Endocrine Abstracts

Post parthyroïdectomy hypocalcemia is a frequent situation, generally due to a definitive or transient hypoparathyroïdism.The ‘Hungry bone syndrome’, is a rare severe hypocalcemia etiology, assigned to an excessive osseous avidity, occurring in intense bone remodeling situations like fibrous osteitis or renal osteodystrophy.We report a case of a 41 years old woman, presenting a chronic renal failure, at hemodial...

Introduction: Pituitary apoplexy is caused by an infarction or a haemorrhage in a pituitary adenoma manifesting in acute headaches, consciousness impairment, endocrine features, and moderate to severe visual loss, with chiasmal syndrome or oculomotor palsies.Case report: We describe here a case of a 25 years old woman, followed in our institute for a Cushing disease, and who underwent a pituitary apoplexy 24 h after a standard low-dose dexamethasone supp...

The craniopharyngioma is a benign tumor, curable but aggressive by its localization involving the vital and visual prognosis of the patients. Treated mainly by surgery associated with radiotherapy which allows high long-term survival but at the expense of significant side effects, it nevertheless poses a problem of therapeutic management. The aim of this study is to illustrate the therapeutic difficulties in the management of craniopharyngiomaPatients an...

Introduction: Pituitary apoplexy is a rare and potentially life-threatening endocrine and neurosurgical emergency, most often linked to hemorrhage or necrosis of a pituitary adenoma.Observation: We report the case of a 45 year old patient, with a history of chronic headache, hospitalized in the emergency setting for the management of meningeal syndrome with severe headache associated with vomiting, a significant drop in visual acuity, exophthalmos and pt...

Medullary carcinoma of the thyroid (MCT) is a tumor developed at the expense of the thyroid parafollicular cells, and secretes the polypeptide hormone calcitonin. It is known as an aggressive tumor that metastasizes early. Case Report: We describe a case of a 57 year-old women, who presented a neck mass, for which she underwent a total thyroidectomy associated to a bilateral neck dissection and was diagnose as MCT. Post operatively calcitonin remained elevated (19000 pg/ml). C...

IntroductionThe diagnosis of primary hyperparathyroidism (PHP) is essentially biological. Current imaging techniques (ultrasound and scintigraphy) make it possible to locate an adenoma in the majority of cases. The objective of this study is to clarify the place of imaging in the topographic diagnosis of hyperparathyroidism.Patients and methodsThis is a retrospective study including 40 patients with PHP who h...

IntroductionOsteoporosis has generally been considered a female disease; this may explain why this pathology has focused less attention on men. While osteoporosis has been underestimated and poorly treated in female patients, the situation is even worse in male patients, despite the fact that up to one third of hip fractures are suffered by men.GoalTo assess the characteristics and risk factors associated wit...

IntroductionThe association between vitamin D deficiency and primary hyperparathyroidism( PHP) has clear implications. Co-existing vitamin D deficiency may cause the serum calcium level to fall into the normal range, which can lead to diagnostic uncertainty. The objective of this study is to assess the vitamin D status of patients followed for primary hyperparathyroidism.Materials and methodsThis is a retrosp...

IntroductionMarfan syndrome is a rare autosomal dominant genetic disease resulting from a mutation in the gene encoding type 1 fibrillin (FBN1), which is a glycoprotein in the composition of elastic fibers in connective tissue. It mainly affects the cardiovascular, musculoskeletal and ocular systems.Case presentationWe report the case of a 14-year-old girl, with no particular history, referred to an endocrino...

Introduction: Acromegaly is caused by chronic hypersecretion of GH and IGF-1. Chronically elevated GH and IGF-1 levels lead to a complex spectrum of signs.Objectives: To describe the clinical, hormonal and radiological profile of acromegaly at the time of diagnosis.Materials and methods: Retrospective study including 67 patients hospitalized in the Endocrinology Department of the EPH BologhineResults: There w...