Endocrine Abstracts

Acromegaly is a chronic condition associated with an increased risk of cancer.Case presentation: A 41-year-old man admitted to our hospital with gluteal and scapular mass. He had a clinical history of acromegaly which had been diagnosed two years ago, and was treated with trans-sphenoidal surgery. After surgery, although remission was not achieved, he had no doctor visit and control. On physical examination he had typical acromegalic features and there w...

Background: Gaucher disease (GD) is the most prevalent lysosomal disorder caused by GBA mutations and abnormal glucocerebrosidase function, leading to glucocerebroside accumulation mainly in the liver, spleen, bone marrow, lungs, and occasionally in the central nervous system. Gaucher disease type 3c (GD3c) is a rare subtype of the subacute/chronic neuronopathic GD3, caused by homozygosity for the GBA p. Asp448His (D409H) mutation. Case...

Background: Hyperprolactinemia is frequently reported with polycystic ovary syndrome (PCOS). However, there is a controversy whether they share a common mechanism or have cause–result relationship or just are coincidental. The objective of the present study was to identify the cause of hyperprolactinemia in patients with PCOS.Methods: We retrospectively evaluated our outpatient admission records for PCOS, hirsutism, oligomenorrhea, or secondary amen...

Background: and ObjectiveThyroid collision tumors are extremely rare, accounting for just around 1% of all thyroid carcinomas. The objective of this study is to enhance our understanding of the clinical characteristics of these infrequently reported occurrences. In our study, we evaluated the clinical features of medullary thyroid carcinoma (MTC) that existed synchronously with papillary thyroid carcinoma (PTC).Methods: We performed a retrospective anal...

Objective: The study aims to investigate the association between asymptomatic pyuria/bacteriuria at the initiation of SGLT2 inhibitors (SGLT2i) and urinary tract infection (UTI) risk in a cohort of women with type 2 diabetes mellitus (T2DM) (NCT05520684).Methods: The female outpatients with T2DM under follow-up in the department of internal medicine and initiated SGLT2i (dapagliflozin/empagliflozin) were included between February and September 2022. Excl...

Introduction: The main goal of treatment in Cushing’s disease (CD) is to induce remission as well as to restore reproductive function. We aimed to evaluate the reproductive status of the female patients with CD encountered in sexually active patients after surgical with/without medical treatments.Method: The retrospective data was obtained from the medical records of the 72 female patients diagnosed with CD at hospital registration system. The patie...

Subacute Thyroiditis (SAT) is a painful, self-limited inflammation of the thyroid gland. Guidelines recommend Non-Steroid Antiinflammatory Drugs (NSAIDs) for mild cases and steroids for moderate to severe cases. Early relapses can be seen in about 9-35%. The aim of this study was to investigate the clinical, laboratory, and imaging findings that may affect treatment selection and predict relapse.Materials and Methods: Forty SAT patients who applied to th...

Introduction: Non-functional adrenal incidentalomas (AI) are currently quite important since they can also cause metabolic disturbances. This study was designed to evaluate possible insulin resistance indicators and cardiovascular risk factors in patients with non-functional AI.Patients and methods: 83 patients with non-functional AI were enrolled to the study. Control group consisted of 56 patients without any adrenal lesion. Fasting blood glucose, and ...

Introduction: Diabetic foot is one of the important and destructive complications of diabetes. During the life time of a diabetic patient, the risk of developing foot ulcers is around 5–15%, and about 20–25% of the causes of hospitalization in diabetic patients are due to foot ulcers. 40–80% of foot ulcers can be infected and resulted in osteomyelitis. Hospitalization due to osteomyelitis is 12 times more in diabetic patients than in non-diabetic population....

Introduction: Minimally invasive surgery is an alternative surgical approach for primary hyperparathyroidism with less surgical trauma and anesthesia complications. Neck ultrasonography and scintigraphy are still the first step tools for localisating parathyroid lesions. Intact parathyroid hormone (PH) determination in washout samples is really very useful when parathyroid lesions can not be easily distinguished from thyroid lesions or sometimes lymph nodes.<p class="abste...