Endocrine Abstracts

Pancreatic neuroendocrine tumors (PNETs) are uncommon neoplasms from the endocrine pancreas, whose incidence is recently rising. Unfortunately, an advanced stage is often found at diagnosis; thus, identification of new molecular diagnostic, prognostic, and therapeutic markers is required. Ghrelin and somatostatin/cortistatin systems are two multifunctional regulatory complexes widely distributed throughout multiple tissues, including the pancreas, where they exert diverse (pat...

Pancreatic neuroendocrine tumors (panNETs) are the second most common neoplasm of the pancreas. panNETs arise from cells of the pancreatic islets and comprise a diverse and heterogeneous group of neoplasms. This hampers their systematic study, and the identification of common molecular signatures that might facilitate a better diagnosis of the disease, and the development of efficient therapeutic approaches. Indeed, there are no clinical, biochemical, anatomopathological, immu...

Introduction and objectives: Hyperglycemia is a common problem in hospitalized patients, that increases infections, mortality, costs and the hospital stay. The objective of this study is to know the prevalence of hyperglycemia in our hospital.Methods: We designed a cross-sectional observational study. We included patients admitted in the hospital every 3 days in 2 months. We excluded patients younger than 15 years, stays less than 3 days and those of the...

Introduction and objectives: Hyperglycemia (HG) is a common problem in hospitalized patients that increases infections, mortality, costs and the hospital stay. The objective of this study is to know the association of the HG with cardiovascular risk factors (CVRF), stress factors, hospital stay and mortality.Methods: We designed a cross-sectional observational study. We included patients admitted in the hospital every three days in two months. We exclude...

Introduction and objectives: Hyperglycemia (HG) is a common problem in hospitalized patients that increases infections, mortality, costs and the hospital stay. The objective of this study is to know the association of the HG with cardiovascular risk factors (CVRF), stress factors, hospital stay and mortality.Methods: We designed a cross-sectional observational study. We included patients admitted in the hospital every three days in two months. We exclude...

Introduction and objectives: Hyperglycemia is a common problem in hospitalized patients that increases infections, mortality, costs and the hospital stay. The objective of this study is to know the management and control of hyperglycemia in our hospital.Methods: We designed a cross-sectional observational study. We included patients admitted in the hospital every three days in two months. We excluded patients younger than 15 years, stays less than three ...

Introduction: The use of radioiodine is a common treatment for differentiated thyroid cancer. However, special care should be exercised in treating patients who are on hemodialysis, due to the renal elimination of the radionuclide, which implies several technical difficulties and safety concerns. We have previously described the procedure and the short-term outcome and safety in three patients (Jimenez et al, Thyroid 2001; 11(11):1031–1034). Our results showed that the ra...

Background and aims: The prevalence of gestational diabetes (GDM) increases worldwide with rates between 9 and 35%. The management of GDM is a labor-intensive discipline, in which the global increase in GDM prevalence poses challenges to maintain high-quality care. A valuable solution could be the organization of group education. The ELENA study therefore aimed to evaluate women’s satisfaction about (group) education and treatment, their knowledge about GDM and whether th...

Pancreatic neuroendocrine tumors (panNETs) comprise several neoplasms in which a precise diagnosis and therapeutic treatment are hampered by their diversity and heterogeneity which in turn, hind the identification of common molecular signatures and the development of efficient therapeutic approaches. Subsequently, there are no clinical, biochemical, anatomopathological, immunohistochemical or molecular features capable to currently predict either tumor prognosis or post-surgic...

IntroductionDysregulation of alternative splicing is emerging as a new hallmark of cancer. This dysregulation may originate from mutations and/or altered expression of specific components of the splicing machinery. Indeed, our group has shown that the expression profile of the splicing machinery is altered in several types of cancer, including endocrine-related cancers. However, to date, the status of alternative splicing and its putative dysregulation h...