Endocrine Abstracts

Introduction: Mauriac syndrome (MS) is considered a glycogenic hepatopathy characterized by growth failure, delayed puberty, hepatomegaly with abnormal liver enzymes, hypercholesterolemia. These features were attributed mainly to insulin deficiency and sub-optimal diabetic managementCase report: 18 years old male, presented with short stature and delayed puberty. The patient was diagnosed to have type 1 DM at the age of 6. He was on a premixed insulin re...

Introduction: The normal development of the female reproductive tract depends on the interaction between genetic, hormonal and environmental factors for the differentiation of the Müller Wolff ducts, and the urogenital sinusCase report: 16-year-old female, single, school student presented to our endocrine department complaining of delayed puberty. The patient was delivered by normal vaginal delivery, no history of anosmia or hearing defects There is...

Very low calorie diets (VLCD) have been a time-honored means of losing weight for many decades. The DiRECT trial has put VLCD back in the limelight and now NHS England and Scotland have committed resources to piloting VLCD as an intervention for Type 2 diabetes. Is this premature, or is it the solution for the tsunami of Type 2 diabetes that we face? Prof Tricia Tan and Dr Abd Tahrani will debate the utility of VLCD in the treatment paradigm of Type 2 diabetes....

Background: Obesity and thyroid neoplasia are common endocrinological diseases in the world and Iraq, and risk factors of this cancer are usually unmodifiable but there are some evidences that obesity is associated with increasing prevalence of many malignancies due to proposed pathophysiological mechanisms. Numerous research assessed the connections between thyroid disease outcomes and obesity, but only a small number took TBSRTC into account. The relationship between obesity...

Aim: To determine the incidence of hypocalcaemia and the need for calcium supplementation after thyroid surgery in 120 patients.Methods: A prospective study to determine the incidence of hypocalcaemia by measuring ionized calcium level in 120 patients underwent thyroidectomy at King Abdul Aziz University Hospital, the data included pre- and post-operative ionized calcium level, albumin, free thyroxine, thyrotopin and alkaline phosphatase. As well include...

Background: Diabetes is a risk factor for both PAD and PAD-associated mortality. Diabetic patients have worse arterial disease and a poorer outcome than nondiabetic patients. Fetuins are blood proteins made in the liver more abundant in fetal blood. Fetuin-A is regarded as an inhibitor of systemic calcification.Aim of this work: To assess the relationship between plasma fetuin-A levels and peripheral vascular disease in type 2 diabetes mellitus.<p cl...

Introduction: Iodine is needed for the production of thyroid hormone. The prediction of iodine intake is difficult. The standard measure of iodine nutrition in a community is the median urinary iodine excretion, expressed in micrograms per liter. According to the WHO, a median urinary iodine excretion of 100–199 μg/l indicates that the iodine intake is adequate.The aim of this work is to measure the iodine excretion in patients with thyroid nod...

Insulin is a thyroid growth factor that stimulates proliferation of thyroid cells in culture. It has been observed that insulin receptors are over expressed in most thyroid tumors as an early step in thyroid carcinogenesis.Eighty women (mean age 36.85±4.71 years) were evaluated by a thyroid ultrasound (US), fasting plasma insulin and HOMA IR. Subjects were divided into four groups as follows: G1 (n: 24),subjects with IR and obesity; G2 (n<...

Background: Diabetic retinopathy (DR) is a clinically well-defined sight-threatening complication in type 2 diabetes. Angiopoietin 1 (Ang1) has been shown to promote endothelial cell survival without causing proliferation, stabilise endothelial interactions with surrounding support cells and can block the vascular permeability effects of vascular endothelial growth factor (VEGF). More recent data suggest that balance between these growth factors may affect vascular endothelial...

Introduction: In 2013 Trouillas et al. reported a new prognostic clinicopathological classification of pituitary adenomas. This classification analyses the impact of the intensity of proliferation and invasiveness of the tumor on patients’ prognosis. The aim of the study was to review this new classification in giant pituitary adenomas (GPAs) treated with endoscopic transsphenoidal approach.Material and methods: The study is a retrospective...