Endocrine Abstracts

Introduction: Cortisol level measurement is required in the diagnosis and management of adrenal, pituitary and hypothalamic pathologies.Aim: The aim of this study was to evaluate clinician’s practice in ordering cortisol test.Methods: A retrospective study concerning 63 cortisol requests data collected by the laboratory computer system (Health Lab) between January 2024 and February 2024. Only requests of 0800 hours plasma cort...

Introduction: Inappropriate laboratory test utilization can result in unnecessary patient testing and increased healthcare costs. Thyroid-stimulating hormone (TSH) is recommended as the first-line test for investigating and monitoring thyroid dysfunction. We evaluate Thyroid function tests (TFTs) ordering in our hospital practice.Methods: A retrospective descriptive study included 400 TFTs requests. TFTs of interest were: TSH and FT4. These tests request...

Introduction: Hyperprolactinaemia can be caused by physiological changes, medications, pathological conditions, or can be idiopathic. The aim of this study was to evaluate clinicians's practice in ordering prolactin (PRL) test.MethodsA retrospective study concerning 75 prolactin requests data collected by the laboratory computer system (Health Lab) during January 2024. We collected age, sex and ordering's origins. PRL tests were performed based on electrochemiluminescence immu...

Introduction: Hepatocyte nuclear factor 1A MODY (HNF1A-MODY) is the most common form of Maturity-onset diabetes of the young (MODY) diagnosed in adults. It is caused by heterozygous mutations in the HNF1A gene and is associated with progressive β-cell failure and increasing hyperglycemia due to reduced insulin secretion. HNF1A-MODY is characterized by a large phenotypic variability. We herein report the case of a 40-year-old diabetic woman who was identified as h...

Introduction: Congenital hypopituitarism is considered a study model to understand the mechanisms of development and the physiological functioning specific to the pituitary gland. Its exact prevalence is challenging to establish. In this report, we present the experience of the endocrinology department at Hedi Chaker University Hospital in Sfax regarding the diagnosis and management of patients with antehypopituitarism associated with growth hormone deficiency (GHD).<p cla...

Introduction: Diabetes mellitus is a major public health problem affecting all ages worldwide. In Tunisia, 18% of the population has diabetes mellitus. In fact, it is one of the first ten causes of death in our country.Therefore, self-management education for diabetic patients play an important role in reducing diabetes complications and mortality rate. The education is conducted not only by doctors, but also by nurses.Purpose: The aim of this study is t...

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrinopathy caused by inappropriate PTH secretion by the parathyroid glands, which leads to alterations in phosphocalcic metabolism. The aim of our study is to determine the prevalence of complications of PHPT.Materials and Methods: Retrospective descriptive study of 83 patients with primary hyperparathyroidism collected over a period of 07 years (between 2015 and 2022) in the endocrinology ...

Authors: Mohamed Coco, Katrina Sheikh, Basheir Osman, Jayadave Shakher: Department of Acute Internal Medicine, Birmingham Heartlands Hospital-University Hospitals BirminghamIntroduction: Although skeletal metastatic diseases have commonly been associated with hypercalcemia; we present a case of severe hypercalcemia secondary to extensive skeletal sclerotic metastatic disease.Case: ...

Introduction: Cushing’s disease is a rare condition observed in about 8–10% of patients with pituitary tumor. In the majority of cases, corticotroph adenomas are small, intrasellar and less than 10mm in diameter, while macroadenomas occur in 4–10% of the patients. An observation of two clinical cases is reported. The observationCase number 1: a female patient aged 31, hospitalized for suspected Cushing’s dis...

Autoimmune thyroiditis (AIT) is a group of inflammatory thyroid disorders with either hyperthyroid, euthyroid or hypothyroid state. The aim of this study is to detect the subclinical thyroiditis among the Egyptians type 1 diabetic patients and to study the relation of the thyroid antibodies to different metabolic control indices of diabetes. The study group consisted of 50 type 1 diabetic patients aged from 8 to 18 years. They were selected from the out-patient daily clinics o...