Searchable abstracts of presentations at key conferences in endocrinology

ea0056p354 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Increase in C-peptide levels after short term glycemic control in patients with type 2 diabetes mellitus: myths or facts?

Topaloglu Omercan , Evren Bahri , Sahin Ibrahim

Introduction: Long term control of glucotoxicity has been shown to increase the secretion of insulin and C-peptide (Cp) from beta cells. However, there is limited data concerning the effect of short term glycemic control and reversal of glucotoxicity on basal Cp. We aimed to investigate the change in serum Cp levels after short term glycemic control in patients with uncontrolled type 2 diabetes mellitus (DM).Materials and methods: A total of 123 patients...

ea0049ep330 | Clinical case reports - Thyroid/Others | ECE2017

A case of intrathyroidal parathyroid adenoma presented with severe 25(OH)D3 deficiency, bone pain and high PTH

Topaloglu Omercan , Evren Bahri , Sahin Ibrahim , Unal Bulent

The most frequent pathology of primary hyperparathyroidism presented with the findings of hypercalcemia is parathyroid adenoma. Some patients having the signs of primary hyperparathyroidism may have intrathyroidal parathyroid adenoma and it may be overlooked. We present a case of intrathyroidal parathyroid adenoma presented with bone pain.47-year-old female patient referred to our clinics with bone pain and she had no pruritus, dry mouth, dyspepsia, abdo...

ea0049ep620 | Diabetes therapy | ECE2017

Palpable purpura in an uncontrolled diabetic patient: an uncommon possible side effect of linagliptin

Topaloglu Omercan , Evren Bahri , Kara Mahmut , Yucel Seyfullah , Sahin Ibrahim

Introduction: Incretin based therapeutics have commonly been used in the last years for the management of patients with type 2 diabetes mellitus (DM). Linagliptin is a member of “dipeptidyl peptidase 4” (DPP-4) inhibitors and often preferred owing to some advantages over the others. We present a diabetic case developing skin findings after the initiation of linagliptin.Case: 66 year-old woman with a history of type 2 DM for 10 years was admitte...

ea0049ep703 | Obesity | ECE2017

Are there any associations between vitamin D levels and insulin resistance in obese patients?

Topaloglu Omercan , Evren Bahri , Yologlu Saim , Sahin Ibrahim

Introduction: Most of the human studies suggested an association between obesity and low 25(OH)D3 0levels. It has been proposed that co-existence of vitamin D deficiency may have a role in the development of IR in obesity. We aimed to reveal whether any association was present between IR and 25(OH)D3.Materials-methods: 223 obese patients referred to our clinics were evaluated for the study. 24 patients with known diabetes mellitus were excluded. Finally,...

ea0035p1106 | Thyroid Cancer | ECE2014

The role of DNA repair proteins in the assessment of thyroid nodules

Evren Bahri , Karadag Nese , Yilmaz Sami , Sertkaya Ayse Cikim

Aims: Bening and malignant thyroid nodules are the most common lesions of endocrine glands. Some molecular markers; Mut-S homolog-2 (MSH2) and Mut-L-homolog-1 (MLH1) are the two of DNA repair proteins and metil guanin–DNA-metil transferase (MGMT) is the DNA repair enzymes have been studied. In this study, our aim is to evaluate MSH2, MLH1, and MGMT levels in papillary thyroid cancer (PTC), multinodular colloidal goitre (MNG), and chronic lymphocytic thyroiditis (CLT) and ...

ea0090p632 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Changing clinical features of diabetic ketoacidosis: any impact of SGLT2 inhibıtors is there?

Genc Selin , Evren Bahri , Selcuk Yiğit Onur , Şahin İbrahim

Aims: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) increase the risk for diabetic ketoacidosis, particularly in patients with type 1 diabetes (T1DM). We aimed to determine whether SGLT2i use increase the risk of euglycemic diabetic ketoacidosis (euDKA) and to indicate its demographic, clinical features.Methods: We performed a retrospective cohort study of 51 patients over 18 years-old admitted to emergency unit at a tertiary care hospital from 2018...

ea0056p483 | Diabetes therapy | ECE2018

Maculopapular rash developed after initiation of U-300 glargine insulin in a patient with type 1 diabetes mellitus

Topaloglu Omecan , Evren Bahri , Bilgic Mehmet Akif , Kara Mahmut , Sahin Ibrahim

Introduction: U-300 insulin glargine has been used as a concentrated form of glargine. Skin and subcutaneous tissue disorders (eg, rash, pruritus, and urticaria) have been reported with insulin glargine. But to our knowledge, maculopapular rash has not been reported with use of U-300 insulin glargine. We present a patient with type 1 diabetes mellitus(DM) developing maculopapular rash after initiation of U-300 glargine insulin.Case Report: 37 year-old fe...

ea0070aep306 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

New-onset diabetes mellitus after liver transplantation in the patients with acute liver failure: Is there any effect of pretransplant hypoglycemia?

Topaloğlu Ömercan , Cengiz Muhammet , Cengiz Ayșe , Evren Bahri , Yoloğlu Saim , Yılmaz Sezai , Şahin İbrahim

Introduction: The frequency of new-onset diabetes after transplant (NODAT) is 5–30% in liver transplant recipients. We aimed to analyze the frequency and predictors of NODAT in the patients undergoing liver transplantation (LTx) due to acute liver failure(ALF), and to investigate whether pretransplant hypoglycemia had any effect on NODAT.Materials and methods: Adult patients undergoing LTx due to ALF were analyzed retrospectively. The patients with...

ea0070ep377 | Reproductive and Developmental Endocrinology | ECE2020

Is there relationship between serum Igf-1 and thyroid nodule, thyroid or ovarian volume in polycystic ovarian syndrome?

Topaloğlu Ömercan , Evren Bahri , Uzun Mehmet , Yoloğlu Saim , Güldoğan Emek , Şahin İbrahim

Introduction: Studies investigating the association between serum IGF-1, and thyroid nodule, ovarian or thyroid volume in polycystic ovarian syndrome (PCOS) are limited. We aimed to analyze the association between serum IGF-1 level, and ovarian or thyroid volume, or thyroid nodule in PCOS.Materials and methods: The study was performed between June 2017 and August 2019 as prospective design. The patients referred to our medical faculty were included. Adul...

ea0090ep259 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

COVID-19 infection in lipodystrophy syndromes

Semiz Gokcen Gungor , Demir Tevfik , Simsir Ilgin Yildirim , Selimoğlu İsmail , Yılmaz Muge , Unal Mehmet Cağrı , Ellidıkuz Hulya , Onay Huseyin , Gen Ramazan , Evren Bahri

Purpose: The coronavirus disease 2019 (COVID-19) has a high morbidity and mortality in patients with chronic disorders. This study was aimed at assessing the frequency and outcomes of COVID-19 in patients with lipodystrophy syndrome and investigating the effect of restricted access to the hospital during pandemic on metabolic parameters.Methods: A survey comprising descriptive questions about the situation of the patients during the COVID-19 pandemic was...