Endocrine Abstracts

BackgroundThe current COVID-19 pandemic is the worst from world infection outbreaks have occurred frequently in the last two decades, and it has led to significant mortality. Although the respiratory system is the most prominent target of SARS-CoV-2, extrapulmonary involvement are important contributors of its morbidity and mortality. A number of symptoms occur in these patients due to the involvement of various endocrine glands. The nervous, endocrine, ...

BackgroundThe prevention of complications and improvement of metabolic control and state of health in diabetes cannot be effective only with medications. And now we need to develop different approaches – not only up to date pharmacological treatment of diabetes, but change the Self-Management Behavior among patients with Type 2 Diabetes.AimsTo assess the current status of diabetic self-management behavio...

BackgroundIt has often been argued that important psychosocial factors such as depression, anxiety and emotional stress can influence self-help behavior and therefore negatively affect glycemic control. In turn, the reduced quality of life due to chronic illness is a mediated cause of poor glycemic control. Also, attention is drawn to the prevalence of cognitive impairments and dementia.Aims1) to assess the p...

Introduction: Recent data indicate that women affected by the polycystic ovary syndrome (PCOS) are at a greater risk for cardiovascular disease (CVD). The objective of this study was to evaluate the effect of the association ethinylestradiol 30 μg–drospirenone 3 mg (DRP/EE30 μg) plus metformin and weight loss on surrogate markers of CVD in PCOS.Methods: Twenty-five young women with PCOS (mean age 22.76±0.83 years, body mass index (BMI...

Aim: The aim of our study was to assess the presence of endothelial dysfunction and of increased carotid intimae-media thickness (IMT), two precocious markers of atherosclerosis in PCOS subjects. Simultaneously, their relationship with some metabolic, hormonal and anthropometric parameters was analyzed.Methods: The study group consisted of 45 women with PCOS (age=23.1±4.1 years, body mass index (BMI) =28.4±5.9 kg/m2). Thirty-two heal...

Background: Calcitonin (CT) is a specific marker of Medullary Thyroid Carcinoma (MTC). However, its routine measurement in the assessment of nodular thyroid disease (NTD) remains controversial because MTC is rare and CT may have false positive results.Objective: To evaluate the frequency of hypercalcitoninemia (hyperCT) among patients with benign NTD and to disclose possible underlying factors.Methods: Retrospective study including...

Background: Primary thyroid angiosarcoma (PTA), previously considered a vascular type of anaplastic thyroid carcinoma (ATC), is a rare, aggressive malignant mesenchymal tumor, with a peak incidence in the seventh decade of life. PTA can present as an ATC, a more frequent type of thyroid malignancy. Differential diagnosis is of major importance, as the management and prognosis differ significantly.Case report: A 72-year-old woman presented for a 2 month h...

Background: Bilateral neck exploration (BNE) as a routine surgery for PHPT is favored by many experts in endocrine surgery as it may provide the identification of preoperatively undetected multiglandular disease. But for a large cohort of patients BNE remains unnecessary and its possible higher rate of surgical complications is being widely discussed.Objectives: The aim of the study was to evaluate the complication rates of bilateral neck exploration in ...

Introduction: Cushing disease (CD) is the leading cause of endogenous hypercortisolism, caused by a pituitary tumor that produces ACTH. Treatment modalities include transsphenoidal selective adenomectomy (TSA), pharmacological therapy, radiotherapy (RT), and bilateral adrenalectomy (BA). The goal of our study was to analyze the outcomes of Cushing disease treatment in UHC Zagreb.Method: This retrospective study comprised 64 patients with CD (51 (80% wome...

Background: Medullary thyroid cancer is a rare neuroendocrine neoplasm that can secrete variety of hormones, including ACTH. Cushing syndrome due to ectopic ACTH secretion is a rare complication of medullary thyroid cancer, usually accociated with metastatic disease. Around 50 percent of patients with medullary thyroid carcinoma and ectopic Cushing syndrome die due to complications of hypercortisolism. Based on the aforementioned, efficient management of hypercortisolism is cr...