patients and/or caregivers about treatment options. Research shows that patients retain only about 20% of the information provided during a consultation. This can be improved to around 50% when written information is also provided...

SYNGR3 is involved in the re-uptake of dopamine (DA) into striatal pre-synaptic terminals. Here we elucidate the genetic control of human SYNGR3 gene (SYNGR3).Methods and Intermediate Results: Step 1 Potential cis-acting in 2kb upstream of the transcription initiation site (TIS) of SYNGR3 were investigated using the MatInspector algorithm. Three potential Nurr1 binding sites were identified. Step 2 PCR amplification (human DNA as templa...

Background: Gas-forming pyogenic liver abscess is an uncommon, life-threatening infection that is usually found in poorly-controlled diabetic patients. Here, we experienced a case of gas-forming pyogenic liver abscess in diabetes caused by Klebsiella pneumoniae.Clinical case: A 77-year-old man with 25-year history of diabetes was admitted due to fever for 2 days. On the physical examination, right upper quadrant tenderness of the abdomen was present. Ini...

The usual management at our centre for patients awaiting phaeochromocytoma surgery involves pre-operative titration of alpha blockade with frequent clinic visits for blood pressure (BP) and heart rate (HR) monitoring. The COVID-19 pandemic restricted our ability to consult with patients frequently. To reduce infection risk, we incorporated virtual BP monitoring using a Microsoft Excel template coupled with regular remote consultations. We present a clinical case highlighting o...

We present the case history of a 62 year old male, who was recently diagnosed with sarcoidosis which was confirmed on biopsy of a calf nodule. CT scan revealed pulmonary involvement. Our patient had low vitamin D 12 nmol/l (nr 50–100) and initial adjusted calcium was 2.48 mmol/l (2.13–2.63). DEXA bone density scan revealed osteopenia. He was commenced on loading dose of colecalciferol 40,000 units weekly and received 3 doses. He presented 1 month later with polydipsi...

Introduction: Hypercalcemia is mostly caused by primary hyperparathyroidism and malignancy. Parathyromatosis is a rare condition characterized by multiple nodules of hyperfunctioning parathyroid tissue scattered throughout the neck and superior mediastinum, which can present a diagnostic and therapeutic challenge.Case report: A 56-year-old woman visited the ER due to chest pain, left-sided neck edema, and hematoma. The day before, she experienced left-si...