Searchable abstracts of presentations at key conferences in endocrinology

ea0035p1008 | Thyroid (non-cancer) | ECE2014

Recurrence of Graves' disease after radioiodine treatment: factors related to treatment failure

Moreno Carolina , Pires Luis , Cardoso Luis , Ruas Luisa , Saraiva Joana , Guelho Daniela , Vicente Nuno , Costa Gracinda , Carrilho Francisco

Introduction: Radioiodine (RAI) therapy is an inexpensive and reliable therapeutic option for Graves’ disease (GD). However, individual characteristics of the disease can influence therapeutic success. The identification of these factors may help to predict outcome and select optimal pre-treatment conditions.Aim: To assess clinical, laboratory and radioactive parameters that may lead to RAI treatment failure in patients with GD....

ea0035p1111 | Thyroid Cancer | ECE2014

Prognostic implications of stage pT3 in well differentiated thyroid cancer

Moreno Carolina , Melo Miguel , Pires Luis , Cardoso Luis , Ribeiro Cristina , Ruas Luisa , Saraiva Joana , Guelho Daniela , Vicente Nuno , Costa Gracinda , Carrilho Francisco

Introduction: The TNM staging system for well differentiated thyroid cancer (WDTC) considers tumours over 4 cm diameter limited to the thyroid or tumours with minimal extra-thyroid extension to be classified as pT3. This stage can be considered quite heterogeneous, as different clinical and pathologic characteristics seem to have distinct prognosis value.Aims: To determine prognostic factors amongst clinical, laboratorial, histologic and radiologic chara...

ea0037gp.22.03 | Pituitary–Therapy of Cushing's disease | ECE2015

Impact of preoperative magnetic resonance in surgical care of patients with Cushing's disease

Guelho Daniela , Martins Diana , Paiva Isabel , Cardoso Luis , Vicente Nuno , Oliveira Diana , Balsa Margarida , Carrilho Francisco

Introduction: Cushing’s disease (CD) is a rare disorder caused by an ACTH-secreting pituitary adenoma. Transsphenoidal surgery (TSS) is the recommended first-line treatment. However, an equivocal or even normal preoperative MRI can preclude the surgical management and the outcome of these patients.Objectives: Evaluate the relationship between preoperative MRI and TSS efficacy in patients with CD.Methods: Retrospective cohort s...

ea0037ep512 | Diabetes (complications & therapy) | ECE2015

Continuous subcutaneous insulin infusion decreases hypoglycaemia during nighttime

Vicente Nuno , Cardoso Luis , Baptista Carla , Barros Luisa , Guelho Daniela , Oliveira Diana , Martins Diana , Carrilho Francisco

Introduction: Continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI) are forms of intensified insulin therapy and the most used regimens for type 1 diabetes (T1D). Owing to its continuous basal output, hypoglycaemic events tend to be rarer with CSII. Our goal was to evaluate the differences in nocturnal hypoglycemia between these two treatment strategies.Methods: Retrospective analysis of 61 patients who had performed continu...

ea0035p328 | Clinical case reports Thyroid/Others | ECE2014

Gynecomastia: a rare etiology

Vicente Nuno , Barros Luisa , Saraiva Joana , Moreno Carolina , Guelho Daniela , Cardoso Luis , Carrilho Francisco

Introduction: Gynecomastia is a frequent reason for endocrinology consultation and its correct investigation is pivotal towards a precise diagnosis. We present a clinical case of a rare cause of gynecomastia.Case report: A 56-year-old male was referred to the hospital setting for an endocrinology consultation. He noticed increased breast size for a year, initially tender to palpation, and unquantified weight loss. Neither galactorrhea, nor any nipple dis...

ea0035p609 | Endocrine tumours and neoplasia | ECE2014

Adrenocortical carcinomas: retrospective analysis of the last 22 years

Guelho Daniela , Paiva Isabel , Vieira Alexandra , Saraiva Joana , Moreno Carolina , Vicente Nuno , Cardoso Luis , Carrilho Francisco

Introduction: Adrenocortical carcinoma (ACC) is a rare disease, with a severely adverse prognosis. Clinical reports, even when including a limited number of cases, can contribute to its knowledge. This study aims to characterize patients followed at our department between 1991 and 2013.Methods: Retrospective analysis of the clinical records of patients with pathological confirmation of ACC. Statistical analysis: SPSS21.Results: 22 ...

ea0035p944 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Weight and metabolic profile evolution in patients with treated prolatinomas

Guelho Daniela , Gomes Leonor , Paiva Isabel , Saraiva Joana , Moreno Carolina , Cardoso Luis , Vicente Nuno , Carrilho Francisco

Introduction: The metabolic consequences of hyperprolactinemia and the repercussions of its treatment with dopaminergic agonists are not yet fully understood. This study aims to evaluate the metabolic profile of patients with prolactinomas (prevalence of diabetes mellitus, dyslipidaemia and obesity) and identify the potential variations after treatment with bromocriptine.Methods: Retrospective study of patients followed between 1962 and 2013. Included 17...

ea0041ep75 | Adrenal cortex (to include Cushing's) | ECE2016

Massive bilateral pheocromocytomas – a rare case

Martins Diana , Rodrigues Dircea , Baptista Carla , Melo Miguel , Cardoso Luis , Vicente Nuno , Oliveira Diana , Ventura Mara , Lages Adriana , Carrilho Francisco

Introduction: Pheochromocytoma is a rare catecholamine-secreting tumor that arises from the chromaffin tissue of the adrenal medulla. Of the reported cases, only 10% consist in bilateral lesions and the probability of multiple endocrine neoplasia should always be investigated.Case report: Female patient, 19 years old, presented with a clinical history with 2 years of evolution, characterized by episodes of palpitations, headache and abdominal discomfort....

ea0041ep115 | Bone &amp; Osteoporosis | ECE2016

The effect of anorexia nervosa on bone

Vicente Nuno , Rodrigues Dircea , Barros Luisa , Guelho Daniela , Cardoso Luis , Oliveira Diana , Martins Diana , Ventura Mara , Lages Adriana , Carrilho Francisco

Introduction: One of the most common endocrine complications of anorexia nervosa (AN) is the decrease in bone mineral density. The authors evaluated the predictive factors of osteopenia and osteoporosis in AN patients admitted with low weight.Patients and methods: Retrospective analysis of 45 patients admitted with AN between 2001 and 2015 in the Endocrinology department, corresponding to 63 admissions. Bone mineral density was classified according to WH...

ea0041ep279 | Clinical case reports - Pituitary/Adrenal | ECE2016

Addison disease in antiphospholipid syndrome – case report

Oliveira Diana , Paiva Sandra , Rodrigues Marcia , Guelho Daniela , Cardoso Luis , Vicente Nuno , Martins Diana , Lages Adriana , Ventura Mara , Carrilho Francisco

Introduction: Primary adrenal insufficiency or Addison disease (AD) is a potentially fatal condition if not diagnosed in time. Rarely, it can arise as a manifestation of antiphospholipid syndrome (APS), caused by adrenal venous thrombosis and consequent hemorrhagic infarction.Case report: We present the case of a 36-year-old caucasian woman with APS diagnosis since she was 24, with history of arterial hypertension and multiple thrombotic events (deep vei...