Searchable abstracts of presentations at key conferences in endocrinology

ea0063p908 | Diabetes, Obesity and Metabolism 3 | ECE2019

Association of dipeptidyl peptidase 4 inhibitor use with risk of bullous pemphighoid

Damas-Fuentes Miguel , Gomez-Perez Ana , Munoz-Garach Araceli , Mancha-Doblas Isabel , Tinahones-Madueno Francisco

Introduction: Recent studies suggest that the use of dipeptidyl peptidase 4 inhibitors (DPP-4i) may be associated with an increased risk of developing bullous pemphigoid; which has led to publication of several pharmacovigilance alerts.Objectives: To characterize the potential association between the use of DPP-4i and the risk of developing bullous pemphigoid.Material & methods: Observational, retrospective study based on clini...

ea0081p454 | Reproductive and Developmental Endocrinology | ECE2022

Different grade of obesity influences the association between 25-hydroxyvitamin and Testosterone levels: A cross-sectional study in young Spanish men with Obesity

Boughanem Hatim , Damas-Fuentes Miguel , Vega Maria Molina , Jose Tinahones Madueno Francisco , Carlos Fernandez Garcia Jose , Macias Manuel

Backgrounds: One of the most observations in subjects with obesity, is a high prevalence of vitamin D deficiency, which, in turn, it has been implicated with decreased testosterone levels and an increased hypogonadism risk. Testosterone deficiency is a very common feature in males with obesity. However, only few studies have investigated the effect of vitamin D on testosterone in the context of obesity, and controversial results has been found.Hypothesis...

ea0081ep315 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Analysis of glycemic control in type 1 diabetes patients using flash glucose monitoring

Damas-Fuentes Miguel , Martinez Montoro Jose Ignacio , Simon Frapolli Victor , Fernadez Valero Andrea , Tinahones Madueno Francisco Jose

Introduction: Flash glucose monitoring expansion to an increasing number of patients with type 1 diabetes, coupled with its increased accuracy and ease of use, has increased available data on glycemic control in this population and allows detection of improvement areas in diabetes education and treatment.Objective: To analyze main parameters standardized by ATTD consensus (2019) in our population of patients with type 1 diabetes using flash glucose monit...

ea0056p362 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Is it useful the O’Sullivan test ≥200 to diagnose gestational diabetes mellitus (GDM)?

Molina-Vega Maria , Picon-Cesar Maria Jose , Hernandez-Garcia Carmen , Damas-Fuentes Miguel , Diaz-Perdigones Cristina , Tinahones-Madueno Francisco

Introduction: A two-step approach is usually used to diagnose GDM. At 24–28 weeks of pregnancy, a 50 g 1-hour glucose or O’Sullivan test is performed. If it is positive (≥140 mg/dl), it is followed by a 100 g-3 hours-Oral Glucose Tolerance Test (OGTT) which is considered positive if at least two or more values are ≥ of reference values (105-190-165-145 mg/dl). Despite it is not include in any clinical practice guideline, sometimes the 100 g OGTT is obviat...

ea0063p42 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Endocrine hypertension?

Maraver-Selfa Silvia , Damas-Fuentes Miguel , Cornejo-Pareja Isabel Maria , Molina-Vega Maria , Munoz-Garach Araceli , Hernandez-Garcia Carmen , Mancha-Doblas Isabel , Tinahones Francisco

An 18-years-old woman without medical history was referred for study of hypertension and an adrenal incidentaloma. The family history was significant for essential well-controlled hypertension in her father; diagnosed at 39 years-old. The patient complained of headache, asthenia, edema in lower limbs, high blood pressure values (200/150 mmHg) for one year (well controlled with losartan 100 mg/12 h, amlodipine 10 mg/24 h and doxazosin 4 mg/24 h) and marked facial acne previous ...

ea0063p105 | Calcium and Bone 1 | ECE2019

Parathyroid carcinoma: identity with diagnostic difficulties and therapeutic strategies

Maria Diaz Perdigones Cristina , Maria Gomez Perez Ana , Maria Cornejo Pareja Isabel , Munoz Garach Araceli , Damas Fuentes Miguel , Molina Vega Maria , Maraver Selfa Silvia

Blackground: Parathyroid carcinoma is a malignant neoplasm affecting 0.5 to 5.0% of all patients suffering from primary hyperparathyroidism. This cancer continues to cause challenges for diagnosis and treatment because of its rarity, overlapping features with benign parathyroid disease.Case report: 50 years-old-woman, without relevant previous history. She begins to present asthenia, weakness of lower limbs, arthralgias, cramps and appearance of a painfu...

ea0063p622 | Diabetes, Obesity and Metabolism 2 | ECE2019

Assessment of materno-fetal complications in pregnant women with type 1 diabetes exposed to insulin degludec

Martinez Montoro Jose Ignacio , Hernandez Garcia Carmen , Jose Picon Cesar Maria , Molina Vega Maria , Maria Diaz Perdigones Cristina , Damas Fuentes Miguel , Jose Tinahones Madueno Francisco

Introduction: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of adverse outcomes, so pregnancy planning in order to achieve an optimal glycemic control is essential. This control has been made possible, in part, by the widespread use of insulin analogues, especially the long-acting ones, glargine and detemir. Insulin degludec, an ultra-long-acting insulin is not currently approved for pregnant women due to the lack of randomized co...

ea0063p717 | Pituitary and Neuroendocrinology 2 | ECE2019

Glycogenosis and hypofisis pathology, importance of a multidisciplinary management

Cornejo-Pareja Isabel , Maraver-Selfa Silvia , Munoz-Garach Araceli , Gonzalo-Marin Montserrat , Hernandez-Garcia Carmen , Damas-Fuentes Miguel , Mancha-Doblas Isabel , Tinahones Francisco J

Introduction: Glycogenosis is a group of hereditary diseases affecting the glycogen metabolism, due to mutations in enzymes involved in the transformation and synthesis of glucose (liver and muscle glycogenosis). Brain germ tumors are very infrequent. They are located mainly in pineal and sellar region. Central diabetes insipidus is the most frequent manifestation. Their prognosis and response to combined chemo/radiotherapy treatment are favorable.Case r...

ea0049ep614 | Diabetes therapy | ECE2017

New long-acting insulins in type 1 diabetes: implications for real clinical practice

Damas-Fuentes Miguel , Diaz-Perdigones Cristina , Munoz-Garach Araceli , Molina-Vega Maria , Hernandez-Garcia Carmen , Cornejo-Pareja Isabel , Mancha-Doblas Isabel , Tinahones-Madueno Francisco J

The emergence of a new generation of long-acting insulin analogues (insulin degludec -ID- and insulin glargine 300 U/ml -IG300-) has increased treatment options in type 1 diabetes (T1D), demonstrating in clinical trials better metabolic control with lower hypoglycemia rates.Objectives: To assess characteristics of T1D patients who were given ID and IG300 in clinical practice and to evaluate their effect on metabolic control, weight, insulin dose and hypo...

ea0056p16 | Adrenal cortex (to include Cushing's) | ECE2018

Rare incidence of primary adrenocortical carcinosarcoma: a case report

Maria Diaz Perdigones Cristina , Maria Cornejo Pareja Isabel , Damas Fuentes Miguel , Molina Vega Maria , Hernandez Garcia Carmen , Munoz Garach Araceli , Jose Tinahones Madueno Francisco

Introduction: Adrenal tumors are common tumors with a prevalence of around 3% in a population over the age of 50 years. In contrast, adrenocortical carcinoma (ACC) is a rare malignancy (incidence 1–2 per 1 million population) with a heterogeneous presentation and a variable but generally bad prognosis. Patients present with evidence of adrenal steroid hormone excess in approximately 60% of cases.Case report: A 49-year-old woman with symptoms of faci...