Endocrine Abstracts

Introduction: Current guidelines for the management of asymptomatic primary hyperparathyroidism (A-pHPT) recommend that 25-hydroxyvitamin D levels should be assessed in all patients and vitamin D deficiency (VDD) should be cautiously corrected. It is unknown whether VDD affects the probability to meet surgical criteria currently proposed for A-pHPT. Aim of study was to evaluate whether VDD recognition affects the probability to meet surgical criteria in A-pHPT patients.<p ...

Introduction: It has been reported that vitamin D deficiency is common in patients with primary hyperparathyroidism (pHPT), and this could affect the clinical expression of the disease. However only few studies addressed this issue and refer to American or North European patients. In these studies, only about one third of the patients showed a vitamin D replete state.Subjects and methods: In 207 consecutive pHPT patients (M/F=45/162, age (mean ±<sma...

Introduction: Primary hyperparathyroidism (pHPT) is characterized by an increased frequency of glucose tolerance abnormalities associated with insulin-resistance. Few studies evaluated the relationship between insulin resistance and others cardiovascular risk factors in pHPT.Subjects and methods: In 255 consecutive pHPT patients (M/F=66/189, age (mean±S.D.): 59.9±13.7 years, PTH: 215.6±219.4 pg/ml, calcium: 11.2±1.2 mg/...

Thyroid cancer is the most common endocrine malignancy, and accounts for between 5 and 10% of thyroid nodules biopsied in endocrine services. As per the Global Cancer Observatory, the incidence of thyroid cancer in Bahrain is 2.12 cases per 100 000 people, which is less than the neighbouring countries of Saudi Arabia and Kuwait. The purpose of the study is to investigate the relationship between thyroid cancer and obesity in Bahrain, where 28.9% of males and 38.2% of females a...

Objective: We sought to assess the knowledge of adrenal insufficiency among undergraduate healthcare students and pharmacy staff.Methods: We undertook a cross-sectional UK-wide survey of final year undergraduate student knowledge of AI before and after an online educational intervention. Universities were recruited through the Council of Medical Schools, Council of Pharmacy and Dean of Health Council, whereby surveys wer...

Contexte: Acromegaly is a rare disease, usually caused by hypersecretion of growth hormone (GH) by a pituitary adenoma and very rarely by ectopic secretion of GHRH. It remains a serious disease reduces life expectancy because of its cardiovascular and metabolic impact.Objective: The objective of this study is to report the glycemic profile in patients followed for acromegaly in the endocrinologic center of CHU Med VI of Marrakech.P...

Contexte: Kallmann syndrome is a rare genetic disease which can affect both men and women. It combines hypogonadotropic hypogonadism which characterised by a failure to start or to fully complete puberty naturally; olfactory disorders such hyposmia or anosmia, impaired color vision, deafness, unilateral or bilateral renal aplasia and midline anomalies.Objective: We report a case of this rare syndrome, responsible of delayed puberty view of infertility.</...

Case history: We present the case of a 64 year old man with an incidental finding of pituitary macroadenoma (1.1×0.8×0.5 mm). He had a past medical history of obstructive sleep apnoea, asthma, osteoarthritis, hypertension, retinal detachment and cataract.Investigations: Blood tests.Results and treatment: Pituitary function tests showed markedly elevated prolactin 4272 mIU/L (86–324), elevated free tri-iodothyronine (...

Introduction: Growth hormone deficiency is a rare cause of stunting; its diagnosis is often delayed by severe growth retardation; confirmed by non-response to GH stimulation tests (insulin and glucagon-propranolol test). The absence of early diagnosis and treatment can lead to severe growth retardation. We propose to determine the prevalence of different etiologies of growth hormone deficiency in patients followed for a saturo-weight delay at the Arrazi Hospital, Medical Unive...

Introduction: Necrosis of the nasal pyramid is mainly of traumatic origin, among the other possible causes, those induced by systemic diseases, in particular Wegener’s granulomatosis…We report a case of necrosis of the nasal pyramid secondary to prolonged intubation in a type 1 diabetic.Observation: Patient T.T, 28 years old, followed for a poorly balanced type 1 diabetes, admitted to a blood clot in a table of diabetic ketoacidosis. The patie...