Endocrine Abstracts

Objective: Thyroid nodules are common in the population more than 90% are benign. Data about the long-term follow-up of benign nodular thyroid disease is limited. We aimed to clarify, clinical outcome, frequency and magnitude of volume changes in cytologically and/or sonographically benign nodules in long-term(> 5 years) follow-up and to determine the predictive features of nodule growth.Methods: We retrospectively collected data of cytologically and...

Aim: The aim of this study was to determine the malignant potential of thyroid nodules with macrocalcifications and to evaluate the role of other sonographic findings in the diagnosis of malignancy in thyroid nodules besides macrocalcifications.Method: The findings of 8250 patients who applied to our outpatient clinic and underwent thyroid ultrasonography(US) between 2008 and 2021 were retrospectively reviewed. We included a total of 303 patients with 30...

Background and aim: Ethnic differences in testosterone concentrations may account for variation in the prevalence of androgen-mediated disorders amongst different racial groups. Previous reports in middle-aged subjects have either found no differences, or a lowered TT and calculated free testosterone (CFT) in South Asian (SA) compared with Caucasian men. In light of this uncertainty and to exclude any confounding influence of age we sought to determine the effect of ethnicity ...

Objective: The objectives of this study were to determine the prevalence of diagnosed and undiagnosed diabetes mellitus (DM), prediabetes and to evaluate the associated risk factors in the sample of adult Turkish population.Methods: A total of 4000 eligible study subjects aged 20 years or older, chosen by multistage sampling on a field were selected. Of those 3721 subjects (2139 women and 1582 men) participated in the study. The study was performed betwe...

Introduction: The aim of this study was to validate the American Thyroid Association (ATA) risk of recurrence staging system (2009).Methods: Retrospective analysed 300 adult (239 women, 61 men) differentiated thyroid cancer patients followed for a median of 57 months (range 38–97).Results: ATA risk stratification of patients according to the system 54.7% low-risk, 39.7% moderate risk, and 5.7% were in the high risk group. The ...

Introduction: Diabetes insipidus (DI) is a disease characterized by excessive thirst, polydipsia and excess diluted urine caused by insufficiency of antidiuretic hormone or renal resistance to its effect. Although it is generally a benign condition, severe hypernatremia and hypertonicity may cause death if water loss is not compensated.Case report: A 72-years-old man admitted to our clinic for routine control. In medical history, he told that when he was...

Background: Adrenal carcinoma is rare endocrine cancer. Survival time is short and primary treatment is surgery.Methods: Four patients with histopathologically diagnosed as adrenal carcinoma between 2007 and 2013 were evaluated retrospectively.Results: Two of the patients were female and others were male. Their ages were 39, 50, 55 and 61 respectively. All the patients were admitted to the hospital with abdominal pain. Tumor diamet...

Obesity is a risk factor for calcaneal spur (CS) formation which is supposed to originate from chronic plantar fasciitis. But histological findings support the thesis that ‘plantar fasciitis’ is a degenerative fasciosis without inflammation. Diabetes mellitus may contribute to the risk of CS by decreased ability of tissue repair and increased reactive ossification. Thus, we aimed to determine CS incidence in asymptomatic obese subjects with and without type 2 diabete...

BackgroundTo date, numerous molecular tests have been developed for preoperative evaluation of thyroid nodules. Nevertheless, these tests cannot be administered in many centers due to their imprecise diagnoses and high costs. The present study aimed to investigate the effect of making surgical decisions in a council through a multidisciplinary approach after clinical, ultrasonographic, and pathological evaluation of nodules on the accuracy of the decisio...

Background: Isolated growth hormone deficiency (IGHD) is a condition associated with the growth failure of children due to deficient growth hormone (GH) production and action. IGHD occurs in 1/4000 to 1/10 000 births and the most of cases are sporadic and idiopathic. Between 5 and 30% show familial pattern, suggesting a genetic etiology of disease. Mutations on GH-1 gene lead to growth failure and cause IGHD disease.Objective: Purpose of our research was...