Endocrine Abstracts

Visfatin/pre-B-cell enhancement factor is an adipocytokine, which is found in the visceral fat tissue and enhances the growth of precursor of B cells through showing synergy with IL7 and stem cell factors. Other cytokines released from the adipose tissue are TNFα and IL6, which has been shown to be related with pathogenesis of insulin resistance, diabetes, dyslipidaemia, inflammation, and atherosclerosis. Our aim was to determine the relationship of plasma visfatin/pre-B-...

Objective: Diabetic retinopathy was one of the important complications of diabetes both in type 1 or type 2 and cause blindness. High lipid levels was accused of endotheial dysfunction and so play a role in retinal exudate formation in retinopathy. The aim of this study was to acess the association between serum lipid levels and diabetic retinopathy.Methods: Our study was carried out retrospectively in Istanbul Medeniyet University Goztepe Training and R...

Objectives: Diabetic nephropathy is a common complication of diabetes. It can be a cause of abnormal lipoprotein metabolism and may be had an negative impact on metaboic control in diabetics. The aim of this study was to evaluate the effect of diabetic nephropathy on lipid profiles of adult type 1 diabetics.Methods: Our study was carried out retrospectively in Istanbul Medeniyet University Goztepe Training and Research Hospital between 2012 and 2013. The...

Differences in individuals’ eating habits affect adherence to diets and the weight management process. Identifying factors that influence the prevalence of obesity is crucial for addressing obesity-related health issues and implementing necessary preventive measures. This study aims to compare the changes in body composition resulting from medical nutrition therapy applied to individuals of Arab and Turkish origin seeking weight loss at a specialized clinic. Additionally,...

Objectives: Subclinical hypothyroidism (SH) is characterized by normal serum free T4 (FT4), free T3 (FT3) levels and increased serum TSH levels. Endothelial dysfunction that is accepted an early step of the atherosclerosis, has been reported in patients with subclinical hypothyroidism. The aim of this study was to eveluate endothelial functions and the effect of L-thyroxine (L-T4) therapy on e...

Introduction: Diabetes mellitus (DM) has been associated with abnormalities of cardiac function and left ventricular hypertrophy. Diabetic individuals, particularly women, had higher heart rates, greater left ventricular wall thicknesses, greater cardiac mass than unaffected subjects. We aimed to investigate association between waist circumference–body mass index (BMI) and left ventricle mass (LVM)-left ventricle mass index (LVMI), left ventricle myocardial perfusion inde...

Introduction: In recent years, interferon (IFN) is used in treatment of chronic hepatitis and the studies about the side effects of IFN therapy are increasing.Objective: We aimed to investigate the effects of IFN therapy on glucose metabolism.Materials and methods: Study group was consisted with 30 patients who were diagnosed as chronic hepatitis. Sixteen of 30 were chronic hepatitis B and 14 were chronic hepatitis C. Diagnose was ...

Aneurysmal subarachnoid hemorrhage has been reported to be associated with hypopituitarism. Also, internal carotid artery coil embolisation for aneurysmal hemorrhage is a rare cause of hypopituitarism. 58-year-old female patient who admitted to Emergency Department of Gazi University Medical Faculty due to visual loss and severe headache that did not respond to analgesics accompanied by nausea-vomiting starting 4–5 days ago. Sixth cranial nerve paralysis and bilateral tem...

Menopause defines the period in which women’s menstrual periods cease permanently, significant hormonal changes begin, and fertility is lost. In addition to the fact that menopause causes body weight gain, it has been found that body weight gain can negatively affect the menopausal process. In this study, the relationship between food consumption and body composition changes that may be caused by the menopause period and menopausal symptoms was investigated. In the study,...

Dipeptidyl peptidase 4 (DPP-4) is thought to play a role in the pathophysiology of metabolic and inflammatory diseases. Increased ADA activity has been suggested to induce insulin resistance and inflammation. We investigated DPP-4 and ADA activities, serum nitric oxide (NO) level and nitric oxide synthase (NOS) activity which are the oxidative stress parameters in patients with PCOS. Fifty two women with PCOS and 41 healthy women were included in this study. Serum ADA activity...