Endocrine Abstracts

Introduction: Prolactinoma is the most common form of all pituitary tumors, and currently, treatment with cabergoline constitutes first choice therapy for prolactinoma. Surgical approach is recommended when medical therapy fails or visual disturbance due to pituitary mass develops. Here we present a case of macroprolactinoma who developed empty sella and optic chiasm protrusion secondary to cabergoline treatment.Case: A 20-year-old male patient referred ...

Introduction: Hypopituitarism is characterized by decreasing of pituitary hormones, which can result from diseases of the pituitary gland or the hypothalamus. The prevalence of hypopituitarism is 30–45 out of 100 000 in the world wide. Causes of panhypopituitarism are non-tumoral hypotalomopituitary reasons (50%), pituitary tumors (43%) and extra-pituitary tumors (7%). Here we want to present a very rare case of pan hypopituitarism; pituitary stalk interruption syndrome (...

Introduction: Cushing’s disease (CD) is rare systemic disease characterized by an endogenous hypercortisolism and it is the most common cause of Cushing’s syndrome (CS). CS is encountered more often in women than in men, associated with an increased morbidity and mortality. Hence, early diagnosis and proper management of the condition is crucial. Here, we present a case of CD, who had abdominoplasty and reduction mammoplasty but went undiagnosed long time with correc...

Introduction: Despite the fact that Graves’ disease (GD) almost always presents as a diffuse hyperfunctioning goiter involving both lobes of the thyroid gland, it may rarely reveal at only unilateral lobe with bilobar thyroid gland. We herein present a case of unilateral GD involving the right thyroid lobe of a bilobar gland.Case report: A 42-year-old woman presented with symptoms and signs of hyperthyroidism; thyrotropin (TSH) was undetectable, whi...

AimsDuring April and May 2020 in Turkey, changing priorities in the health system and some restrictions on daily life in order to prevent the spread of SARS-CoV-2 infection may worsen metabolic control of people with diabetes. We aimed to investigate whether glycemic dysregulation or disturbance of lipid metabolism occur in people with diabetes during the lockdown period.MethodsThis retrospective study includ...

ObjectivesMale prolactinoma patients mostly have hypogonadotropic symptoms. While treatment with dopamine agonists (DAs; such as bromocriptine or cabergoline) leads to recovery of sexual glands, it can lead to impulsive control disorders as an undesirable side effect. The aim of this retrospective study is to determine the level of testosterone that eliminates symptoms, provides fertility and does not cause this undesirable side effect regardless of prol...

Multiple endocrine neoplasia type 1 is a rare autosomal-dominant disorder. The most common endocrine tumors are parathyroid tumors, which cause hyperparathyroidism and hypercalcemia. Other tumors of MEN 1 include pituitary tumors for example prolactinomas and enteropancreatic tumors such as gastrinomas, insulinomas, VIPomas, carcinoid tumors. We report a case of a 31 year old male with MEN 1 presenting hypercalcemia with complaints of fatigue and weakness. On further questioni...

Objective: Graves’ disease (GD) occurs as a result of genetic and environmental factors that trigger autoimmunity. Some pro-inflammatory cytokines have already been linked to an increased susceptibility of developing GD. Recently, it has been reported that Covid-19 infection and SARS-CoV-2 vaccination trigger the emergence of new GD cases or disease recurrence as environmental factors due to the pandemic. However, there is no data in the literature reporting the effects o...

Aim: İmpaired glucose tolerance and hyperinsulinism/insulin resistance frequently accompany by acromegaly. NLO (Neutrophile lymphocyte ratio) is demonstrated as a simple indicator of systemic inflammation and it is also known that NLO is associated with atherosclerosis progression in coronary artery and a risk factor in coroner artery disease. In this study, we intend to search the association between both coronary atherosclerosis seen frequently in patients diagnosed wi...

BackgroundMedullary thyroid carcinoma (MTC) accounts for 3–5% of thyroid cancers, but recurrent MTC, manifested by elevated calcitonin levels, is a common problem. We aimed to perform a calcitonin washout procedure simultaneously with cytological evaluation and compare their effectiveness to diagnose metastatic lymph nodes.Methods94 patients diagnosed with MTC were recruited from our institutional datab...