Endocrine Abstracts

Herein, we present a case of a 68-year-old woman who had hyperthyroidism and a large mass lesion in the upper portion of her right lung. The patient had a history of previous subtotal thyroidectomy 40 years before. A few years after the operation she noticed some enlargement on her neck. Two years before the admission she was evaluated for some unrelated complaint and a large mass was discovered on her right lung on X-ray examination and she was considered to have a lung cance...

Objective: We aimed to investigate the short term effects of atorvastatin on endothelial function and oxidized LDL (oxLDL) levels and to evaluate the association of endothelial dysfunction to oxLDL levels and inflammatory markers in type 2 diabetic patients.Material and methods: After ethical committee approval thirty type 2 diabetic and 11 healthy subjects with LDL levels between 100–160 mg/dl. Without a history of cardiovascular event were include...

ACTH-independent micronodular adrenocortical hyperplasia is a rare cause of Cushing syndrome. In some forms of micronodular adrenal disease, darkly pigmented micronodules are seen in the presence of atrophy of the peripheral adrenal tissue. In most cases of pigmented micronodular hyperplasia Carney complex is associated with the disease. Here, we present a case of Cushing syndrome due to sporadic primary pigmented micronodular hyperplasia not accompanied by Carney complex....

Both hyperhomocysteinemia and increased inflammatory activity are shown to be associated with atherosclerosis. But, the relation of inflammatory activity to homocysteine levels is not well established. In the present study, we aimed to evaluate the relation of plasma homocysteine (tHcy) levels to atherosclerotic vascular disease and inflammatory activity in type 2 diabetic patients.Ninty type 2 diabetic patients were included in the study. Forty one of t...

Introduction: Obesity represents a major public health challenge and is linked with increased risk of multiple medical conditions including atrial fibrillation (AF). We have recently published the study protocol of the ‘The Effect of complex weigHt-reducing interventiOns on rhythm control in oBese subjects wITh Atrial Fibrillation’ (HOBIT-AF) trial. Here we communicate the preliminary results with the focus on the use of smart technologies and telemedicine.<...

Introduction: Adrenocortical carcinoma (ACC) is a rare disease with a poor prognosis. In recent years, two prognostic scoring systems incorporating relevant clinicopathological features of ACC (ENSAT stage, grade, resection status, age at diagnosis, tumour symptoms) have been proposed: the GRAS and S-GRAS scoring systems. The prognostic value of these systems has been demonstrated in large, multicentre studies.Aim: To su mmarize the clinicopathological f...

Acromegaly is a rare disease associated with hypersecretion of growth hormone due to adenoma of somatotroph cells in the pituitary gland, with elevated morbidity and mortality. Acromegaly and thyroid diseases show high co-occurrence. In our study; we aimed to determine the relationship between disease activity at the time of admission and after treatment with the presence of goiter, presence of nodules, and possible accompanying thyroid malignancy in 119 patients with acromega...

Acromegaly is a rare disease with high morbidity and mortality associated with excessive secretion of growth hormone due to adenoma of somatotroph cells in the pituitary gland. In patients with acromegaly, residue may remain after surgical treatment, and disease control is attempted with surgery, medical treatment or radiotherapy for these patients. Pituitary imaging, IGF-1 and GH measurement are used in the follow-ups. Dynamic Contrast Enhancement perfusion MRI provides infor...

In the present study, we aimed to investigate the efficiency of ultrasound-guided fine-needle aspiration biopsy in our clinic. Totally, 701 patients followed at Department of Endocrinology, Faculty of Medicine, Eskisehir Osmangazi University with nodular thyroid disorder were included in this study during January 2000 and January 2011. Ultrasound-guided thyroid fine-needle aspiration biopsy was performed in these 701 cases at Interventional Radiology Department. Throid nodules...

Empty sella (ES) is characterized by herniation of the subarachnoid space within the sella, compression and flattening of the pituitary gland. Stretching of the pituitary stalk may also be seen. Empty sella is a frequent finding (5–23%) in autopsy series while it is < 0.01% in persons who undergo medical attention. Meanwhile there is an increase in sellar emptiness with age. Regarding pathophysiology and etiology, it may be primary to the incompetence of the diaphrag...