Endocrine Abstracts

Context: Cystic adenomas of the parathyroid gland are relatively rare, with an estimated incidence of 0.3-1.5% of all parathyroid tumors. These tumors are benign and typically present as a single cyst or multiple small cysts within a solid nodule. Due to their rarity and nonspecific imaging features it may be challenging to diagnose preoperatively. However, the diagnosis is confirmed by fine-needle aspiration (FNA) biopsy and pathological examination of the tissue obtained by ...

Congenital Adrenal Hyperplasia (CAH), a genetic adrenal gland disorder, can disrupt hormonal balance, leading to fertility issues in females. Timely interventions, like hormone therapy, are essential for managing fertility concerns and ensuring a safe pregnancy for individuals with CAH. A 28-year-old patient consulted an endocrinologist for a detailed examination due to infertility issues persisting for 2 years. Prior to this, the patient had given birth to a 22-week-old newbo...

Introduction: The purpose of this study was to evaluate effectiveness of somatostatin analog (SSA) treatment in patients with acromegaly.Methods: The study involved retrospective data collection from charts of 29 patients with acromegaly who received medical therapy at Vilnius University Hospital Santariskiu klinikos in 2016.Results: Patient population consisted of 10 males (34.5%) and 19 females (65.5%), mean age 58±26 years....

Introduction: Poorly differentiated carcinoma (PDTC) is an aggressive and rare form of thyroid carcinoma that originates from follicular cells and accounts for only 1-3 percent of all thyroid carcinomas diagnosed1. Most of the limited instances of PDTCs have been observed in older individuals. Instances in the pediatric population are exceedingly rare2.Case report: This report refers 17-year-old female, who presented moderate hirsut...

Introduction: Follicular thyroid carcinoma (FTC) is the second most common malignancy of the thyroid gland. Distant metastasis, usually in bones or lungs, can be found in about 10%–15% of cases. A clinical case of FTC distant bone metastasis is presented.Case: A 62-year-old male came to endocrinologist for annual follow-up (FU) of multinodular goiter, euthyreosis in 2010. Two years before prostate carcinoma (T1N0M0) was also diagnosed for the patien...

Objective: Misclassification of type 1 (T1DM) and type 2 diabetes mellitus (T2DM) is quite common and crucial to choice of appropriate therapy. The aim of the study was to evaluate the correspondence of islet antigen-2 (Anti IA2) and glutamic acid decarboxylase (Anti GAD65) antibodies with clinical diagnosis.Methods: The Anti IA2 and Anti GAD65 were measured in 583 patients (337 males and 246 females) diagnosed with T1DM or T2DM with not typical manifest...

Introduction: The purpose of this study was to evaluate treatment options and effectiveness in patients with acromegaly.Methods: The study involved retrospective data collection from charts of 75 patients with acromegaly who was treated at Vilnius University Hospital Santaros klinikos.Results: Patient population consisted of 21 males (28%) and 54 females (72%), mean age at diagnosis 52 ± 13 years. In most of the cases, macroad...

Introduction: Hypothyroidism is associated with a spectrum of symptoms affecting almost all bodily functions. We present a case of severe hypothyroidism with multiple body cavity effusions, volvulus of sigma creating ileus.Case report: A 70 year old female was admitted to emergency department with dyspnea, and acute abdominal pain. Physical examination was notable for anasarca, abdominal fluid wave, lower extremity pitting edema, hypotension. She did not...

Introduction: Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy. For the majority of patients with PTC, the prognosis is very good; however, up to 20% of patients suffer disease recurrence. Currently, the risk stratification for PTC recurrence is based on clinicopathological features which have limited prognostic value. Identification of molecular biomarkers of PTC recurrence such as protooncogene BRAF and miRNAs may help to improve risk-stratifie...

Introduction: ACTH producing macroadenoma and pituitary apoplexy are rare in Cushing’s disease. Somatostatin receptor agonist Pasireotide is indicated for the treatment of patients with Cushing’s disease for whom surgery is not an option or has failed. We present a case of pituitary apoplexy in patient with recurrence of Cushing’s disease treated with Pasireotide.Case: 38 years old female presented with quick weight gain, weakness, irregul...