Endocrine Abstracts

Introduction: Insulin is widely used in Type 2 patients to control the blood sugar when the oral hypoglycaemic agents fail. This is a case report of a type 2 diabetes patient who developed Myocardial Infarction after factitious hypoglycaemia with insulin.Case report: A 64-year-old gentleman with known Ischaemic Heart Disease was treated with insulin (Mixtard 30) and metformin for his type 2 diabetes. He presented to diabetes Specialist nurse with persist...

Background: Maternal hyperthyroidism (MH) during late pregnancy is associated with adverse neonatal outcomes but the effects of MH in early gestation when managed in a specialised joint obstetric endocrine clinic setting is unclear. Objectives: To evaluate the obstetric and neonatal outcomes of maternal hyperthyroidism presenting during early gestation. Methods: Endocrine and obstetric record of 40 pregnancies with active hyperthyroidism managed in the antenatal endocrine clin...

Introduction: Hyponatremia from SIADH secondary to undiagnosed Myelomas are extremely rare and we present one such case.Clinical case: 63 year old woman with background of MGUS under regular haematology review/ILD/NAFLD/IHD presented with severe constipation on top of weakness, weight loss and tingling in the peripheral extremities. She was euvolemic on admission with Serum Sodium 124mmol/l, Potassium 4.3 mmol/l, Urea 3....

Background: Diabetic peripheral neuropathy (DPN) is considered to be the risk factor for the development of sarcopenia. Various previous studies showed the correlation between DPN and muscle disorders, but the study regarding the association between sarcopenia and nerve conduction parameters in diabetic peripheral neuropathy is limited.Aim: This study was planned to detect the association between sarcopenia with peripheral nerve functions in type 2 diabe...

64 y/o male was being investigated for raised PSA. Following an MRI and biopsy, he was diagnosed with high grade prostatic intraepithelial neoplasia requiring close PSA surveillance. Incidentally, he was found to have bilateral adrenal lesions, measuring 6.4 cm on the left and 4 cm on the right. Prior to review in endocrine clinic, adrenal workup and CT adrenals were performed. CT showed both adrenal masses contain fat and calcification and are thought to be bilateral adrenal ...

A 50 years old man was seen in the Endocrine clinic with elevated calcium (2.80 mmol/l, normal 2.20-2.60) and Parathyroid hormone (10.7 pmol/l, normal 1.6-6.9) levels. His medical background includes Alport Syndrome, Renal Allografts (1st 1990, 2nd 2000 and 3rd 03/11/2005), and Osteopenia on DEXA scan in February 2020. He did not have any renal stones in the past. There was no family history of hypercalcemia. He was on Vitamin D 1000 Units daily (Vitamin D 55 nmol/l, normal 50...

Introduction: Graves’ disease (GD) has a well-known association with thymic hyperplasia caused by TSHR expression in thymus and regresses by approximately 33-90% with treatment. Splenomegaly due to lymphoid hyperplasia has also been linked with GD in about 10% patients. Cerebral venous sinus thrombosis (CVST) linked with GD is documented in literature but is more common occurrence in solid cancers.Case presentation: We report a case of 32-year man a...

Background: With advances in radiological technology, the detection of incidentally discovered pituitary abnormalities is increasing, 90% being secondary to pituitary adenomas. Patient morbidity increases when these lesions are large enough to cause hormone insufficiency or visual field defects, highlighting the importance of appropriate management.Aim: To evaluate management of patients with pituitary incidentaloma in accordance with national guidelines...

Aim: To evaluate the feasibility of non-face to face (NFTF) contact in the follow-up for patients with thyrotoxicosis on carbimazole therapy.Background: While on carbimazole, achievement of a euthyroid state may involve multiple clinic appointments. We hypothesize by conducting these appointments in a NFTF setting, i.e. telephone consultation with trained nurse practitioner supported by an Endocrine consultant; a higher volume of consultations can occur ...

Introduction: NICE recommends weight loss surgery as a treatment option for people with obesity. However, long term data on outcomes and complications on surgery are limited. We report unexplained adrenal insufficiency post bariatric surgery.Case report: Patient one27 years old lady underwent Roux-en-Y gastric bypass (RYGB). Weight loss (kg) was from 130.2 to 73.2 over a 2-year period. Patient complained of general unwell and dizzi...