Endocrine Abstracts

Introduction: Thyroid ophthalmopathy occurs generally due to Graves’ disease. Only a few cases were reported about ophthalmopathy in the years following a thyroidectomy and RAI therapy or metastatic papillary thyroid cancer.Case: A forty-six-year-old female patient was operated on for the fine needle aspiration biopsy (FNAB) result of a suspicious follicular neoplasia. A pathology examination showed a papillary microcarcinoma and Hashimoto thyroidit...

Background: There is some evidence suggesting an interaction between renin-angiotensin-aldosterone system and parathyroid hormone (PTH). Decreased aldosterone levels after parathyroidectomy have been reported in patients with primary hyperparathyroidism (PHPT). Recently, most of the diagnosed patients with PHPT are mild or asymptomatic. Our aim was to investigate plasma aldosterone and renin concentrations in patients with asymptomatic PHPT.Methods: Thir...

Introduction: Werner syndrome (WS) is an autosomal recessive disease characterized by premature aging, skin changes, gray hair, alopecia, muscle atrophy, osteoporosis, and cataracts and has a high frequency of association with rare neoplasms. In addition, some endocrinological abnormalities were manifested in this rare disease, such as hypogonadism, diabetes mellitus, hyperlipidemia. Atrophic changes of organs and systems such as skin, brain and genital organs were reported. H...

Introduction: Hashimoto’s thyroiditis (HT) is common autoimmune thyroid disorder and is predominantly the clinical expression of cell-mediated immunity leading to destruction of thyroid cells. Vitamin D plays a role in the regulation of immunity and cell proliferation. So, do the serum levels of vitamin D reduced in HT?Methods: We examined the medical records of the ‘Thyroid policlinic’ patients with or without HT. Vitamin D, thyroid autoa...

Introduction: Thyroid lymphoma is a rare disease. Furthermore, coincidence of extrathyroidal lymphoma is very rare.Case: A 69 years-old woman patient was admitted to the hospital with dyspnea, hoarse voice and swelling of throat for a month. In her history, she had been diagnosed as gastric lymphoma 6 years ago, while she was being investigated for upper gastrointestinal bleeding. Six cures of chemotherapy has been applied. She was not on follow up. In p...

Aim: The present study was designed to examine the relationship between adiponectin gene (T45G in exon 2) polymorphism and clinical and hormonal characteristics in women with polycystic ovary syndrome (PCOS).Materials and methods: Ninety-six patients with PCOS and 93 healthy subjects were included in the study. Serum levels of sex steroids, insulin and adiponectin levels were measured. Insulin resistance was evaluated by homeostasis model assessment (HOM...

Idiopathic granulomatous hypophysitis is a very rare inflammatory disease of the pituitary gland. Primary hypophysitis represents a difficult diagnostic challenge because it can imitate pituitary adenomas clinically and radiologically. The diagnosis is usually made histologically by hypophysectomy. We herein present a rare case of idiopathic granulomatous hypopysitis diagnosed primarily by pituitary biopsy.Case: A 50-year-old female patient presented wit...

Objective: Serum total sialic acid(SA) concentration is assessed as an up to date risk indicator of atherosclerosis and cardiovascular diseases.Methods: It was aimed to investigate about how SA levels are effected in overt or subclinical hypothyroidism (SH) and how it’s associated with other atherosclerosis risk factors because there is no study about these topics, though SA is intensively studied in recent years.Patients: Six...

Also cytopenies can be established in the evaluation of Graves’ disease (GD), isolated thrombocytopenia is very rare. Here, we present a case of immune thrombocytopenia incidentally found in the evaluation of GD. A 48-year-old female was admitted to our hospital with palpitation and anxiousness. The thyroid function tests were concordant with thyrotoxicosis. She had two subcentimetre nodules in the right thyroid lobe. Thyroid gland had increased iodine uptake. And thyroid...

A 67–year-old female patient was transferred to our hospital from a nursing home for high capillary glucose levels and foot ulcer considered as diabetic foot infection. Her past medical history could not be obtained because of mental retardation with unknown etiology and absence of relatives.A purulent foot ulcer sized 4×3 cm was found in right heel. She also had deformities in her hands, feet, and her nose. Peripheral neuropathy was also detec...