Endocrine Abstracts

Introduction: Subclinical hypothyroidism (SCHT) in pregnancy has been associated with adverse obstetric and perinatal outcomes. However, few studies have investigated the evolution of postpartum thyroid function in women first diagnosed with SCHT in pregnancy (gestational SCHT).Objective: To determine the evolution of thyroid function (TF) and the clinical and biochemical factors related to the long-term persistence of hypothyroidism (HT) in women with g...

Introduction: Recurrences of differenciated thyroid carcinoma are occasionally hard to locate; rhTSH-stimulated FDG PET-CT may offer a higher sensitivity, particularly when thyroglobulin in high, but its utility has not been clearly established. Methods: Review of the patient’s clinical record Results: A 61 years old woman noticed a right anterior neck lump when she was 47; FNAC was suggestive of a solid papillary thyroid carc...

Introduction: Hormone-producing pituitary cell lineages derive from SOX2+ embryonic precursors. These cells maintain multipotency into early postnatal life, acting as the resident population of pituitary stem cells (PSCs) and contributing extensively to all the endocrine cell lineages. Additionally, paracrine signalling from PSCs is important for cell proliferation of neighbouring progenitors (PMC7803373). It is not known if SOX2+ PSCs are involved in the regulation of additio...

Objective: The carbohydrate metabolism dysfunctions are common in critical ill patients with diabetes or stress hyperglycaemia and the correct management of them has an important prognostic value. Despite its limitations, capillary glucose (CG) was collected more than arterial glucose (gold standard) because of its good correlation. However, the usefulness of intermittent intersticial glucose monitoring (IGM) in keeping blood glucose within target range in critical ill patient...

Introduction and Objectives: Pheochromocytomas and paragangliomas are rare neuroendocrine tumors derived from enterochromaffin tissue, mostly catecholamine-producing, adrenal gland (PCC) or extra-adrenal paraganglia (PGL). We were struck by the high incidence of these in our health care area, so we decided to study them. The aim of this work is to evaluate the clinical characteristics and epidemiological factors of patients diagnosed with PCC or PGL.Mate...

Objective: Evaluate the utility of analytical determination of parathyroid hormone assay in fine-needle aspirate as a diagnostic test for parathyroid adenoma in patients with primary hyperparathyroidism.Material and Methods: retrospective observational study of 58 patients diagnosed with primary hyperparathyroidism in our hospital who underwent ultrasound-guided FNA of lesions compatible with parathyroid adenoma with determination of PTH in fine-needle a...

Introduction: In Spain, the specialist in endocrinology and nutrition is the reference in the care of patients with diabetes mellitus. In the year 2022, access to these specialists has been facilitated in the south of Gran Canaria. The aim of the study is to determine how this has influenced the management of type 2 diabetes (T2D).Methods: We included those patients with T2D assessed by the Endocrinology service in 2022 in which two analyses were perform...

Objective: To evaluate the nutritional status in patients with type 1 diabetes mellitus (DM1) or latent autoimmune diabetes in adults (LADA).Methods: Observational transversal clinical study in patients with DM1/LADA. Nutritional assessment was performed using bioelectrical impedance analysis (BIA), dynamometry, ultrasound of rectus femoris muscle and subcutaneous fat tissue, functional tests and laboratory parameters. Statistical analysis was performed ...

Although we know the gene alterations associated with KAL 2, at present we still do not know certain mutations of the fibroblast factor receptor 1 gene (FGFR gene) that even show complete penetrance of the syndrome. Kallman syndrome is a genetic disease of embryonic development characterized by the association of hypogonadotropic hypogonadism due to GnRH hormone deficiency because of agenesis or hypoplasia of the olfactory sulci. Three subtypes have been described; the classic...

Background: Thionamides are a class of drugs used to control thyrotoxicosis. A wide range of systemic adverse effects have been described, including agranulocytosis, rash, fever, arthralgia, hepatitis and even drug-induced lupus. Besides, there are some uncommon events related to their use, such as pleural effusion (only eight cases have been previously reported). We report a case of methimazole-induced eosinophilic pleural effusion.Case: Our patient is ...