Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

Published by BioScientifica

Page 13 of about 185 results

ea0073aep62 | Adrenal and Cardiovascular Endocrinology | ECE2021

Patients with congenital adrenal hyperplasia show an adverse cardiovascular risk profile compared to patients with autoimmune adrenalitis

Hannes Beiglböck , Magdalena Bögl , Fellinger Paul , Metz Matthaeus , Vila Greisa , Luger Anton , Trattnig Siegfried , Kautzky-Willer Alexandra , Krssak Martin , Krebs Michael , Peter Wolf

BackgroundDespite adequate hormone replacement therapy, evidence suggests an increased mortality in patients suffering from primary adrenal insufficiency, mainly because of cardiovascular diseases. Congenital adrenal hyperplasia (CAH) and autoimmune adrenalitis (AI) are two entities with a different pathophysiological background and might therefore show divergent cardiovascular risk profiles.Methods9 patients...
0 shares

ea0073aep445 | General Endocrinology | ECE2021

Vitamin D deficiency in young adults and the question of the need for early replacement for the primary prevention of osteoporosis

Tatjana Bačun , Ivan Lekić , Jelena Šarić , Barbara Bačun , Željko Debeljak , Dunja Degmečić , Vatroslav Šerić

IntroductionLow concentrations of vitamin D are associated with decreased calcium absorption, negative calcium balance, and compensatory growth of parathyroid hormone, resulting in excessive bone resorption. The first step in preventing osteoporosis is to ensure a proper diet, especially calcium and vitamin D intake.Aim of the studyThe aim of this study was to determine the concentration of 25-hydroxyvitamin ...
0 shares

ea0081p710 | Reproductive and Developmental Endocrinology | ECE2022

Age- and body mass index-adjusted association between insulin sensitivity and risk factors for cardiovascular disease in polycystic ovary syndrome

Kałużna Małgorzata , Krauze Tomasz , Kompf Pola , Ziemnicka Katarzyna , Andrzej Wykretowicz , Ruchala Marek , Guzik Przemyslaw

Introduction: Impaired insulin sensitivity accompanies polycystic ovary syndrome (PCOS). Women with PCOS are usually at risk of premature cardiovascular disease, which increases with age and body weight. We studied the link between insulin sensitivity measured by the Matsuda Insulin Sensitivity Index (MISI) adjusted to body mass index (BMI) and age in otherwise healthy PCOS women.Methods: 250 adult women with PCOS of reproductive age (18-43 years old) un...
0 shares

ea0049ep1074 | Pituitary - Clinical | ECE2017

Body composition and bone mineral density in male patients with isolated hypogonadotropic hypogonadism

Kałużna Małgorzata , Człapka-Matyasik Magdalena , Przeorska Dorota , Ziemnicka Katarzyna , Ruchała Marek

Isolated hypogonadotropic hypogonadism (IHH) is known to decrease bone mineral density due to lack of pubertal surge of gonadotropins and deficiency of sex steroid hormone. Gonadal steroid hormones imbalance affects body composition. Nineteen Caucasian men, 22–48 year old (mean±S.D. 33±7.65) diagnosed with IHH (8 normosmic, 11 anosmic or hyposmic) were enrolled into the study. 14 patients were on hormone replacement therapy (HRT), 5 patients were ...
0 shares

ea0029oc7.6 | Adrenal Clinical | ICEECE2012

Progressively increased patterns of subclinical cortisol hypersecretion in adrenal incidentalomas differently predict major metabolic and cardiovascular outcomes: a large cross-sectional study

Di Dalmazi G. , Vicennati V. , Rinaldi E. , Morselli-Labate A. , Giampalma E. , Mosconi C. , Pagotto U. , Pasquali R.

Background: Subclinical Cushing’s syndrome (SCS) is defined as alterations in hypothalamic–pituitary–adrenal axis without classic signs or symptoms of glucocorticoid excess. It is still controversial whether SCS leads to metabolic and cardiovascular diseases, and if the degree of subclinical hypercortisolism may predict these clinical outcomes.Aim: To evaluate the prevalence of hypertension, type-2 diabetes (T2D), coronary heart disease (C...
0 shares

ea0029p17 | Adrenal cortex | ICEECE2012

Prolonged zona glomerulosa insufficiency causing hyperkalemia in primary aldosteronism following adrenalectomy

Fischer E. , Pallauf A. , Degenhart C. , Beuschlein F. , Bidlingmaier M. , Linsenmaier U. , Mussack T. , Ladurner R. , Hallfeldt K. , Reincke M.

Context: Unilateral adrenalectomy is the therapy of first choice in aldosterone producing adenoma (APA). Improvement of blood pressure (BP) and hypokalemia is achieved in the majority of patients. Because of hypoaldosteronism, hyperkalemia can develop in the postoperative course. Our aim was to analyze the frequency of hyperkalemia, to determine the cause of hypoaldosteronism and to assess the influence of preoperative mineralocorticoid antagonist (MRA) therapy at our center.<...
0 shares

ea0029p212 | Calcium &amp; Vitamin D metabolism | ICEECE2012

Cinacalcet treatment in MEN1-associated hyperparathyroidism: a clinical trial

Filopanti M. , Verga U. , Ermetici F. , Eller-Vainicher C. , Corbetta S. , Luca P. , Beck-Peccoz P. , Spada A.

Introduction: In type 1 multiple endocrine neoplasia (MEN1), primary hyperparathyroidism (PHPT) is a challenging problem due to the high post-surgery recurrence rate. Cinacalcet is a calcimimetic agent which showed to be effective in patients in whom surgery is contraindicated or refused. In this study we assessed the efficacy and the safeness of cinacalcet in MEN1 patients, in comparison with patients with sporadic PHPT (sPHPT). Moreover, the influence of Arg990Gly CASR polym...
0 shares

ea0029p216 | Calcium &amp; Vitamin D metabolism | ICEECE2012

Serum cystatin C is a reliable predictor of renal function and cardiometabolic risk in primary hyperparathyroidism

Ermetici F. , Filopanti M. , Verga U. , Passeri E. , Zelaschi R. , Raggi M. , Beck-Peccoz P. , Spada A. , Corbetta S.

Primary hyperparathyroidism (PHPT) negatively affects renal function. It is known that chronic kidney disease is a predictor of cardiometabolic diseases. Cystatin C (cystC), an alternative measure of renal function, has been associated with adverse cardiovascular events and cardiometabolic risk factors. This study was aimed to evaluate serum cystC, its relationships with PTH and cardiometabolic risk in patients with PHPT.The following parameters were mea...
0 shares

ea0029p220 | Calcium &amp; Vitamin D metabolism | ICEECE2012

Cardiac structure and functions in patients with asymptomatic primary hyperparathyroidism

Yilmaz B Aktas , Akyel A. , Kan E. , Ercin U. , Tavil Y. , Bilgihan A. , Cakir N. , Arslan M. , Toruner F Balos

Introduction: Primary hyperparathyroidism is associated with cardiovascular disease. In addition, data about cardiovascular abnormalities in patients with asymptomatic primary hyperparathyroidsm (APHPT) is’nt clear. In this study, we aimed to examine the cardiac structure–functions and hs-CRP levels in patients with APHPT.Materials and method: Thirty-one patients with APHPT and 32 sex- and age-matched control cases with similar cardiac risk fac...
0 shares

ea0029p302 | Cardiovascular Endocrinology and Lipid Metabolism | ICEECE2012

Recombinant erythropoietin treatment enhances mitochondrial function in human skeletal muscle

Plenge U. , Guadeloupe-Grau A. , Andersen P. , Carsten L. , Dela F. , Pott F. , Jorn H. , Belhage B. , Boushel R.

Erythropoietin (Epo) treatment has been shown to induce mitochondrial biogenesis in cardiac muscle along with enhanced mitochondrial capacity in mice. We hypothesized that recombinant human Epo (rhEpo) treatment enhances skeletal muscle mitochondrial oxidative phosphorylation (OXPHOS) capacity in humans. In six healthy volunteers rhEpo was administered by s.c. injection over eight weeks with oral iron (100 mg) supplementation taken daily. Mitochondrial OXPHOS was quantified by...
0 shares

Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 | Privacy policy | Cookie settings

BiosciAbstracts

Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Find out more