Searchable abstracts of presentations at key conferences in endocrinology

ea0063p470 | Calcium and Bone 2 | ECE2019

Successful management of tertiary hyperparathyroidism associated with hypophosphataemic rickets in an adult

Anagnostis Panagiotis , Tournis Symeon

Introduction: Chronic hyposphosphataemia is caused by increased concentrations of fibroblast-growth factor 23 (FGF23), mostly attributed to inactivating mutations of the phosphate-regulating endopeptidase homolog, X-linked (PHEX) gene. Secondary or tertiary hyperparathyroidism (THP) constitutes a rare complication of the disease, partly attributed to chronic supplementation of phosphate salts.Case presentation: A 31-year old woman was admitted to our dep...

ea0063p530 | Diabetes, Obesity and Metabolism 2 | ECE2019

Vitamin B12 and gestational diabetes mellitus

Kouroglou Eleni , Anagnostis Panagiotis , Daponte Alexandros , Bargiota Alexandra

Objective/Design: Gestational diabetes mellitus (GDM) has been associated with serious complications for both the pregnant woman and the newborn. Vitamin B12 is implicated in some important metabolic procedures such as methylation and one carbon cycle and its deficiency can cause serious health problems, such as hyperhomocysteinemia, defective synthesis of neurotransmitters and fatty acids and more. However, it is not known if there is a link between vitamin B12 deficiency and...

ea0049gp40 | Bone & Calcium Homeostasis 1 | ECE2017

Coexistence of primary hyperparathyroidism with papillary thyroid carcinoma: a case series

Anagnostis Panagiotis , Panagiotou Athanasios , Adamidou Fotini , Rafailidis Savvas , Kita Marina

Introduction: Primary hyperparathyroidism (PHPT) may rarely coexist with non-medullary thyroid carcinoma (NMTC). We report the clinical manifestation and management of nine cases of synchronous PH and NMTC.Cases: Eight women and one man were included (mean age at diagnosis: 64±6.6 years). In all cases, PH was the initial diagnosis, whereas NMTC was detected incidentally, after ultrasound assessment for PH. The histological diagnosis of NMTC was clas...

ea0049ep214 | Bone & Osteoporosis | ECE2017

Efficacy and safety of bisphosphonate discontinuation in postmenopausal osteoporosis: a systematic review

Anagnostis Panagiotis , Paschou Stavroula , Mintziori Gesthimani , Lambrinoudaki Irene , Goulis Dimitrios

Introduction: The maximum period of bisphosphonate use has not been determined, as their long-term appliance has been associated with adverse effects, such as osteonecrosis of the jaw (ONJ) and atypical femoral fractures (AFF).The aim of this study was to systematically present existent data regarding the effect of bisphosphonate discontinuation on fracture risk and bone mineral density (BMD).Methods/design: MEDLINE, Scopus, EMBASE...

ea0049ep827 | Thyroid (non-cancer) | ECE2017

Orbital disease primer for Endocrinologists-not always thyroid associated orbitopathy (TAO): a case vignette

Adamidou Fotini , Manani Christina , Anagnostis Panagiotis , Georgiou Thomas , Boboridis Kostas

Background: TAO is a rare disease, seriously involving 5% of patients with autoimmune thyroid disease. The clinical presentation may be difficult to distinguish from other orbital conditions.Case 1: A 63-year-old woman was admitted to the Neurology Service for worsening diplopia over the previous six months, with a working diagnosis of myasthenia gravis or multiple sclerosis. The Endocrine Service was consulted because of a long history of Hashimoto&#146...

ea0041ep197 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2016

Effects of gender and menopausal status on serum apolipoprotein concentrations

Anagnostis Panagiotis , Stevenson John , Crook David , Johnston Desmond , Godsland Ian

Introduction: Inconsistent data exist as to whether menopause is associated with increased cardiovascular disease (CVD) risk. However, few studies have evaluated differences in apolipoprotein metabolism according to menopausal status and gender. The aim of this study was to investigate the effects of gender and menopause on serum apolipoprotein B (apoB), A-I (apoA-I) and A-II (apoA-II) concentrations.Methods/design: A cross-sectional analysis was underta...

ea0035p167 | Calcium and Vitamin D metabolism | ECE2014

Unusual case of intrathyroid parathyroid hyperplasia revealed by parathyroid hormone determination in fine-needle aspirate, co-existing with multifocal papillary thyroid carcinoma

Anagnostis Panagiotis , Karras Spyridon , Adamidou Fotini , Christoforidou Varvara , Cox Jeremy

Introduction: Ectopic parathyroid tissue is a rare cause of primary hyperparathyroidism (PHPT). Intrathyroid location has been reported in 18–33% of cases.Case report: A 67-year-old Caucasian female was admitted for evaluation of multi-nodular goiter and normocalcaemic PHPT. The patient was asymptomatic; her medical history was remarkable for hypertension, dyslipidaemia, and albuminuria. Her family history has positive for albuminuria.<p class="...

ea0070ep449 | Thyroid | ECE2020

Esophageal perforation due to thyroid lymphoma

Anagnostis Panagiotis , Vaitsi Konstantina , Tzelepi Keraso , Kalaitzis Efstratios

Introduction: Primary thyroid lymphoma (PTL) represents about 1–5% of thyroid malignancies and < 2% of extra-nodal lymphoma. The most common subtype is diffuse large B-cell lymphoma (DLBCL) (~ 50% of cases), followed by mucosa-associated lymphoid tissue (MALT) lymphoma, both non-Hodgkin’ lymphomas. sophageal perforation is a very rare complication during the course of PTL, characterized by poor prognosis.Case presentation: A 65-year-...

ea0032p214 | Clinical case reports – Pituitary/Adrenal | ECE2013

An unusual case of Cowden-like syndrome, neck paraganglioma and pituitary adenoma

Efstathiadou Zoe , Anagnostis Panagiotis , Sapranidis Michalis , Kita Marina

Introduction: The description of a rare case of papillary thyroid cancer, neck paraganglioma, pituitary adenoma and Cowden-like syndrome.Case report: A 43-year-old woman presented with enlargement of her right thyroid lobe and a palpable ipsilateral neck mass. The pathology examination after operation of the two lesions revealed the synchronous presentation of a papillary thyroid carcinoma and a neck paraganglioma. Patient’s medical history included...

ea0032p247 | Clinical case reports – Pituitary/Adrenal | ECE2013

Occurrence of De Quervain’s thyroiditis after resolution of hypercortisolism following SOM230 treatment for Cushing’s disease and surgery for an adrenocortical adenoma: report of two cases

Efstathiadou Zoe , Sykja Albana , Anagnostis Panagiotis , Panagiotou Athanasios , Kita Marina

Introduction: Increased prevalence of thyroid autoimmunity has been described in few cases after successful treatment for Cushing’s syndrome. In De Quervain’s thyroiditis (DQT) autoimmunity does not seem to play a primary pathogenetic role.We describe two cases of DQT coinciding with the resolution of hypercortisolism, after successful treatment of Cushing’s syndrome/disease.Case 1: A 41-year-old female with Cushing&...