Searchable abstracts of presentations at key conferences in endocrinology

ea0090p772 | Thyroid | ECE2023

Predictive factors for sufficient cytological result after first nondiagnostic thyroid fine-needle aspiration biopsy result

Dilek Dellal Kahramanca Fatma , Bestepe Nagihan , Meryem Kiran Merve , başer husniye , Ozdemir Didem , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

Aim: To determine whether there is any factor that can predict sufficient results in second thyroid fine-needle aspiration biopsy (FNAB) after first nondiagnostic cytological result.Materials and method: Nodules with non-diagnostic result after first FNAB were included and separated into two groups as sufficient (Group-1) and insufficient (Group-2) second FNAB. Results: Second FNAB was performed on 643 nodules of 443 patients with ...

ea0090p777 | Thyroid | ECE2023

Rapidly-Growing Thyroid Mass: is the Diagnosis Always Anaplastic Cancer?

Yiğit Koroğlu Ekin , Turan Kubra , Pınar Altay Feride , Karadayı Bilgehan , Kılıcarslan Aydan , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

A 87 year old woman admitted with complaints of hoarseness and a palpable mass which she noticed 1 week ago. She had hypothyroidism for 25 years. On examination, there was a hard and fixed palpable 4x4 cm mass on the right side of the neck. In laboratory evaluation, thyroid function tests were normal, thyroid auto-antibodies were positive, calcitonin was normal, C-reactive protein was 224 mg/l and liver and kidney function tests were normal. Thyroid ultrasonography revealed a ...

ea0090ep270 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Ultrasonographic features of thyroid nodules and thyroid gland in obese patients

Cuhacı Seyrek Neslihan , Ince Nurcan , Faki Sevgul , Baser Husniye , Tam Abbas Ali , Polat Şefika Burcak , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

Objective: Thyroid nodules are one of the most common thyroid diseases. Ultrasonography is an reliable and the most commonly used imaging method in the evaluation of thyroid nodules with a high sensitivity (Sn) and specificity (Sp). The prevelance of obesity, especially severe obesity, is increasing at an alarming rate in the worldwide. Although obesity and thyroid disorders are related to each other, the pathological relationship between those is not clear. Several studies ha...

ea0090ep341 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Metformin-Associated Lactic Acidosis: A Case Report

Baykal Gokhan , Houssein Mehdi , Onal İrem , Şahiner Enes Seyda , Bicer Cemile , Imga Narin Nasiroglu , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

Introduction: Metformin is widely used as the first-line therapy for patients with type 2 diabetes, and its most common adverse effects are gastrointestinal. Metformin-associated lactic acidosis (MALA) is a rare but serious adverse effect in patients with type 2 diabetes or patients who attempt suicide with metformin overdose. Here, we report the case of a 22-year-old woman who developed severe lactic acidosis after high-dose metformin was taken for a suicide attempt.<p cl...

ea0090ep816 | Pituitary and Neuroendocrinology | ECE2023

A Rare Pituitary Pathology: Patient With Crooke Cell Corticotroph Adenoma

Yiğit Koroğlu Ekin , Aydin Cevdet , Keskin Caglar , Faruk Turkoğlu Omer , Gureşci Servet , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

However ACTH secreting adenomas are one of the most common functional pituitary tumors, subtypes such as Crooke cell corticotroph adenoma(CCCA) are relatively rare. We present here a patient with CCCA who had severe hypercortisolism mimicking ectopic ACTH syndrome. A 69 years old female patient admitted to emergency department after a fall. On cranial MRI,’a 3.5x2.5x3cm mass appearance with a sellar-suprasellar location, which is compressing the optic chiasm, expanding th...

ea0090ep818 | Pituitary and Neuroendocrinology | ECE2023

A Pituitary Neoplasm with an Aggressive Course: Silent Corticotroph Adenoma

Yiğit Koroğlu Ekin , Houssein Mehdi , Tural Balsak Belma , Bahadır Burak , Gureşci Servet , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

Patient is a 43 years old female without any known additional disease. A pituitary mass was seen in the cranial MRI taken due to the complaint of forgetfulness. Pituitary MRI of the patient revealed a ’large intrasellar mass of 3.2x3x2.3 cm, which expanded the sella and pressed the optic chiasm’. The patient didn’t describe any symptoms other than forgetfulness. She didn’t have galactorrhea, cushingoid or acromegaloid appearance. Patients laboratuary evalua...

ea0037ep908 | Thyroid cancer | ECE2015

Ratio of lymph node aspiration washout thyroglobulin levels to whole blood and serum washout thyroglobulin levels in patients with differentiated thyroid carcinoma: a new approach for standardisation of measurements and increased accuracy

Aydin Cevdet , Ozdemir Didem , Sacikara Muhammed , Polat Sefika Burcak , Yazgan Aylin Kilic , Turkolmez Seyda , Onal Eda Demir , Ersoy Reyhan , Cakir Bekir

Introduction: High values of fine needle aspiration washout thyroglobulin (FNA-Tg) are diagnostic for metastatic lesions of thyroid cancer. However, there is not a consensus on cut-off for high Tg level. The most important confounding factor for FNA-Tg is inability to calculate Tg per unit volume because residual aspiration material in the needle cannot be known exactly. Another problem is possible contamination of whole blood during lymph node aspiration. In this study, we ai...

ea0035p61 | Adrenal Medulla | ECE2014

A difficult case of ectopic Cushing's syndrome due to ACTH-producing pheochromocytoma presented with normal fractionated urinary catecholamines and metanephrines

Topaloglu Oya , Polat Sefika Burcak , Ogmen Berna Evranos , Baser Husniye , Dirikoc Merve , Tokac Mehmet , Sak Serpil Dizbay , Ersoy Reyhan , Cakir Bekir

Introduction: Ectopic ACTH secretion by pheochromocytoma causing Cushing’s syndrome has been reported rarely. Here, we present a patient with ectopic ACTH-dependent Cushing’s syndrome, caused by a pheochromocytoma with normal fractionated 24 h urinary catecholamines and metanephrines.Case report: A 48-year old female patient admitted to our clinics with the complaints of severe hypertension despite receiving anti hypertensive therapy. Severe he...

ea0032p1102 | Thyroid cancer | ECE2013

The diagnostic accuracy of ultrasound-guided fine needle aspiration biopsy (FNAB) in thyroid nodules 3 cm and above in size and sonographic feature differences between malignant and benign nodules

Ucler Rifki , Usluogullari Celil Alper , Ali Tam Abbas , Ozdemir Didem , Yalcin Samet , Kiyak Gulten , Ersoy Pamir Eren , Guler Gulnur , Ersoy Reyhan , Cakir Bekir

Introduction: Nodule diameter was considered to be related with thyroid cancer. Whether under ultrasound (US) guidance or not, FNAB has some limitations particularly in big nodules. In this study, we aimed to evaluate diagnostic value of US-FNAB in nodules bigger than 3 cm or more. We also compared ultrasonographical features of benign and malignant nodules.Material and methods: Data of 267 patients operated for nodulary goiter were screened retrospectiv...

ea0032p1116 | Thyroid cancer | ECE2013

Treatment, follow up and prognostic factors of papillary microcarcinoma

Usluogullari Alper Celil , Onal Eda Demir , Ozdemir Elif , Ucler Rifki , Kiyak Gulten , Ersoy Pamir Eren , Yalcin Samet , Guler Gulten , Ersoy Reyhan , Cakir Bekir

Introduction: The incidence rate of papillary thyroid microcarsinoma (PTMC) has almost doubled during the recent years but treatment and follow up is still a matter of debate. In this study we aimed to analyze clinical and histopathological risk factors at the time of diagnosis and to observe their implications for treatment, follow up and prognosis.Patients and methods: Two hundred forty-eight PTMC patients were included in this study. The age, sex, the...