Endocrine Abstracts

Grave’s disease (GD), like all autoimmune diseases, is predominantly female, with sex ratio to 3 women for one man. The treatment of first intension is based on antithyroid drugs (ATD). Our objective is to compare the clinical presentation and the evolution of GD by gender. It’s a retrospective study. We studied patients with a first diagnosis of GD, in the department of endocrinology in Farhat Hached hospital in Susah, between Juanuary 2010 and December 2015. The pa...

IntroductionThe association between parathyroid and thyroid diseases is not uncommon; however concurrent presence of parathyroid adenoma and thyroid cancer is rare (1). As a natural consequence, preoperative imaging studies for diagnosis and localization of parathyroid adenomas may result with the detection of thyroid incidentalomas and most of these thyroid nodules should be evaluated by fine-needle aspiration biopsy before parathyroid surgery (1). We h...

Introduction: Monogenic diabetes is a rare type of diabetes that should be evoked in the presence of associated features. Here we report a female patient with complete phenotype of MODY5 while discussing its possible complications.Case report: A.B was 35-year-old patient with a rich family history of diabetes and renal cysts. Sha had a personal medical history of Diabetes since the age of 23 years, on basal bolus insulin regimen, recurrent episodes of ur...

Introduction: Hypoparathyroidism (HypoPT) is a rare endocrine disease characterized by abnormally low concentrations of PTH resulting in hypocalcemia. Etiologies are various and are dominated by postoperative HypoPT. HypoPT needs a lifelong treatment and follow-up in order to maintain appropriate calcium levels and prevent chronic complications.Patients and Methods: A retrospective descriptive study was conducted at the endocrinology department in Fattou...

Introduction : Primary adrenal lymphomas (PAL) are extremely rare and constitute 0.5% of all adrenal tumors. The number of cases described is approximately 70 cases [1] and It is bilaterally manifested in approximately 70% of cases [2]. The diagnosis is made on histological features, as there is no specific symptoms. Treatement is based on chemotherapy and prognosis is usually poor. We report two cases of bilateral PAL.Cases: First case: A 63-year-old wo...

Introduction: Cushing’s disease (CD) is associated with metabolic and cardiovascular comorbidities that can be incompletely resolved after disease remission. Our objective was to evaluate the metabolic and cardiovascular status of patients with MC in remissionPatients and methods: We performed a retrospective study including 15 CD patients cured by pituitary surgery. Patient’s medical records were reviewed and information regarding blood pressu...

IntroductionBilateral adrenal incidentalomas represent about 15% of adrenal incidentalomas. Their investigation and management are less discussed and more challenging than unilateral incidentalome. A special attention is required because they are more likely to be pathologic. When associated with a synchronous extra-adrenal tumor, the first diagnosis is adrenal metastasis, but this is not always true. Here we present a rare association of pheochromocytom...

IntroductionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that caused a global pandemic in 2020. The virus has infected more than 100 million people worldwide and the pandemic is still spreading. It can affect practically all organs. Data on the impact of SARSCoV-2 on the thyroid gland are very scarce. Two patients with Graves’ disease (GD) and COVID-19 have been recently published(1). We present a case GD occur...

Introduction: Adrenocortical carcinoma is a very rare tumor with a heterogenous prognosis.Case report: Patient R.B is a 58-year-old female patient with no particular familial history. She had a personal history of hypertension, discovered 6 months ago well controlled with beta blockers and amlodipine. Two weeks before her admission to the hospital, she reported having constantly worsening abdominal pain followed by frequent vomiting few days later. The p...

Introduction: Pheochromocytoma is a rare tumour of the adrenal medulla. The aim of our work is to describe the clinical, biological and anatomopathological profile of pheochromocytomas.Material and method: Retrospective descriptive study carried out in the endocrinology department of the Fattouma Bourguiba University Hospital, Monastir, Tunisia.Results: Analysis of a series of 13 cases found 9 women and 4 men with an average age of...