Endocrine Abstracts

In the present study, we aimed to investigate the efficiency of ultrasound-guided fine-needle aspiration biopsy in our clinic. Totally, 701 patients followed at Department of Endocrinology, Faculty of Medicine, Eskisehir Osmangazi University with nodular thyroid disorder were included in this study during January 2000 and January 2011. Ultrasound-guided thyroid fine-needle aspiration biopsy was performed in these 701 cases at Interventional Radiology Department. Throid nodules...

Congenital adrenal hyperplasia (CAH) owing to 21 hydroxylase deficiency (21OHD) is an inherited autosomal disorder characterized by diminished glucocorticoid and aldosteron biosynthesis. Partial 21OHD leads to the classical simple virilizing form, characterized by prenatal virilization of external genitalia in female fetuses without salt wasting. Ambiguous genitalia in a genetically female infant is frequently due to CAH. The uncertainty about the sex of a newborn is often inc...

Hashimoto thyroiditis (HT) is the most common cause of hypothyroidism in the world with iodine deficiency and its incidence is 0.3–1.5 per 1,000. The aim of this study is to retrospectively evaluate the demographic characteristics, clinical and laboratory findings of the patients with HT who applied to our endocrinology outpatient clinic. The findings were compared with the control group who had hypothyroidism with negative thyroid autoantibodies. For this purpose, a tota...

Primary hyperparathyroidism during pregnancy is a rare condition associated with a high frequency of complications in both mother and fetus. Operation in the second trimester is offered. Here we report about a case with hyperemesis and hyperparathyroidism during routine laboratory examinations.A 30-years-old pregnant woman attendant our policlinic with hyperemsis gravidarum. Her calcium and parathormone level were elevated; 11.6 mg/dl and 135 pg/ml, resp...

Seckel syndrome (SS) is described as the prototype of the primordial bird-headed type of dwarfism (Seckel 1960). It represents a spectrum of multisystem abnormalities. We present a case of SS and discuss the possible effects of IGF-1 and IGF-3 in the development of growth failure, type 2 Diabetes Mellitus (DM) and severe insulin resistance (IR).Case: A 21-year-old female was referred to our clinic because of growth retardation and amenorrhea. At birth, s...

Herein, we present a case of a 68-year-old woman who had hyperthyroidism and a large mass lesion in the upper portion of her right lung. The patient had a history of previous subtotal thyroidectomy 40 years before. A few years after the operation she noticed some enlargement on her neck. Two years before the admission she was evaluated for some unrelated complaint and a large mass was discovered on her right lung on X-ray examination and she was considered to have a lung cance...

Seckel syndrome (SS) is a rare disorder of severe growth retardation and craniofacial-skeletal abnormalities. In scant number of reports, neonates had intact hypothalamic–pituitary–adrenal axis before they die because of cardiopulmonary abnormalities. We present an unique case of SS at the age of 18 years and discuss the possible explanations of his growth retardation and sex reversal.Case: A 18-year-old female presented with short stature and ...

Aims: In this study, we examined the relationships between levels of adipocytokines and traditional and non-traditional cardiovascular risk markers in patients with type 2 diabetes mellitus (T2DM).Methods: Serum leptin, resistin, adiponectin, visfatin, high sensitive C-reactive protein (hsCRP), homocystein, asymetric dimethylarginine (ADMA), fasting glucose, insulin, glycated haemoglobin (HbA1C) and full lipid and lipoprotein profile, systolic...

ACTH-independent micronodular adrenocortical hyperplasia is a rare cause of Cushing syndrome. In some forms of micronodular adrenal disease, darkly pigmented micronodules are seen in the presence of atrophy of the peripheral adrenal tissue. In most cases of pigmented micronodular hyperplasia Carney complex is associated with the disease. Here, we present a case of Cushing syndrome due to sporadic primary pigmented micronodular hyperplasia not accompanied by Carney complex....

Introduction: Pituitary apoplexy (PA) is a clinical emergency resulting from acute ischemia or bleeding of the pituitary gland. Complaints of patients are usuallay headache and vision problems. We tried to discuss the reasons for presentation, pituitary imaging and hormones of patients.Patients and Methods: 10 patients (5 men and 5 women), median age 53 years at diagnosis were retrospectively reviewed. FSH, LH, estradiol/testosterone, GH, IGF1, TSH, FT4,...