Searchable abstracts of presentations at key conferences in endocrinology

ea0063p1102 | Pituitary and Neuroendocrinology 3 | ECE2019

The significance of low TSH value – case report

Vlad Mihaela , Amzar Daniela , Sotanga Lavinia , Toma Andreea

Introduction: Suppression of TSH usually indicates hyperthyroidism. But the etiology of low TSH is very wide, including pituitary pathology. In this report we describe a case diagnosed and treated for hyperthyroidism. Later on, the persistence of suppressed TSH after therapy of hyperthyroidism was due to a GH-secreting pituitary adenoma.Case presentation: A 47-year old woman was referred to our clinic for investigations, due to thyroid pathology. The pat...

ea0049ep153 | Endocrine tumours and neoplasia | ECE2017

Primary hepatic neuroendocrine tumor with multiple liver metastases treated with somatostatin analogues: case report

Golu Ioana , Balas Melania , Amzar Daniela , Cornianu Marioara , Vlad Mihaela

Introduction: Somatostatin analogues (SSA) have been used as first line treatment to control the symtoms in hormonally active neuroendocrine tumors (NET), for over three decades. Primary hepatic neuroendocrine tumors (PHNETs) are rare neoplasms. Despite increased incidence of PHNETs over time, these tumors remain a rarity. According to the previously reported cases, primary neuroendocrine carcinoma of the liver is usually multicentric, often mimicking liver metastases. The dem...

ea0035p893 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Post-partum pituitary insufficiency: diagnostic challenge

Amzar Daniela , Balas Melania , Golu Ioana , Vlad Mihaela , Zosin Ioana

Background: Postpartum hypopituitarism, known as Sheehan’s syndrome, occurs during a complicated childbirth, due to severe hemorrhage and hpovolemic shock that lead to ischemic necrosis of the pituitary gland.The aim of the study is to point out the clinical features in postpartum pituitary necrosis, so that the disease could be recognize rapidly, to present a laboratory work-up for a postive diagnosis, and also to describe the com...

ea0026p293 | Pituitary | ECE2011

Prevalence of sleep apnea sindrome (SAS) in patients with acromegaly

Amzar Daniela , Mihaicuta Stefan , Golu Ioana , Balas Melania , Vlad Mihaela

Sleep apnea syndrome is highly prevalent in acromegaly and only partially reversible after biochemical control of the disease. Consequences of SAS are serious and are associated with increased morbidity and mortality.The present study evaluates clinical aspects in acromegalic patients with sleep apnea syndrome (SAS), diagnosed and followed-up in the Clinic of Endocrinology, Timisoara, in the period 2007–2010. All the cases were confirmed and investi...

ea0022p590 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Sleeping apnea syndrome (SAS) in acromegaly and obesity

Amzar Daniela , Mihaicuta Stefan , Golu Ioana , Balas Melania , Zosin Ioana

The aim of the study: Acromegaly is associated with respiratory and cardiovascular morbidities and high mortality rate. The present study evaluates clinical aspects in acromegalic and obese patients with sleep apnea syndrome (SAS).Material and method: The patients were diagnosed and followed-up in the Clinic of Endocrinology, Timisoara, in the period 2006–2009. All the cases were confirmed and investigated as present guidelines recommend. The polyso...

ea0016p751 | Thyroid | ECE2008

Same aspects regarding immunohistochemical diagnosis of papillary thyroid carcinoma

Zosin Ioana , Golu Ioana , Cornianu Marioara , Amzar Daniela , Balas Melania

The study evaluates the expression of same immunohistochemical (IHC) markers (Ki-67, PCNA, CK-19, HBME-1 and Galectin 3, in the diagnosis of differentiated thyroid carcinomas.Material and methods: The study group comprised 57 patients with thyroid tumors; aged 17–71 years (mean age 48.96 years). All cases were evaluated before surgical treatment by means of clinical examination, thyroid ultrasonography and fine needle aspiration biopsy (FNAB).<p...

ea0081ep823 | Pituitary and Neuroendocrinology | ECE2022

Prevalence of benign and malignant tumors in patients with acromegaly

Plotuna Iulia-Ştefania , Amzar Daniela-Georgiana , Balas Melania , Golu Ioana , Vlad Mihaela

Introduction: Acromegaly is an endocrine disease associated with an abnormal growth-hormone (GH) and insulin-like growth factor 1 (IGF-1) excess. Multiple studies demonstrated an association between these factors and pathways that play a major role in tumor proliferation, survival and resistance to anti-cancer therapies in many human malignancies.Objectives: We wanted to study the incidence and types of tumors which are associated with Acromegaly.<p ...

ea0063p663 | Interdisciplinary Endocrinology 1 | ECE2019

Diagnotic value of Shear Wave Elastography in differentiating parathyroid adenomas from thyroid nodules

Vlad Mihaela , Golu Ioana , Oprea Maria , Amzar Daniela , Balas Melania , Sporea Ioan

Parathyroid adenomas are situated nearby thyroid gland or even intrathyroidal and could be confounded with thyroid nodules. Ultrasound elastography is a noninvasive technique that explores the elasticity and stiffness of different tissue.Aim: To assess the value of 2D-shear wave elastography (2D-SWE), a new technique of sonoelastography, in the differentiation of parathyroid adenomas from thyroid nodules.Subjects and methods: We st...

ea0049gp53 | Cardiovascular &amp; Lipid Endocrinology | ECE2017

Clinical, laboratory and cardiac parameters in overt primary hypothyroidism versus overt central hypothyroidism

Balas Melania , Parv Florina , Vlad Mihaela , Golu Ioana , Amzar Daniela , Zosin Ioana

Background: Hypothyroidism affects cardiac function, leading to cardiomyopathy, pericarditis, lower left ventricular performance, etc. The present study investigates different parameters (clinical, hormonal, biochemical, echocardiographic) in overt primary hypothyroidism (OPHypo) and overt central hypothyroidism (OCHypo).Material and methods: The study included 33 untreated patients with OCHypo (5 with empty sella, 3 with idiopathic hypopituitarism, 7 wi...

ea0049ep306 | Calcium &amp; Vitamin D metabolism | ECE2017

Hyperparathyroidism and cardiovascular risk

Amzar Daniela , Balas Melania , Golu Ioana , Vlad Mihaela , Sandu Ramona , Cornianu Maria

Background: Primary and secondary hyperparathyroidism (HP) are associated with increased risk for cardiovascular complications and high mortality. Risk factors correlated with hypertension in HP are hyperlipidemia, glucose intolerance, insulin resistance, vitamin D deficiency, etc. The aim of the study was to assess the incidence of cardiovascular complications in HP.Material and methods: The study included 45 patients (15 men, 30 women), with a mean age...