Endocrine Abstracts

Introduction: Subclinical hyperthyroidism (SH) affects about 1% of population. The diagnosis of this disease leans on the laboratory criteria only: decreased of TSH and normal FT3 and FT4 levels. SH increases mortality mostly due to cardiovascular diseases including arrhythmia and overload of the heart. Enlarging of heart chambers is one of the cause of arrhythmia, and cardiac index is one of indicators of heart after load.Aim: To e...

Introduction: Lack of radioiodine uptake in differentiated thyroid carcinoma (DTC) is a big diagnostic and therapeutic problem. This sign is associated with worse prognosis. In NRADTC patients with elevated thyreoglobulin levels with no evidence of disease in radioiodine scintigraphy, scintigraphy with the somatostatin analog labeled with 99mTc seems to be an alternative imaging method.Aim: Assessment of scintigraphy with the somatostatin anal...

Background: Melatonin as strong antioxidant and free radical scavenger can play important, protective role in disease in which oxidative damage is a significant component e.g.: in coronary heart disease, neoplastic disease, neurodegenerative disease. The aim of our study was determination of the effect of melatonin supplementation on malonyldialdehyde (MDA) concentration and activity of: superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) in patients...

Introduction: Subclinical hyperthyreosis (SH) affects about 1.5% population at least. The diagnosis of this disease leans on the laboratory criteria only: decreased of TSH and normal FT3 and FT4 levels. SH increases mortality and there is no unequivocal procedure algorithm to manage patients with this desease.Aim: To estimate an influence of cure of SH on heart rate and on autonomous nervous sytem and to find the relationships between parameters of Holte...

Aim: Evaluation of efficacy and safety of thyroid artery embolization procedure as a method of treatment of hyperthyreosis.Patient and methods: Since May 2004 to July 2005 the thyroid artery embolization procedures have been performed in 9 pts (7 women and 2 men) in mean age 62.3 (44 – 77). The reason for such a treatment were: hyperthyroid goiter with the other organs compression in 5 cases, Graves disease in 2 and thyrotoxicosis type I after amiod...

Introduce: Lack of radioiodine uptake in Differentiated Thyroid Carcinoma (DTC) is a huge diagnostic and therapeutic problem. This sign is associated with worse prognosis. In patients with elevated thyroglobulin levels and with no evidence of disease on radioiodine scintigraphy, scintigraphy with somatostatin analogs can be an alternative imaging modality.The aim: Assessment of scintigraphy with the somatostatin analog 99mTc-HYNIC-TATE to visu...

Introduction: Lack of radioiodine uptake in Differentiated Thyroid Carcinoma is a huge diagnostic and therapeutic problem. This sign is associated with worse prognosis. DOTA-TATE preparation is a somatostatin analogue coupled with 90 Y which emites β (−) radiation. Its use in a treatment depends on excessive expression of somatostatin receptors (SSTR) in malignant tumours.The aim of the study: To present a possibility of treatment o...

Introduction: The patients with inoperable hormone - secreting pituitary tumours are treated with cold somatostatin analogues, but it is not always effective. DOTA-TATE preparation is a somatostatin analogue coupled with β (−) emitter 90 Y. The efficacy of the treatment is based on excessive expression of somatostatin receptors (SSTR) in these tumours.The aim of the study: To assess the feasibility of treatment of pituitary tumours ...