Endocrine Abstracts

Introduction: Vitamin D in the human body plays a very important role.Aim: The aim of the study was identify the differences in concentration of 25OH vitamin D3 in blood and compared with anthropometrics and biochemicals results of researched group of people.Materials and methods: To research were included 212 patients hospitalized on Endocrinology Department of Hospital in Poland in 2012. Patients were divided into thre...

Receptor for advanced glycation end-products (RAGE) signalling, crucial for diabetic macroangiopathy, is also highly suspected to be involved in atherogenesis in the setting of preserved glucose metabolism.Aim: To determine the relationships between peripheral blood concentrations of RAGE agonists, namely amfoterin (HMBG1) and carboxy-methylo-lisine (CML) as well as RAGE inhibitor Endogenously Secretory RAGE (esRAGE), and the severity of atherosclerosis ...

Introduction: Insulin resistance (IR) and visceral obesity, elements of metabolic syndrome (MS), contribute to hyperandogenaemia and may lead to hirsutism and other signs of hyperandrogenism. Little is known about the influence of metformin therapy (MET) on hormonal profile in women with MS and IR without menstrual irregularity.Aim: To asses the influence of MET on sex steroids concentrations in young women with MS.Methods: The stu...

Introduction: Metformin (MET) is mainly used in diabetes mellitus type 2 (DM2) therapy. Little is known about its effects in patients with metabolic syndrome (MS) and insulin resistance (IR) without DM2.Aim: To asses the influence of MET on carbohydrate metabolism in young prediabetic women with MS.Materials and methods: The study population: 30 women with MS aged 25–45 years before (M1) and after (M2) ME...

Introduction: Metabolic syndrome (MS) is connected to atherogenic dyslipidemia. Data concerning influence of metformin (MET) therapy on lipid profile in nondiabetic women with MS remains unclear.Aim: To asses the influence of MET on selected lipid, apolipoproteins AI, B concentrations and atherogenic indexes values in young women with MS.Materials and methods: The study population: 30 women with MS aged 25–45 years before (M<s...

Pituitary abscess is a very rare entity, only 200 cases (mostly the complication of the pituitary surgery) has been described so far.We want to present the case of pituitary abscess arising from Rathke’s cyst.Case report: Seventy-years-old female treated due to clinical depression, was admitted to the Endocrinology Department because of profound hyponatremia (serum Natrium 119 mmol/l). She was diagnosed with plurihormonal ante...

It is a well-known fact that vitamin D has an impact on many tissues of human body. Recent studies showed that vitamin D deficiency has an influence on inflamation indicators in several endocrine diseases (for example PCOS, graves disease). The aim of the study was to demonstrate correlation between 25-OH vitamin D concentration and chosen inflammation indicators (C-reactive protein and insulin) in patients with non-functioning adrenal incidentalomas. Seventy-one patients hosp...

Abstract: Up to 96% of changes detected in adrenal glands are non-functioning adrenal incidentalomas. Adrenal masses are associated with increased risk of metabolic syndrome (MS). Studies demonstrate that new anthropometric parameters can be useful indicators of disturbances in glucose and lipid metabolism in various diseases. The purpose of the study was to determine antropometric parameters and its relationship with MS factors according to the criteria of the International D...

Backgroud: Though insulin resistance (IR) is common in polycystic ovary syndrome (PCOS), there is no agreement as to what surrogate method of assessment of IR is most reliable.Aim: We compared methods based on measurements of fasting insulin and either fasting glucose (HOMA-IR and QUICKI), or triglycerides (TAG) (McAuley index) with insulin resistance (Belfiore) index (IRI) derived from glucose and insulin during a 75-g oral glucose tolerance test (OGTT)...

Polycystic ovary syndrome is associated with lipid and carbohydrate metabolism disorders, leading to obesity and insulin resistance. The aim of the study was to asses the correlation among anthropometric parameters, metabolic markers (lipid and carbohydrate profiles) and CRP as inflammatory indicator in women with Polycystic Ovary Syndrome. The study consists of 43 women diagnosed with Polycystic Ovary Syndrome based on 2003 Rotterdam criteria. The patients were hospitalized i...