Endocrine Abstracts

Introduction: Most brand-name drugs do not differ that much from their generic counterparts, so switching between the two is not an issue. Levothyroxine, however, is an exception. The question of generic equivalency of levothyroxine products has remained unanswered for several decades. The purpose of the present study was to learn whether there is a difference of dosage between brand-name and generic levothyroxine in patient with well controlled primary hypothyroidism<p cl...

Introduction: Treatment of primary hypothyroidism relies on a daily intake of levothyroxine, which dosage is determined first by the weight then by TSH levels monitoring. The daily dosage can vary with the cause of the hypothyroidism and the weight. The aim of our study was to determine if the adherence was a factor influencing the dosage of levothyroxine in a group of well-controlled hypothyroid patients.Method: We performed a cross-sectional study incl...

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine disease in women of childbearing age. This condition combines, according to the diagnostic criteria of the Rotterdam consensus 2003, clinical and/or biochemical signs of hyperandrogenism, oligo- and/or anovulation and polycystic ovaries detected by ultrasound. Thyroid diseases are also frequent in the general population. The aim of our study was to determine the prevalence of thyroid ultrasound alterations in...

Introduction: Darier disease, also known as dyskeratosis follicularis, is a rare autosomal dominant genodermatosis characterized by a persistent eruption of keratotic papules. It is caused by mutations in the ATP2A2 gene encoding sarcoendoplasmic reticulum Ca 2+ -ATPase isoform 2 in the endoplasmic reticulum. Since it is expressed in most tissues, other organs besides the skin may be involved in Darier disease. In this case, we report a patient treated for Darier disease who w...

Background: Obesity is an expanding pathology in the world and in Tunisia. We conducted this study to assess the thyroid function in a population of obese women and to investigate the relationship of thyroid status parameters with clinical and metabolic parameters.Methods: This is a cross-sectional retrospective study about 50 obese women carried out at the obesity unit of department A of the National Institute of Nutrition in Tunis. We collected body ma...

Introduction: Parathyroid carcinoma is an uncommon cause of primary hyperparathyroidism. It is responsible of 0.4% to 5% of all cases of primary hyperparathyroidism. Parathyroid carcinoma has a high probability of local recurrence, regional node and distant metastasis and the preoperative diagnosis is challenging.Case presentation: We report a case of a 66-year-old female patient with medical history of hypertension and chronic kidney failure. She was di...

Introduction: Nowadays, social media has become a valuable source of health-related information which can have an important impact on people’s behaviors and decisions regarding their diseases. To improve management of diabetes, patients often seek health information in social media platforms, including Youtube. We aim in this review to analyse factors associated with the popularity of videos found on YouTube that adress diabetes management.Methods: ...

Background: The risk of myocardial infarction among patients with type 1 diabetes is, in addition to traditional cardiovascular disease risk factors, associated with duration of diabetes, reduced glycemic control and renal complications. However, the specific cardiovascular risk predictor models for type 1 diabetes mellitus are subject to many limitations and aggressive macrovascular disease can rarely happen at an early age.Case Presentation: We report ...

Introduction: Nowadays, social media has become a valuable source of health-related information which can have an important impact on people’s behaviors and decisions regarding their diseases. To improve management of diabetes, patients often seek health information in social media platforms, including Youtube. However, the nature of its content, which anyone can upload, isn’t always reliable and scientifically accurate, sometimes even misleading. The aim of this stu...

Introduction: Diabetes is a disease affecting quality of life of millions of persons worldwide. Instagram is one of the most successful social media network. It influences, via its posts, thoughts, emotions and decision making of many topics, including health related ones. The aim of this review to analyse the emotional sharing content of diabetes related posts in Instagram.Methods: An Instagram query using the search term “diabetes” i...