Searchable abstracts of presentations at key conferences in endocrinology

ea0007p277 | Clinical case reports | BES2004

A diagnostic pitfall: concomitant occurrence of macroprolactinaemia and a non-secreting pituitary adenoma

Krishnan U , Qureshi M , Burrows J , Labib M , Fiad T

We present the case of a 49 year old man who initially presented to his GP with complaints of tiredness, weight gain and tingling in his right hand. GP requested thyroid hormone measurements which showed FT4 level of 3.4 picomoles per litre and TSH 10.89 milli international units per litre. The inappropriately low TSH level raised the possibility of central hypothyroidism and triggered further investigations which revealed a low level for GH, LH, FSH, testosterone and cortisol...

ea0007p304 | Clinical practice | BES2004

An audit to evaluate the second radioiodine challenge scan in patients with thyroid cancer

Batra R , Perros P , Fenwick J , Mallick U

The Northern Cancer Network Guidelines produced in 1999 for the management of differentiated thyroid cancer (DTC) state that patients should undergo two challenge scans after total thyroidectomy and radioiodine ablation; 6 months and 18 months after ablation. Due to the significant morbidity associated with thyroid hormone withdrawal in preparation for challenge scans, the need for the second scan has been questioned in the presence of a negative first scan and undetectable se...

ea0005p24 | Clinical Case Reports | BES2003

Vanishing bone: Stabilisation of Gorham-Stout disease during antiresorptive therapy

Hammer F , Wesselmann U , Tunkel J , Arlt W , Allolio B

Gorham-Stout disease is a rare, potentially life threatening skeletal disorder of unknown aetiology. It is characterized by local proliferation of abnormal vessels associated with profound osteolysis. Optimum treatment remains to be established. Herein we report the case of a 45-year-old woman who presented with left-sided thoracic pain, which had gradually increased over the last nine months. Physical examination revealed a primary lymphoedema of the left arm, which had devel...

ea0005p27 | Clinical Case Reports | BES2003

Delayed carbimazole induced agranulocytosis precipitating thyroid crisis

Srinivas U , Stanaway S , Worth R , Ewins D

Agranulocytosis is a well recognised but rare side effect of carbimazole therapy which usually occurs within the first 3 months of treatment .We report the case of a 55 year old woman with Graves disease, who developed delayed carbimazole induced agranulocytosis, precipitating a thyroid crisis.Our patient presented with clinical and biochemical evidence of hyperthyroidism in 1998. She was treated with carbimazole and thyroxine in a standard block and replace regimen, this was ...

ea0073ep77 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Does COVID cause diabetes?

I Malik , A Rafi , M Sheehy , U Healy , S Hoashi

Little is known on the impact of acute COVID-19 infection on causation of diabetes. We report on a 36 years old man from Nigeria who presented with diabetic ketoacidosis (DKA) with typical osmotic symptoms of polyuria and polydipsia, fatigue and weight loss over 2 weeks. He tested positive for SARS-COV2 by PCR. The initial laboratory results: Random glucose 30.6 mmol/l, capillary blood ketones 7.4 mmol/l, pH 7.22, bicarbonate 7.5 mmol/l. Despite insulinopaenic state, at presen...

ea0073aep408 | General Endocrinology | ECE2021

A new cause of endogenous hyperinsulinism?

Caballero Manuel J , José Ignacio Fernández Peña , Eyvee Arturo Cuellar Lloclla

We present the case of a patient who started having repeated episodes of symptomatic hypoglycemia at the age of 50.Medical historyFather had type 2 diabetes. Former smoker, moderate alcohol consumption. Chronic otitis media with cholesteatoma, surgically removed. Congenital cataract operated at the age of 3.Clinical courseAt around the age of 50, the patient started having sporadic epis...

ea0073aep494 | Pituitary and Neuroendocrinology | ECE2021

Cabergoline treatment for non functioning pituitary macroadenomas

Pappa Dimitra , Thoda Pinelopi , Anastasia – Konstantina Sakali , Barmpa Eleftheria , Georgiou Eleni , Gountios Ioannis , Alexandra Bargiota

IntroductionCabergoline seems to be a promising and effective medical treatment for the more agressive Non Functioning Pituitary Adenomas (NFPAs) by reducing or keeping tumor’s size stable long-term. Here we present the experience of our centerMethodsWe studied 7 patients with NFPAs attending our clinic the last 10 years (median period 42 months, range 12 to 114 months), in whom cabergoline was started d...

ea0073aep379 | Endocrine-Related Cancer | ECE2021

Ectopic cushing’s syndrome due to an acinic type parotid carcinoma

Zerva Dimitra , Pappa Dimitra , Mparmpa Eleftheria , Anastasia –Κonstantina Sakali , Thoda Pinelopi , Georgiou Eleni , Gountios Ioannis , Alexandra Bargiota

IntroductionEctopic Cushing’s syndrome(ECS) is responsible for 15–20% of all cases of ACTH dependent Cushing’s syndrome. We present here a very rare case of ECS due to an acinic parotid carcinoma (ACC).PresentationA 44 year old woman with a medical history of metastatic ACC parotid carcinoma and type 1 diabetes mellitus (T1DM), referred to our department, due to cushingoid features, progressive...

ea0081ep618 | Endocrine-Related Cancer | ECE2022

Pro-inflammatory biomarkers in Papillary thyroid cancer

Bangaraiahgari Ramesh , Panchangam RAmakanth Bhargav , Bangaraiahgari Rajesh , U Udaya Kumar , Mayilvaganan Sabaretnam

Introduction: Papillary thyroid carcinoma (PTC) is the most frequent endocrine malignancy. Apart from genetics, autoimmunity has been implicated in its pathogenesis. In this context, we set out study the role of Pro- inflammatory cytokines in PTC in South Indian population.Material and methods: This prospective case-control study was conducted on surgically managed PTC patients. Institutional ethical committee approval was obtained. Diagnosis of PTC was ...

ea0081ep1015 | Thyroid | ECE2022

What is the ideal approach for thyroidectomy in a given patient? Proposal of an algorithm

Bangaraiahgari Ramesh , Bhargav Panchangam Ramakanth , Bangaraiahgari Rajesh , U Udaya Kumar , Mayilvaganan Sabaretnam

Introduction: Thyroidectomy can performed by open or wide array of endoscopic techniques. Lack of uniform consensus on specific indications for each technique leads to confusion on ideal thyroidectomy technique. In this context, we analysed our experience with specific emphasis on deducing an algorithm on ideal technique for a given patient. Material and methods: This is a retrospective study conducted at a tertiary care endocrine surgery department in S...