Endocrine Abstracts

Introduction: Gestational Diabetes Mellitus (GDM) is associated with maternal and perinatal morbidity. Follistatin-like 1 (FSTL-1), also known as TGFB-beta-stimulated clone 36 (TSC-36), is a glycoprotein cardiokine reported to be associated with insulin resistance and inflammatory processes. To date, there is no study evaluating the effect of FSTL-1 gene polymorphism on the development of GDM in the literature. In this study, we aimed to investigate the effect of serum FSTL-1 ...

Diabetes Mellitus (DM) is, characterized by high blood glucose levels, one of the most common chronic diseases worldwide. In 2021, according to International Diabetes Federation, 537 million adults aged between 20 and 79 are diagnosed with DM. Environmental and genetic factors affect its etiopathogenesis. Disturbances in emotions or emotion regulation are regarded as a major contributor to the pathophysiology and etiology of the disease. People with DM who experience diabetes ...

Objectives: Subclinical hypothyroidism (SH) is characterized by normal serum free T4 (FT4), free T3 (FT3) levels and increased serum TSH levels. Endothelial dysfunction that is accepted an early step of the atherosclerosis, has been reported in patients with subclinical hypothyroidism. The aim of this study was to eveluate endothelial functions and the effect of L-thyroxine (L-T4) therapy on e...

Introduction: Thyroid nodules are common in population. High resolution ultrasound and fine needle aspiration biopsy (FNAB) are advised as the first line diagnostic methods. Bethesda classification system is used to provide standardization of cytologic reports. We aimed to evaluate ultrasound guided FNAB results in a mild-to-moderate iodine deficient city of Turkey.Methods: The patients (n=520), who underwent FNAB between December 2011 and Decem...

During the past decades, incidence of adrenal tuberculosis has been greatly decreased due to the introduction of antituberculosis drugs. It is reported that primary adrenal insufficiency (PAI) results from adrenal tuberculosis accounting for only 15%–20% patients in developed countries. Adrenal tuberculosis is the major cause of chronic PAI especially in developing countries. A 53 year old man presented with a 3 month history of generalized weakness, anorexia, weight loss...

ABSTRACT WITHDRAWN...

Background: Acromegaly which is caused by excessive growth hormone is a rare chronicle endocrine disorder. Because it is a rare disorder, limited data are available on the impact and consequences of acromegaly on the mental health of patients, but the investigations are growing over time.Aim: It aims to summarize the evidence identifying the mental health issues of patients with acromegaly.Methods: MEDLINE (PubMed), Web of Science,...

Scleredema diabeticorum is an infrequently seen connective tissue disorder that effects upper part of the body. The affected skin is thick, hard and painless. A 51-year-old male Type 2 diabetic patient was referred to our department for infected foot ulcer. On physical examination erythematous, hard, painless, wide-reaching skin lesion on his upper back and shoulders except from draining diabetic foot ulcer on his right foot first and second fingers. Multipl subcutanously insu...

Objective: To compare the impact of 4 surgical procedures (mini gastric bypass [MGB], sleeve gastrectomy [SG], ileal transposition [IT], and transit bipartition [TB]) versus medical management on gut peptide secretion, beta cell function, and resolution of hyperglycaemia in type 2 diabetes (T2DM).Research design and methodsA mixed-meal tolerance test (MMTT) was administered 6–24 months after each surgical procedure (mini gast...

Aim: The aim of the study was to determine the association between Hashimoto’s thyroiditis (HT) and differentiated thyroid carcinoma (DTC).Patients and methods: Seven hundred seventy two patients with thyroid nodular goiter who underwent fine-needle aspiration cytology (FNAC), followed up at Endocrinology and Metabolism out-patient clinic of Cerrahpasa Medical School, University of Istanbul between January 2000 and December 2010 were included retros...