Endocrine Abstracts

Vitamin D deficiency has been observed in diabetes mellitus type 2 patients. It has been found to be related to poor glycemic control in diabetes mellitus type 2 patients as well as in patients with gestational diabetes. The administration of vitamin D in diabetes mellitus type 2 patients with vitamin D deficiency has been found to have conflicting results on blood glucose control. The aim was to assess the effect of vitamin D administration in diabetes mellitus type 2 patient...

Polymyalgia rheumatica is a chronic autoimmune inflammatory rheumatic disorder of unknown aetiology. Hashimoto thyroiditis is an autoimmune thyroid disorder characterised by the presence of antithyroid antibodies. Hashimoto thyroiditis has been described in patients with systemic autoimmune disorders such as systemic lupus erythematosus. The aim of the study was to describe the case of a patient who had polymyalgia rheumatica and developed Hashimoto thyroiditis.<p class="a...

The adrenolytic agent mitotane [o,p’-DDD or 1,1-(o,p’-dichlorodiphenyl)-2,2-dichloroethane] is a derivative of the insecticide DDT and is used for the treatment of adrenal carcinoma. It induces necrosis and atrophy of the adrenal cortex. Estrogenic action after single exposure but intense antiestrogenic action after repeated exposure of porcine ovarian follicles has been observed in vitro (Wojtowicz et al. 2004).The aim of the stu...

Introduction: Systemic lupus erythematosus is a systemic autoimmune disease, which often necessitates the administration of corticosteroids for its treatment. Cushing’s syndrome is a disorder characterized by the endogenous hypersecretion of cortisol.Aim: The aim was to describe the case of a patient who had systemic lupus erythematosus, was on therapy with corticosteroids and developed Cushing’s syndrome.Case description...

Introduction Severe infection from the SARS-CoV-2 virus is associated with various manifestations, including hematological manifestations. Thrombotic events or a tendency to develop thrombotic events also characterize severe COVID-19 disease and may be related to fatalities. Vitamin D is known to have immunomodulating properties and to enhance the body defense system against invading pathogens and to have immunostimulatory properties as far as the innate immune response is con...

Rheumatoid arthritis is a systemic autoimmune inflammatory disease characterized by severe pain, if left untreated. Primary hyperparathyroidism is a systemic disorder characterized by disordered calcium metabolism leading to increased serum calcium and PTH levels. Primary hyperparathyroidism may be due to the presence of a parathyroid adenoma or parathyroid hyperplasia. The aim was to present a cohort of patients with rheumatoid arthritis who presented with primary hyperparath...

Introduction: Pregnancy is characterized by increased secretion of estrogens and cortisol. Estrogen is used to prepare the maternal environment for the fetus. Cortisol induces a state of immunosuppression to avoid loss of the fetus, which, by definition, is at least partly a foreign organism. Parturition is characterized by estrogen and cortisol withdrawal. It leads to a rebound in immunity and may be accompanied by the development of autoimmune disease. Autoimmune thyroid dis...

Introduction: The SARS-CoV-2 virus has caused the recent pandemic. Most affected patients have gone through a rather mild disease. However, some of the patients have gone through a severe illness requiring admission to an acute care unit. Some survived while others succumbed to the disease. In some patients the SARS-CoV-2 infection was characterized by neurological manifestations. One of these is transverse myelitis thought to be caused either by the virus itself as the SARS-C...

Introduction: Ankylosing spondylitis (AS) is a chronic systemic inflammatory disorder which affects the sacroiliac joints, the axial skeleton, peripheral joints as well as other organs. It develops in young adults causing significant mobility and functional disorders, with associated severe dysfunction or disability. Ankylosing spondylitis has serious adverse effects on the ability to work and quality of life. Biologic agents are used for the treatment of AS, this effect havin...

Introduction: Stress is a known risk factor for the development of Graves’ disease. We have previously described the role of bereavement as an inducing factor for Graves’ disease. Bereavement as an inducing factor for Graves’ disease was shown to affect primarily female patients after the loss of a loved one. However, it appears that other stressful life events may also cause Graves’ disease.Aim: The aim of the study was to describe t...