Endocrine Abstracts

Introduction: Gestational Diabetes Mellitus (GDM) is associated with maternal and perinatal morbidity. Follistatin-like 1 (FSTL-1), also known as TGFB-beta-stimulated clone 36 (TSC-36), is a glycoprotein cardiokine reported to be associated with insulin resistance and inflammatory processes. To date, there is no study evaluating the effect of FSTL-1 gene polymorphism on the development of GDM in the literature. In this study, we aimed to investigate the effect of serum FSTL-1 ...

Traumatic brain injury (TBI) which is a worldwide public health problem has been recently recognized as a cause of neuroendocrine dysfunction. Pituitary dysfunction due to TBI may be partial or complete and in retrospective studies as many as 25–50% of patients have been demonstrated to have some degree of pituitary hormone deficiencies. Recently five prospective studies investigating the 12 months follow-up of anterior pituitary function after TBI have been published. Ba...

Introduction: We investigated the levels of IGF1 in acute myocardial infarction (AMI) and sought to determine whether a decrease might influence the long-term prognosis.Material and methods: Sixty-five patients who were admitted to our hospital with AMI were included in the study along with 26 other patients without coronary artery disease (CAD) who served as the control group. Fasting blood samples of all of the patients with AMI were obtained at the ho...

Introduction: Although the cause and effect relationship between the hypophyseal deficiency and osteoporosis is known well, the number of studies concerning bone mineral density (BMD) in patients with Sheehan’s syndrome (SS) are scarce. We aimed to investigate the relationship between BMD and deficient hormones in patients with newly-diagnosed Sheehan’s syndrome.Material and methods: Thirty-four patients with SS and age-gender-weight matched 22...

We report a case of 28-year-old girl with panhypopituitarism and ectopic neurohypophysitis due to absent pituitary stalk. She was admitted to endocrinology policlinic with short stature, growth retardation and primary amenorrhea. Basal hormones indicated tahat she has secondary hypothyroidism, adrenal insufficiency, hypogonadism and GH insufficiency. Peak cortisol response to the short ACTH test was normal but inadequate to insulin tolerance test. The other dynamic pituitary f...

Background and aims: It is reported that intracellular adhesion molecule-1 (ICAM-1) is important in autoimmune thyroid diseases also it is an important point that ICAM-1 level is high in postoperative hypothyroid cases. In literature, it is said that the level of plasma soluble ICAM-1 can be used as a evidence immune system activation and inflammation, and also it can be used for the diagnosis of some inflammatory and autoimmune diseases. The aim of our was to compare the leve...

Introduction: Papillary thyroid carcinoma (PTC) distant metastases without regional lymph node metastases are quite rare. Spinal cord teratomas are rare tumors mostly seen in children. To the best of our knowledge, the development of papillary carcinoma in intradural teratomas is theoretically possible, but has not been reported in literature.Case report: A 36-year-old female patient admitted with the complaint of drop foot. On MRI, 20x11x20.5 mm lesion ...

Introduction: Silent corticotroph adenomas (SCAs) are uncommon pituitary tumors, immunoreactive for ACTH, but without clinical evidence of hypercortisolism and present with local mass effects and some endocrine dysfunction. Case 43 years old male patient was diagnosed with pituitary tumor which was 5×3 cm in size. In history, 6 months ago he applied to another hospital with syncope and operated transsphenoidally. But these datas are unreachable. He had been suffering from...

Purpose: To determine the changes of the choroidal thickness (CT) in diabetes mellitus (DM) type 1 patients without clinical diabetic retinopathy (DR).Methods: We evaulated 50 patients with DM type 1 (50 eyes) and 50 healthy controls (50 eyes) in İzmir Military Hospital from January 2012, through January 2013. DR status was evaluated by indirect fundoscopy and included the study if they have no clinical diabetic retinopathy. Age, gender, duration s...

Introduction: Few studies have investigated the effect of gastric bypass surgery on lipid profile in obese patients with type 2 diabetes mellitus. We aimed to evaluate changes in lipid profile in obese diabetic patients undergoing Roux-en-Y gastric bypass (RYGB) surgery.Method: We retrospectively analysed 71 obese type 2 diabetic patients (46 women, 25 men) who underwent RYGB surgery. Weight, body mass index (BMI), total cholesterol (TC), high-density-li...