Endocrine Abstracts

Vitamin D deficiency has a leading role in endothelial functions and pathogenesis of type two diabetes and is supposed to take part in atherosclerosis. In this study we aimed to investigate the correlation between markers of atherosclerosis and inflammation with 25(OH)D levels in patients with type two diabetes. Forty patients with type two diabetes and macrovascular complication and 40 patients without macrovascular complication were included in the study. Thirty healthy subj...

Introduction: Primary hyperparathyroidism (PHPT) is associated with increased risk of mortality from cardiovascular disease and this appears to decrease with time after parathyroidectomy. However, data on hyperparathyroid patients are conflicting and there is no data regarding secondary hyperparathyroid patients. Our aim in this study was to determine the association between flow-mediated dilatation (endothelium dependent, FMD), nitroglycerine-induced dilatation (endothelium i...

Introduction: Coagulation and fibrinolysis defects were reported in primary hyperparathyroid(PHPT) patients. However, there is not enough data regarding platelet functions in this group of patients. Platelet functions of hyperparathyroid patients were measured in very few studies and they have conflicting results. Our aim was to evaluate the platelet functions in primary and secondary hyperparathyroid(SHPT) patients and to compare it with the healthy subjects.<p class="abs...

Introduction: Recent studies indicate that patients diagnosed with adrenal incidentaloma may present with cardiovascular disease. The aim of this study was to investigate markers of subclinical cardiovascular disease in patients with adrenal incidentaloma and healthy control group.Methods: This study included 50 patients with non-functional adrenal adenoma and 30 healthy controls. BMI and waist circumference of the patients were measured. The lipid param...

Introduction: Prolactinomas are the most common pituitary tumors. Macroadenomas are rarely seen. Dopamine agonists such bromocriptin and cabergoline are the preferred treatments for prolactinomas. Herein, we report a patient with macroadenoma whose adenoma has resolved rapidly with cabergoline treatment.Case: A 49 year old male patient evaluated for weakness and headache. After detection of central hypothyroidism he was referred to our department. His pr...

A lactating 31-year-old woman who developed L5 vertebral compression fracture 2 months after the delivery of her first child is presented. Serum concentrations of Ca was 10.24 mg/dl (8.6–10.2 mg/dl), phosphorus was 4.1 mg/dl (2.7–4.5 mg/dl), albumin was 4.6 mg/dl, ALP was 210 U/l (35–105 U/l), PTH was 13.8 pg/ml (15–65). There was axial osteoporosis, as assessed by dual-energy X-ray absorptiometry. Z score; L1 (−3), L2 (−3.8), L3 (&#872...

Background: Paget’s disease may affect as many as 3% of adults older than 40 years of age; it is often asymptomatic and usually progresses slowly. Paget’s disease affects men and women almost equally, but men tend to be more symptomatic. The disease is usually not clinically apparent until age 50–60 years. It usually progresses slowly and does not develop in new sites. Many different bones can be affected, and the lesions can vary from single, monostotic lesions...

Aim: Low BMD and atherosclerosis may share similar underlying biological mechanisms including higher serum phosphate and inflammation. Neutrophil-lymphocyte ratio (NLR) as a simple marker of inflammation. There are scarce data indicating improved atherosclerosis and cardiovascular events with biphosphonate and teriparatide therapy. We aimed to evaluate NLR before and after 6 months of teriparatide therapy in patients with severe established osteoporosis....

Introduction: An update of health economics analysis of diabetes mellitus (DM) in Turkey was performed. The primary objective was to collect and calculate the healthcare resources utilized for the management of DM.Methods: Thirty-one out of 40 randomly chosen centers completed the study. Medical files were reviewed for the data recorded for at least two years prior to the study. Collected data included laboratory tests, treatments, inpatient/outpatient f...

Primary hyperparathyroidism during pregnancy is a rare condition associated with a high frequency of complications in both mother and fetus. Operation in the second trimester is offered. Here we report about a case with hyperemesis and hyperparathyroidism during routine laboratory examinations.A 30-years-old pregnant woman attendant our policlinic with hyperemsis gravidarum. Her calcium and parathormone level were elevated; 11.6 mg/dl and 135 pg/ml, resp...