Searchable abstracts of presentations at key conferences in endocrinology

ea0035p753 | Obesity | ECE2014

Correlates of visceral and subcutaneous fat thickness in non-diabetic obese and morbidly obese patients

Gul Ozen Oz , Pekgoz Murat , Gullulu Sumeyye , Cander Soner , Tutuncu Ahmet , Seker Ismail , Sag Saim , Acikgoz Ebru , Sarandol Emre , Erturk Erdinc , Tuncel Ercan , Ersoy Canan

Objective: To determine the correlates of visceral and subcutaneous fat thickness in non-diabetic obese and morbidly obese patients.Methods: A total of 31 obese female outpatients composed of morbidly obese (n=16, BMI of ≧40 kg/m2) and obese (n=15, BMI of 30–39.9 kg/m2) patients were included in the present study. Data on age, anthropometrics, blood biochemistry, HOMA–IR, carotid intima-media thick...

ea0032p1103 | Thyroid cancer | ECE2013

Evaluation of whole-body scan, stimulated thyroglobulin after thyroxine withdrawal vs recombinant TSH administration according to the risk groups of tumor recurrence

Sahin Mustafa , Aydogan Berna Imge , Yuksel Bagdagul , Erdogan Murat Faik , Gullu Sevim , Emral Rifat , Corapcioglu Demet , Baskal Nilgun , Uysal Ali Riza

Background: Recombinant human thyroid-stimulating hormone (rhTSH)-stimulated serum thyroglobulin (Tg) (s-Tg) and (131)I whole-body scanning (WBS) are supposed to provide equal diagnostic information with thyroxine withdrawal (THW) at follow-up thyroid cancer patients without the symptoms of hypothyroidism. We aimed to compare the WBS and s-Tg levels after thyrogen injection and thyroid hormone withdrawal for tumor recurrence/persistance according to the risk groups.<p clas...

ea0020p93 | Thyroid | ECE2009

Current iodine status in Turkey

Erdogan Murat Faik , Agbaht Kemal , Altunsoy Tanju , Ozbas Sema , Yucesan Fatma , Tezel Basak , Sargin Canan , Ilbeg Ibrahim , Artik Nevzat , Kose Rifat , Erdogan Gurbuz

Surveys for the assessment of the iodine status, carried out between 1997 and 1999 in Turkey showed that the country was severe to moderately iodine deficient. (National median UIC 36 μg/l, goiter prevalence % 31.8). Therefore, a national IDD control program had been implemented and mandatory salt iodization were applied by July 1999 with 50–70 mg/kg KI or 25–40 mg/kg KIO3 to the household salt.Objectives: To evaluate the curren...

ea0020p94 | Thyroid | ECE2009

Results of the 2007 follow-up monitoring survey for iodine status in Turkey

Erdogan Murat Faik , Agbaht Kemal , Altunsoy Tanju , Ozbas Sema , Yucesan Fatma , Tezel Basak , Sargin Canan , Ilbeg Ibrahim , Artik Nevzat , Kose Rifat , Erdogan Gurbuz

Objectives: Assessment and monitoring which are two major components of a sustainable programme to eliminate IDD is being performed in Turkey since 1997. The initial survey, for the assessment of the iodine status, carried out between 1997 and 1999, showed that the country was severe to moderately iodine deficient (national median UIC: 36 μg/l, goiter prevalence % 31.8). Therefore, a national IDD control program had been implemented and mandatory salt iodization were appl...

ea0020p604 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

Results of acromegaly patients treated with surgery and/or somatostatin analog and/or radiotherapy in a University Hospital in Turkey

Demir Ozgur , Tonyukuk Gedik Vedia , Emral Rifat , Faik Erdogan Murat , Gullu Sevim , Corapcioglu Demet , Uysal Ali Riza , Baskal Nilgun , Kamel Nuri

Background: Transsphenoidal adenomectomy is the first choice of therapy, but about 50% of patients are not cured and require medical treatment and/or radiotherapy. We retrospectively analyzed the data on surgery, sandostatin analog therapy, radiotherapy and the combination of them.Materials-methods: The records of the 96 female and 70 male, totally 166 acromegalic patients who had been followed in Ankara University, Endocrinology and Metabolic Diseases D...

ea0020p666 | Reproduction | ECE2009

Periodontal disease in polycystic ovary syndrome

Dursun Erhan , Guncu Guliz , Cinar Nese , Harmanci Ayla , Ozbek Murat , Karabulut Erdem , Tozum Tolga F , Kilinc Kamer , Akalin F Alev , Yildiz Bulent O

Background: Periodontal disease (diseases of the tissues around teeth) and polycystic ovary syndrome (PCOS) are common disorders in women with a significant public health impact. Both disorders appear to be associated with diabetes and cardiometabolic risk. There are no published data regarding periodontal disease in PCOS.Objective: To determine periodontal status in women with PCOS compared to healthy women.Methods: We studied 25 ...

ea0014p396 | (1) | ECE2007

Vitamin D receptor gene polymorphisms: influence on bone metabolism in type 1 diabetic patients

Yavuz Dilek Gogas , Yazici Dilek , Yüksel Meral , Kiyici Sinem , Sert Murat , Sahin Ibrahim , Keskin Lerzan , Deyneli Oguzhan , Aydin Hasan , Tuncel Ercan , Akalin Sema

Patients with type 1diabetes mellitus are at higher risk of developing osteoporosis. Among the genetic factors related to the development of osteoporosis, a possible association between vitamin D receptor (VDR) gene polymorphism and bone mineral density (BMD) has been described in some populations.The aim of this study is to investigate the distribution of vitamin D receptor (VDR) polymorphisms and relation to bone turnover parameters and bone densitomet...

ea0011p357 | Diabetes, metabolism and cardiovascular | ECE2006

Relationship between plasma visfatin levels and the metabolic variables in metabolic syndrome

Sonmez Alper , Dogru Teoman , Tasci Ilker , Yilmaz Ilker , Pinar Murat , Naharci Ilkin , Bingol Necati , Kilic Selim , Demirtas Ayla , Bingol Sezin , Musabak Ugur , Ozgurtas Taner , Erbil Kemal , Erikci Selaha

Objective: Visfatin, a novel adipocytokine, is predominantly expressed in visceral fat and correlated with obesity. The pathophysiologic role of visfatin in metabolic syndrome (MS) is not clear. We aimed to investigate the relationship between plasma visfatin levels and components of MS, and also the effect of therapeutic lifestyle change (TLC) on these parameters.Design and methods: Nineteen patients (5 male, 14 female; mean age 51.0±9.3 years; bod...

ea0011p359 | Diabetes, metabolism and cardiovascular | ECE2006

The effect of fluvastatin on adiponectin and insulin sensitivity

Sonmez Alper , Dogru Teoman , Tasci Ilker , Yilmaz Ilker , Pinar Murat , Naharci Ilkin , Bingol Necati , Kilic Selim , Demirtas Ayla , Bingol Sezin , Musabak Ugur , Ozgurtas Taner , Erbil Kemal , Erikci Selaha

Objective: The pleiotropic functions of statins are crucial in reducing cardiovascular events. There is controversy about their effects on insulin resistance. The aim of this study was to investigate the effect of Fluvastatin treatment on plasma adiponectin and insulin levels in a group of dyslipidemic population who had no confounding factors for insulin resistance such as diabetes or hypertension.Design and methods: Forty nine (27 male, 22 female; mean...

ea0093oc26 | Oral communication 4: Pituitary and Neuroendocrinology | EYES2023

Whole blood transcriptomic signature of Cushing’s syndrome

Birtolo Maria Francesca , Armignacco Roberta , Benanteur Nesrine , De Murat Daniel , Guignat Laurence , Groussin Lionel , Libe Rossella , Letourneur Franck , Bertherat Jerome , Jouinot Anne , Assie Guillaume

Background: Cushing’s syndrome (CS) is associated with high morbidity and presents high interindividual variability. Easily measurable biomarkers, in addition to the hormone assays currently used for diagnosis, could better quantify the individual biological impact of glucocorticoids. The aim of this study is to identify such biomarkers through the analysis of whole blood transcriptome.Methods: Whole blood transcriptome was evaluated in 57 samples (...