Endocrine Abstracts

Objective: To study the peculiarities of the composition in patients over 50 years old.Materials and Methods: The study involved 136 adults aged 50 to 82 years. All subjects underwent complex examination, which included anthropometry (height, weight, body mass index (BMI)) and body composition analysis using Inbody 770 (Inbody Co.Ltd., Korea). Statistical processing of the results was performed using MedCalc Statistic software.Results: women’s age w...

Introduction: One of the objectives of weight loss in obesity is to prevent metabolic disorders. An important component in the maintenance of the achieved results is a change of eating behavior.Goal: To study the effect of liraglutide 3.0 mg on the dynamics of metabolic parameters and eating behavior in patients with obesity.Materials and methods: The study enrolled 42 obese patients in whom anthropometric parameters, metabolic par...

Objective: The aim of our study was to evaluate the possibility of maintaining the metabolic effects of liraglutide 3.0 mg treatment after it’s cessation.Methods: The study included 8 patients with type 2 diabetes (T2D) and obesity who received liraglutide 3.0 mg daily for 9 months. All of them successfully reduced body weight, insulin resistance level (IR), volume of visceral adipose tissue, HbA1c level. After discontinuation of liraglutide in 2019...

Introduction: Deficiency of growth hormone (GH) in children is manifested by pronounced stunting (below −2 sigmal abnormalities (SD)), different changes in body composition. Frequency of occurrence varies from 1:4000 to 1:10000 newborns.Objective: To assess the effectiveness of treatment by comparing the dynamics of growth of those with isolated growth hormone deficiency (IGHD) and of those with panhypopituitarism (PHP).Mater...

Introduction: There are a lot of conditions associated with human immunodeficiency viri such as lipodystrophy, fat atrophy, insulin resistance, low levels of high-density lipoprotein cholesterol, and hypertriglyceridemia. A diet program combined with exercises can help to treat patients with HIV.Methods: We used an online system for patient education based on video lessons, full of humor, pictures, and cartoons to convey the necessary information on good...

The aim of the study was to evaluate the risk of osteoporosis and related fractures in the patients treating in in-patient rehabilitation department.Methods: The survey was conducted by means of questionnaire of 600 patients aged >50 y.o. ordinary treated in in-patient department of rehabilitation center. Risk factors for osteoporosis were assessed using IOF “One-minute osteoporosis risk test”. 10-year probability of major osteoporotic fr...

Introduction: Liraglutide 3.0 mg could be effective option for obesity management. It is known that patients who have ≥5% weight loss in 16 weeks (‘early responders’ (ERs)) will have ≥10% weight loss in 56 weeks [1]. Predictors of this early response (ER) in 16 weeks are unknown.Methods: 22 obese patients (30% men; median age 40.0 [33.0; 48.5]) were recruited. The exclusion criteria were diabetes, psychotic disorders, obesity due ...

Objective: Assess the effectiveness of complex treatment of obesity with the use of orlistat (intestinal lipase inhibitor) on the knee OA (KOA) and the dynamics of cytokines (CRP, IL-6, TNF-α) depending on the degree of weight loss.Methods: 50 female patients (45–65 y.o.) with Kellgren-Lawrence stage II-III KOA and obesity (BMI > 30 kg/m²). Patients in Group 1 (n = 25) took 120 mg of orlistat 3 times a day in co...

Medical History of thirty five patients aged from one to sixteen years diagnosed with CAH have been analyzed in the Republican Center for Pediatric Endocrinology. Among the thirty five patients participating in the study (boys–fifty seven percent, girls –forty-three) seventy-one percent is with salt wasting form (SWF), twenty-two percent with virilising form (VF), three percent with non-classical form (NF). The mean weight SDS at birth is minus eight hund...

Objective: Sustained weight loss is a highly effective strategy to treat and prevent the development of type 2 diabetes (T2D). Bariatric surgery leads to significant weight loss, which ensures the achievement of remission of diabetes mellitus and other obesity-related comorbidities. AimThe aim of this study was to estimate glycemic profile of patients with morbid obesity and T2D after laparoscopic mini-gastric bypass (LMGB). MethodsWe conducted a retrospective study of ob...