Endocrine Abstracts

Introduction: Of interest are cases of osteoporosis of unknown etiology after a recent delivery.Matherials and methods: A 33-year-old woman complained of frequent fractures of the bones of both feet (four times in the last year) after the birth of her third child. For the woman, this was the fourth pregnancy, according to her, after the birth of her second child, she had pain in the lower back, which aggravated with physical exertion (at 24 years old).</...

Background and Aims: When alcohol abuse and diabetes are combined, the consequences can be unpredictable and cause a double whammy, since both conditions cause similar pathological effects, in particular negative effects on the cardiovascular system.Methods: The patient is 49 years old, male. Height 175 cm, weight 95 kg. BMI 31.02 kg/m2. T2D was diagnosed 10 years ago. At the beginning of the disease, he took oral hypoglycemic drugs (can’...

Background and Aims: Arterial stiffness is associated with increased risk for target organ damage, cardiovascular events and overall mortality in the general population, patients with diabetes mellitus (DM) and patients with chronic kidney disease (CKD) of all stages. The aim of this study is assessment of pulse wave velocity (PWV) in patients with type 2 diabetes at different stages of diabetic nephropathy and without it.Materials and Methods: We examin...

Actuality: According to the International Classification of Sleep Disorders in type 2 diabetes, the risk of obstructive sleep apnea (OSA) in middle-aged people ranges from 18% to 36%. In a report by S. D. West et al. the incidence of sleep apnea in patients with diabetes is estimated at 23% compared with 6% in the general population. In a recent study, AS Peltier et al. it was found that 79.2% of patients with OSA had a violation of glucose tolerance and 25% were first diagnos...

Objective: To determine the effects of hypoglycemia while sleeping on somnological parameters for patients with type 1 DM.Materials and methods: The study included 57 person with type 1 DM (Group 1 – patients with blood glucose levels (BGL) during sleep <3.9 mmol/l; Group 2 – Patients with BGL – from 3.9 to 10.0 mmol/l. The examination included: daily monitoring of blood glucose by ‘CGMSGold’ (‘MedtronikMINIMED’ (US...

Objective: To establish the differences in terms of sleep for patients with type 1 diabetes, depending on the level of blood glucose levels (BGL) during the night.Materials and methods: The study included 43 participants with type 1 diabetes (Group A – patients with BGL during sleep from 3.9 to 7.4 mmol/l, Group B – 7.5–10.0 mmol/l. Patients had daily monitoring of BGL ‘CGMSGold’ by ‘MedtronikMINIMED’ (USA), polysomnogr...

It is determined that sleep apnea itself can affect the level of HbA1c, thereby affecting the compensation of carbohydrate metabolism in type 2 diabetes.Objective: To determine the quantity and type of sleep apnea in diabetes type 1, depending on the level of HbA1c.Materials and methods: The study involved 50 people with type 1 diabetes without the presence of diabetic autonomic neuropathy or diseases of the pulmonary system and EN...

Objective: Assessing the impact of glycaemic control on indicators of breathing during night sleep in type 1 diabetes patients.Methods: Continuous blood glucose monitoring by ‘SGMSGold’ (Medtronik MINIMED) with estimation of average glycaemic value (AG) and other parameters; polysomnographic monitoring by ‘SOMNOlab 2 (PSG) Polysomnography (R&K)’. Group 1 included patients with AG levels <8.0. Group 2: AG >8.0 mmol/l regard...

Study evaluates the impact of glycemia on the parameters of night’s sleep for patients with decompensated type 1 diabetes mellitus (T1DM).Materials and methods: A total of 21 cases with T1DM (HBA1C 8.5%). The monitoring of the average daily glycemia was performed through ‘SGMSGold Medtronik’ (USA) with estimation of average level of glucose (ALG). Patients divided into groups: group A – 10 patients with A...

The term “undifferentiated connective tissue disease” (UCTD) represents a stage of disease where clinical symptoms and serological abnormalities suggest autoimmune disease, but they are not sufficient to fulfill the diagnostic criteria of any well-established connective tissue disease (CTD). A 73-year-old man was referred to the 3rd hospital of Tashkent Medical Academy with signs of kidney lesion and the history of treatment at two other medical settings.<p cla...