Endocrine Abstracts

Objective: To study the usage of oral antidiabetic drug (OAD)s prescribed to T2DM patients by General Practitioners and to compare overall glycaemic status of different OAD users at the time of referral to a tertiary care clinic.Methodology: T2DM patients attending a referral clinic underwent a proforma-based interview on their first visit. Data regarding subjects’ ongoing prescription (at least for preceding 3 months with a compliance rate ≥8...

Objective: Despite an increase ininsulin utilization in India over the past 10 years, wide variation exists in injection practices and usage across the Indian geography. This cross-sectional study was designed to audit various aspects of insulin usage, tolerability and efficacy of insulin regimens, degree of variability in injection techniques and its causes, interactions, and associations with glucose control and other outcomes.Methods: Data for th...

Introduction: There is a general assumption that glycemic control in persons with diabetes(PWD) has deteriorated since the onset of COVID-19 pandemic. We conducted this to compare the glycemic status of a very large cohort of PWD prior to COVID-19 outbreak with that of a similar cohort post onset of the outbreak. Methods: This was a retrospective study wherein entire data of glycated hemoglobin (HbA1c)% available in the hospital database since 3rd Octobe...

Background: Serum C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are useful indicators of inflammation in patients with sub-acute thyroiditis. Despite the widespread use of several diagnostic tests, the purpose of this study was to compare the usefulness serum CRP and ESR in deciding which patient requires of glucocorticoid therapy.Methods: A total of 28 patients with sub-acute thyroiditis, included in this study. Serum CRP and ESR mea...

Objective: Diabetic mastopathy (DMP) is an uncommon fibrous disease of the breast, most commonly found in premenopausal women with type 1 diabetes exposed to long-standing insulin therapy. Often mimicking breast cancer clinically and on imaging, this condition poses a diagnostic challenge requiring pathological confirmation.Case presentation: A 68-year-old woman with type 1 DM and a family history of breast cancer in paternal aunt had an abnormal screeni...

Here we present a case of follicular thyroid cancer with elevation of thyroglobulin (Tg, in ng/ml) detected almost 10 years after initial surgery and radioactive iodine therapy (RAI). The elevated Tg persisted for years before he was found to have a metastasis in his kidney 16 years after his initial cancer treatment. A 78 year old male had a total thyroidectomy followed by RAI therapy in 2001 for a 2.4 cm follicular thyroid cancer. His Tg became mildly elevated in 2009, and c...

Introduction: Intra thyroidal parathyroid adenoma is an uncommon presentation of primary hyperparathyroidism (PHPT). Herein we report such a patient who had recurrent hypercalcemia after a classical parathyroid exploration.Case presentation: 45 year old female, home-maker had a long standing history of weakness, back and lower limb pain, loss of appetite. Preliminary evaluation at secondary care level revealed hypercalcemia (18.3 mg/dl) with high intact ...

Objective: IMPROVE study was designed to assess the safety and effectiveness of NovoMix30® in type 2 diabetes subjects under normal clinical practice conditions.Methods: This large multi-national, open label, prospective, 6 month long observational study captured data for above 50 000 patients started on NovoMix30® with/without oral anti-diabetic drugs (OADs)/other insulin. This paper analyses safety data of 17 995 patient...

During pregnancy progressive maternal insulin resistance occurs which is normal, ‘sparing’ glucose that can be transported across the placenta to be used by the fetus. In gestational diabetes mellitus (GDM) maternal glucose dysregulation is exacerbated, characterised by hyperglycaemia and associated with long-term adverse outcomes in mother and child, such as increased risk of diabetes and/or cardiovascular disease in later-life. Continuous glucose monitoring (CGM) i...