Searchable abstracts of presentations at key conferences in endocrinology

ea0090p204 | Reproductive and Developmental Endocrinology | ECE2023

Searching For The Testicles: A Medical Mystery?

Maria Dumitrache Sabina , Stan Raluca , Grosu Iustina , Zubaci Ana , Iliescu Marina , Tarna Mihaela , Mirica Alexandra , Nicoleta Cima Luminita , Cima Luminita

Introduction: Cryptorchidism is unilateral or bilateral absence of the testes from the scrotum. One of the differential diagnosis is congenital bilateral anorchia. Vanishing testes syndrome is associated with low serum AMH concentrations and an absent or subnormal response to stimulation with hCG. We report the case of a 22-year-old boy diagnosted with bilateral cryptorchidism and hypergonadotropic hypogonadism at the age of 17 years old. At the time of diagnosis the scrotum w...

ea0049ep262 | Calcium & Vitamin D metabolism | ECE2017

Long standing primary hyperparathyroidism consequences after parathyroid surgery: fast recovery not only for bone mass

Stefan Cristina , Arhire Amalia , Cima Luminita , Barbu Carmen

Background: Primary hyperparathyroidism is usually a long evolving disease before the diagnosis, thus patients who are not diagnosed by routine screening tests may have a lot of complications affecting the bone, kidney, bone marrow.Aim: Pointing out the possibility of fast recovery not only for bone mass.Material: We present a case of primary hyperparathyroidism, a female patient 66 years old, sent to emergency room, dehydrated, as...

ea0037ep123 | Steroids, development and paediatric endocrinology | ECE2015

Is there a link between lipid profile and thyroid function modification during somatropinum treatment for GH deficiency in children?

Stejereanu Lavinia , Cima Luminita , Albu Alice , Barbu Carmen , Fica Simona

Background: Previous studies suggested that treatment with somatropinum in children with GH deficiency (GHD) may alter lipid profile and pituitary–thyroid axis function. However, results are divergent and data regarding a possible association between changes of thyroid function and of circulating lipids are scarce. The aim of this study was to report the changes of the lipid profile in children with GHD treated with somatropinum and the relationship between thyroid functi...

ea0077p34 | Bone and Calcium | SFEBES2021

Vitamin D deficiency and inflammation in IBD patients

Soare Iulia , Sirbu Anca , Diculescu Mircea , Mateescu Bogdan Radu , Tieranu Cristian , Cima Luminita , Fica Simona

Introduction: Vitamin D is a potential immune modulator and low levels are common in inflammatory bowel disease (IBD) patients. The aim of the study was to determine the association between deficient vitamin D and inflammatory profile.Methods: Intestinal (fecal calprotectin) and blood inflammatory profile [erythrocytes sedimentation rate (ESR), protein C reactive, fibrinogen], were performed to all patients. In addition, level of 25 hydroxy vitamin D was...

ea0081ep127 | Adrenal and Cardiovascular Endocrinology | ECE2022

A newly diagnosed Cushing’s syndrome after a visit at the Emergency Department

Iliescu Marina , Tarna Mihaela , Andrei Marian , Cima Luminita Nicoleta , Martin Carmen Sorina , Simona Fica

Cushing’s syndrome results from an excess exposure to glucocorticoids which can result from various causes, divided into ACTH-dependent and ACTH-independent etiologies. An example of ACTH-independent causes are adrenal masses which are either benign adenomas, representing the majority of adrenal mass cases, or by malignant neoplasms. We present the case of a 52 yo woman who presented at the Emergency Department (ER) with thoracic pain and palpitations, for which several c...

ea0081ep719 | Pituitary and Neuroendocrinology | ECE2022

FSH- secreting pituitary microadenoma and ovarian hyperstimulation

Andrei Marian , Cima Luminita Nicoleta , Tarna Mihaela , Iliescu Marina , Simona Fica

Introduction: The prevalence of functioning gonadotropinoma is difficult to assess since most of reports are case reports. Gonadotropinomas rarely lead to a noticeable clinical syndrome. They usually produce symptoms associated with mass effect such as headaches, visual field impairment and hormonal deficiencies.Case report: We present the case of a 38 years old women diagnosed in 2017 with microprolactinoma. She had elevated prolactin level (108 ng/ml) ...

ea0090ep637 | Endocrine-related Cancer | ECE2023

Neuroendocrine carcinoma of the vagina in a young patient – a rare entity

Duta Simona Gabriela , Dumitras Teodor , Sorina Martin Carmen , Cima Luminita , Nitipir Cornelia , Terzea Dana , Fica Simona

Primary vaginal malignancy is uncommon, accounting for about 2% of all gynecological tract cancers, with small-cell neuroendocrine carcinoma of the vagina being exceptionally rare and aggressive. They display similar histological and immunohistochemical features to small-cell carcinomas of different origin. Few cases are reported in the literature so far and therefore, there is no current treatment protocol consensus. We report the case of a 34-year-old nulliparous patient, wh...

ea0090ep813 | Pituitary and Neuroendocrinology | ECE2023

Craniopharyngioma masquerading as a suprasellar Rathke cleft cyst in a young patient with a history of Ewing sarcoma: A case report

Ioana Ruxandra Calapod , Cima Luminita , Mirica Alexandra , Ulpia Comsa Codruta , Dragomir Monica , Stoica Sergiu , Fica Simona

Craniopharyngiomas are rare, benign tumors, typically found in childhood or early adulthood, that can cause a wide range of symptoms such as visual impairment, headaches, nausea and endocrine disturbances. Ewing sarcoma, on the other hand, is a rare and aggressive tumor that arise from primitive neuroectodermal cells and represents about 10% of all pediatric osseous primary tumors. We present the case of a 14-year-old patient who was admitted to our clinic in March 2022 for ob...

ea0063p478 | Calcium and Bone 2 | ECE2019

Trabecular bone score - a more sensible indicator in predicting negative change than bone mass density?

Soare Iulia Simona , Sirbu Anca Elena , Mateescu Bogdan Radu , Cima Luminita Nicoleta , Fica Simona

Background: Glucocorticoid-induced osteoporosis is common in chronic diseases as inflammatory bowel disease. Although BMD (bone mass density) is used for the estimation of the quantity of the bone, on the contrary, TBS (trabecular bone score) is a new parameter, a gray-level textural assessment of bone microarchitecture, providing estimation of quality of bone. Several studies showed increased level of TBS during teriparatide treatment in glucocorticoid induced osteoporosis.</...

ea0049ep763 | Clinical case reports - Thyroid/Others | ECE2017

Endocrine complications in a female patient with β-thalassemia major following bone marrow transplantation

Cima Luminita Nicoleta , Lambrescu Ioana Maria , Stejereanu Lavinia , Colita Anca , Fica Simona

We report the case of a 14-year-old female patient with β-thalassemia major (β-TM) that presented numerous endocrine complications following bone marrow transplantion (BMT). The patient was admitted in our department for endocrine evaluation 3 years after BMT. She was diagnosed with β-TM at 1 year of age and received chronic blood transfusions and oral chelating therapy until 2012 when BMT was performed. The patient developed acute skin and intestine graft-versu...