Endocrine Abstracts

Introduction: Obesity is a component of eating disorders grouped under several eating disturbances due to emotional problems. Eating habits are directly influenced by eating disorders. Eating disorder rates in obese patients are reported to be 15-50% in various populations. This study aimed to evaluate obesity related eating habits (OREH) in obese patients who followed in an obesity center.Methods: A total of 752 (F/M: 636/116, 42.6±11.6 yrs ) obese p...

PurposeObesity, diabetes mellitus, and metabolic syndrome (MetS) have been known to be associated with increased skin autofluorescence (SAF). In patients with MetS, higher SAF measurements were found to be associated with an increased number of the components of MetS. In this cross-sectional study, we aimed to evaluate the association of MetS and its’ components with skin autofluorescence in severely obese patients and to examine whether diabetes or...

Introduction: Although medullary thyroid cancer (MTC) constitutes 2–4% of all thyroid cancers, it is associated with higher mortality compared to differentiated thyroid carcinomas. Here we present long term clinical results of medullary carcinoma patients’ follow-up in our center.Methods and results: MTC was detected in 27 (3.73%) patients of 850 thyroid cancer cases who were followed-up between 2004 and 2020 at the Marmara University School ...

Introduction:Acromegaly is caused by excess levels of growth hormone (GH) and insulin-like growth factor 1 (IGF1), which usually result from a pituitary adenoma. At the presence of classical symptoms, the diagnosis is confirmed by increased serum IGF1 concentrations and high serum levels of GH that are not suppressed in an an oral glucose tolerance test (OGTT). A nadir GH cut-off of 0.4 µg/lwith ultrasensitive assays is considered as diagnostic. How...

Osteoporosis in men is recently recognized as a major underestimated public health problem. In 2050, the incidence of hip fracture in men is expected to increase by 310% worldwide. After the age of 50, one out of three osteoporotic fractures are seen in men. Men suffering any major fracture have a higher mortality rate than women osteoporotic fractures. Screening is usually recommended in many guidelines above the age of 65 or 70 years and those younger aged with risk for oste...

Introduction: Inferior petrosal sinus sampling for ACTH is the current gold standard test for the differentiation of pituitary Cushing disease from the ectopic ACTH syndrome. Early studies with İPSS reported a diagnostic sensitive and specificity approaching 100%, additional experience has shown a false negative rate of 1-10%. This has been due to either technical problem with unsuccessful petrosal sinus catheterization or anomalous venous drainage of the pituitary. The ...

Levels of thyroid hormones may effect the levels of the glycation product and those of the oxidation products.Objective: To evaluate the relationship between skin autofluorescence (SAF), and serum advanced glycation end products (AGEs) parameters in hypothyroid and hyperthyroid patients.Method: Newlydiagnosed or untreated 100 overt and subclinical hypothyroid patients (42±13 yrs) and 50 overt-subclinical hyperthyroid patients ...

Introduction: Acromegalic osteopathy is an emerging complication characterized by high risk for vertebral fractures (VFS), whereas bone mineral density (BMD) may not be useful to predict the risk. Recent studies have reported that increased advenced glycation end products (AGEs) are associated with bone fragility. We aimed to evaluate the relationship between AGEs and VFs in patients with acromegaly.Study design: Cross-sectionalPat...

PurposeInferior petrosal sinus sampling (IPSS) is the gold standard test for the differentiation of pituitary Cushing disease from the ectopic ACTH syndrome (EAS). The measurement of prolactin during IPSS can be helpful to improve the accuracy of the procedure. We aimed to evaluate the effect of measuring prolactin levels as a predictor for the accuracy of IPSS procedure and evaluate its’ impact on the lateralization of adenoma.<p class="abstext...

Bariatric surgery patients are at risk of decreasing in muscle mass, vitamin and protein deficiency. The aim of this study is to asses muscle strength, serum protein and vitamin levels after bariatric surgery.Methods: 264 patients underwent bariatric surgery who completed 6 th month policlinic visits were included in the study. Patients were followed appropriately supplemented protein and vitamins as suggested; all study parameters were assessed before a...