Endocrine Abstracts

A 51 yr old woman presented to ENT surgeons with nasal polyps. Since examination revealed a multi-nodular goitre, large hands and prognathism, acromegaly was suspected. MRI of the pituitary arranged, was normal. Two years later, nasal polyps returned. CT on this occasion showed evidence of polyps with sinusitis but again a normal pituitary fossa. She was referred to a rheumatologist for carpal tunnel symptoms, the features of acromegaly were rediscovered and she was referred t...

Objective: We sought to assess the knowledge of adrenal insufficiency among undergraduate healthcare students and pharmacy staff.Methods: We undertook a cross-sectional UK-wide survey of final year undergraduate student knowledge of AI before and after an online educational intervention. Universities were recruited through the Council of Medical Schools, Council of Pharmacy and Dean of Health Council, whereby surveys wer...

Primary hyperparathyroidism (PHP) is a common endocrine condition. The associated metabolic abnormalities are usually amenable to surgical treatment (PTX). Although it is generally believed that such treatment will reduce the risk of long-term complications this has not been demonstrated in a clinical trial and the current treatment guidelines are based on consensus. In order to assess the effect of parathyroidectomy on two of the most common complications of PHP, renal stones...

The rising prevalence of childhood obesity is a major public health concern. Approximately 21% of children by the age of eleven are clinically obese, with a further 14% classed as overweight. The causes of obesity of childhood obesity are multifaceted, leading to a complex multi-disciplinary management approach. A high proportion of children and young people do not meet the recommended guidelines of a minimum of 60 minutes physical activity per day. In addition to the barrier&...

Background: Patients with hypoparathyroidism may present acutely with hypocalcaemia and these patients may have multiple admissions; however, data on the incidence of acute and recurrent acute hypoparathyroidism are scarce in the literature.Aim: We wished to determine: (1) the causes of severe hypocalcaemia amongst A&E attendances (2) the incidence of acute hypocalcaemia due to hypoparathyroidism amongst A&E attendances, and (3) the incidence of ...

Background: The Turner Syndrome Life Course Project, UCLH, has collected data on 810 women with TS, attending clinic for 20 years and has accumulated over 8000 clinic visits. We present an analysis of the effects of timing and type of exogenous oestrogen on health outcomes in adults.Methods: A cross- sectional analysis of 475 subjects with primary amenorrhoea with accurate age of pubertal induction data was performed using correlation coefficients contro...

Background: Patients with hypoparathyroidism may present acutely with hypocalcaemia and these patients may have multiple admissions; however, data on the incidence of acute and recurrent acute hypoparathyroidism are scarce in the literature.Aim: We wished to determine: (1) the causes of severe hypocalcaemia amongst A&E attendances (2) the incidence of acute hypocalcaemia due to hypoparathyroidism amongst A&E attendances, and (3) the incidence of ...

Background: The Turner Syndrome Life Course Project, UCLH, has collected data on 810 women with TS, attending clinic for 20 years and has accumulated over 8000 clinic visits. We present an analysis of the effects of timing and type of exogenous oestrogen on health outcomes in adults.Methods: A cross- sectional analysis of 475 subjects with primary amenorrhoea with accurate age of pubertal induction data was performed using correlation coefficients contro...

Background: Local guidelines for infants born to mothers with a history of thyrotoxicosis previously recommended that infants were observed in hospital until thyroid function tests were checked on day 4, with follow up on day 10, causing inconvenience to families and unnecessary cost to services. Following a literature search, our revised local guidelines recommend low-risk infants can be discharged on day 0 without follow up, stratified using maternal TSH-receptor antibody (T...

Introduction: The current Endocrine Society guidelines (2010) recommend biochemical and radiological evaluation of men with HH to ascertain underlying hypothalamic and/or pituitary aetiology although the cost-effectiveness of this strategy is yet to be established. We did a retrospective audit to ascertain epidemiology, management and diagnostic outcomes for men with HH in our hospital practice against the current Endocrine society guidelines.Methods: A ...