Endocrine Abstracts

Despite advances in neurosurgical techniques, due to their size and their readily invasive nature, surgical resection of functional or non-functional pituitary macroadenomas is often only partial, justifying the use of any additional treatment (resumption of surgery, radiotherapy, treatment drug).Patients and Methods: 10 patients were included in the study (7 men middle-aged 56 and 3 women middle-aged 48). 4 patients followed for non-functional pituitary...

Craniopharyngioma is a slow growing benign epithelial tumor, growing from the pituitary stalk or pituitary gland in the sellar and/or parasellar region. Despite its benignity, the quality of life of patients is most often altered, due to the endocrine, visual and neuro-intellectual sequelae linked to the tumor itself and/or its treatment, as well as a high rate of recurrence. local. Early diagnosis remains the determining factor in prognosis. The objective of this study is to ...

Introduction: Pituitary somatotrop adenomas are very rare in children and adolescents. They are supposed to be more invasive (invasion of cavernous sinuses or meninges±compression of adjacent neural structures) than adults’ones. We aimed to analyze their characteristics, and their complications.Patients and subjects: are studied subjects whose clinical symptoms began before 20 years old. They all had biological, hormonal, ophthalmological, radi...

IntroductionBardet–Biedl syndrome (BBS) is a rare autosomal recessive ciliopathy characterized by rod-cone dystrophy, learning difficulties, polydactyly, obesity, genital malformations, and renal abnormalities. We report the case of a young patient followed for this syndrome, which is revealed by early obesity.ObservationThis is a 23-year-old patient from a consanguineous marriage with a personal history...

Introduction: Bilateral adrenal tumours are rare and account for 10–15% of adrenal lesions. They can be infectious, inflammatory, tumour, hémmoragiques, and genetic. The clinical and imaging used to guide diagnosis.Aim: Assess clinical, etiologic, and therapeutic characteristics of bilateral adrenal masses.Population and methodology: This is a retrospective study of the records of patients with bilateral adrenal masses co...

Introduction: Congenital adrenal hyperplasia (CAH) are genetic diseases with a deficit of one of the enzymes of steroidogenesis (21 hydroxylase OH, 90%). The consequences of the adrenal hyperandrogenism that results are observed when the treatment is not undertaken precociously.Aim: To study the impact of CAH and or treatment by glucocorticoids on the final size and gonadal function in girls.Materials and methods: 25 patients with ...

Introduction: Intra-testicular adrenal inclusions (ISIT) are benign tumors made of ectopic adrenal cortex tissue hyper stimulated by ACTH in excess. All pathologies causing a rise ACTH levels may be associated with adrenal inclusions. They are found mainly in patients with congenital adrenal hyperplasia (CAH) of untreated or poorly treated.Objective: Search the frequency of ISIT in CAH and clarify clinical and progressive characteristics.<p class="ab...

Introduction: Malignant phaeochromocytomas are rare tumours, developed at the medulla and paraganglia. Their diagnosis is established by the presence of metastases of organs devoid of chromaffin tissue or by the appearance of neoplastic recurrence. They are characterized by a morbidity and mortality due to the effects of uncontrolled and important hypersecretion cathécolaminergique and resistance to conventional cancer treatments.Aim: Report the obs...

Introduction: Impact of suppressive therapy with LH RH analogues is more stop the premature pubertal development, reduce the acceleration of bone maturation that compromises the final size and avoid psychological disturbances caused by hormonal imbalance.Aim: To study the effects of treatment on pubertal development, bone maturation and evolution of the size during and at the end of treatment and final height in 20 patients with central precocious pubert...

Introduction: The inflammatoirs background processes, and infiltrating tumour of the pituitary stalk are rare. They are a heterogeneous group of lesions responsible of partial or global hypopituitarism.Aim: Search for thickening of the pituitary stalk aetiologies and specify the clinical aspects.Population methodology: This is a retrospective study of 24 patients with thickening of the pituitary stalk. All patients benefited from a...