Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1099 | Female Reproduction | ECE2017

Serum sclerostin and dickkopf-1 levels in polycystic ovary syndrome patients

Bilem Ogun , Bilem Yildiz , Eroglu Mustafa , Turkon Hakan , Akdeniz Yasemin Sefika , Asik Mehmet

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine pathology in premenopausal women and it is a complex syndrome affecting various systems. Numerous studies have been made about how the PCOS effects on bone metabolism, but currently there is no clear information. Wnt pathway plays important role in the regulation of bone metabolism. The sclerostin(Scl) and Dickkopf-1 (DKK1) inhibit this pathway and they has recently become a therapeutic target of osteo...

ea0032p308 | Clinical case reports - Thyroid / Others | ECE2013

Graves’ disease associated with severe hypoalbuminemi

Sen Hacer , Binnetoglu Emine , Asik Mehmet , Gunes Fahri , Akbal Erdem , Bozkurt Neslihan

Introduction: The most common cause of thyotoxicosis is Graves’ disease. Thyroid storm mostly presents with fever, tachycardia, arrthyhmia, jaundice, congestive heart failure and consciousness. We report a rare case of severe hypoalbuminemia with thyroid storm. To our knowledge it is the first case of severe hypoalbunemia due to thyrotoxicosis in literature.Case: Forty one years old female had been followed up with the diagnosis of Graves’ dise...

ea0016p684 | Thyroid | ECE2008

Anti-BIP levels on Hashimoto's thyroiditis

Asik Mehmet , Sahin Mustafa , Arikan Serap , Gursoy Alptekin , Ayturk Semra , Bakiner Okan , Tutuncu Neslihan Bascil

To asses the presence of antibodies to BIP/GRP78, which is a chaperon of endoplasmic reticulum and has immune modulating and antiapoptotic effects in Hashimoto’s thyroiditis.The study included 62 patients with autoimmune thyroiditis. Of these, 20 had euthyroid, 27 had subclinical hypothyroid, and 15 had hypothyroid Hashimato’s thyroiditis. A control group including 37 healthy patients also participated in the study.There ...

ea0035p5 | Adrenal cortex | ECE2014

Are small adrenal incidentalomas solely a radiological finding?

Asik Mehmet , Eroglu Mustafa , Turkon Hakan , Binnetoglu Emine , Gunes Fahri , Sen Hacer , Erbag Gokhan , Yilmaz Yeliz , Sahin Mustafa , Ukinc Kubilay

Introduction: The criteria defining the threshold size of adrenal incidentaloma (AI) are >1 cm diameter. However, data about AI ≤1 cm diameter is scant. The aim of this study is to evaluate function of adrenal masses ≤1 cm and to compare them with adrenal masses >1 cm as well as to understand the possible utility of determining salivary cortisol in diagnosis of SCS in patients with AI.Method: The study included 137 consecutive patient...

ea0035p620 | Female reproduction | ECE2014

Plasma levels of nesfatin-1 in patients with polycystic ovary syndrome

Binnetoglu Emine , Erbag Gokhan , Gencer Meryem , Turkon Hakan , Asik Mehmet , Gunes Fahri , Sen Hacer , Vural Ahmet , Ukinc Kubilay

Introduction: Polycycstic ovary syndrome (PCOS) is an important disorder in women of reproductive age which is characterised with menstrual dysfunction, anovulation and hyperandrogenism. 5–10% of the female population affected by this syndrome. Nesfatin-1 is a new anorexigenic hormone which is expressed from several regions of hypothalamus and peripheral tissues. Nesfatin-1 is related with obesity, insulin resistance and appetite. We aimed to evaluated the nesfatin-1 leve...

ea0032p259 | Clinical case reports – Pituitary/Adrenal | ECE2013

Gastrointestinal bleeding associated with Dabigatran in a patient with panhypopituitarism

Gunes Fahri , Asik Mehmet , Sen Hacer , Binnetoglu Emine , Akbal Erdem , Bilen Ogun Irem , Ukinc Kubilay , Adam Gurhan

Introduction: Dabigatran is a direct thrombin inhibitor which is used for reducing the risk of stroke or systemic embolism in patients with atrial fibrillation. Although INR monitoring is not required in the course of treatment, it may be complicated with spontaneous systemic bleeding. Sheehan’s syndrome is characterized with panhypopituitarism which is caused by necrosis of the pituitary gland. Recent studies have demonstrated that panhypopituitarism is associated with b...

ea0032p309 | Clinical case reports - Thyroid / Others | ECE2013

Graves’ disease associated with Alopecia areata developed after Hashimoto's thyroiditis

Asik Mehmet , Binnetoglu Emine , Sen Hacer , Gunes Fahri , Akbal Erdem , Tekeli Zeliha , Oguz Sevilay , Uysal Fatma , Ukinc Kubilay

Indroduction: Graves’ and Hashimoto’s thyroiditis are the most common autoimmune thyroid diseases. After Graves’, hypothyroidism can develop spontaneously or as a result of medical treatment, radioactive iodine therapy or surgery. Development of Graves’ after Hashimoto’s thyroiditis is a rare condition. Alopecia areata (AA) is an autoimmune disease. It has association with other autoimmune diseases such as thyroid disorders, anemias and other skin diso...

ea0035p968 | Thyroid (non-cancer) | ECE2014

Evaluation of epicardial adipose tissue thickness in patients with overt hyperthyroidism

Binnetoglu Emine , Asik Mehmet , Altun Burak , Gunes Fahri , Sen Hacer , Gazi Emine , Erbag Gokhan , Bilen Yildiz Garip , Akbal Erdem , Temiz Ahmet , Barutcu Ahmet , Bekler Adem , Ukinc Kubilay

Objective: Thyroid diseases are among the most common endocrine disease and with a prevalence of 1.2%. Thyroid hormones have several effects on cardiovascular system. Many studies showed the association between hyperthyroidism and acute ischemic heart disease with conflicting results. Epicardial adipose tissue (EAT) thickness is a marker of atherosclerosis and independent predictor of coronary artery disease. In this study, we aimed to evaluate the EAT thickness in patients wi...