Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep302 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Effects of glucagon-like peptide 1 analogue on eating behavior in patients with obesity

Logvinova Oksana , Troshina Ekaterina

Introduction: One of the objectives of weight loss in obesity is to prevent metabolic disorders. An important component in the maintenance of the achieved results is a change of eating behavior.Goal: To study the effect of liraglutide 3.0 mg on the dynamics of metabolic parameters and eating behavior in patients with obesity.Materials and methods: The study enrolled 42 obese patients in whom anthropometric parameters, metabolic par...

ea0070aep312 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Combination of baseline body weight with active plasma ghrelin level could predict early response with liraglutide 3.0 mg in patients with obesity

Logvinova Oksana , Troshina Ekaterina

Introduction: Liraglutide 3.0 mg could be effective option for obesity management. It is known that patients who have ≥5% weight loss in 16 weeks (‘early responders’ (ERs)) will have ≥10% weight loss in 56 weeks [1]. Predictors of this early response (ER) in 16 weeks are unknown.Methods: 22 obese patients (30% men; median age 40.0 [33.0; 48.5]) were recruited. The exclusion criteria were diabetes, psychotic disorders, obesity due ...

ea0081ep23 | Adrenal and Cardiovascular Endocrinology | ECE2022

Determination of 18-hydroxycortisol, 18-oxocortisol by HPLC–MS/MS in the differential diagnosis of various forms of primary aldosteronism

Romanova Natalia , Platonova Nadezhda , Troshina Ekaterina

Introduction: Aldosterone synthase participates in the key reactions of aldosterone synthesis – 11-hydroxylation, 18-hydroxylation and, finally, 18-oxidation. In recent works devoted to evaluating the effectiveness of hybrid steroids in the differential diagnosis of subtypes of primary aldosteronism (PA), it is worth emphasizing the experience of using high-performance liquid chromatography – tandem mass spectrometry (HPLC-MS/MS), which allows detecting even very low...

ea0081ep1177 | Late Breaking | ECE2022

Prolonged oral glucose tolerance test in the diagnosis of postprandial non-diabetic hypoglycemia

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina

Introduction: tests alternative to the fasting test are necessary for the diagnosis of numerous causes of non-diabetic hypoglycaemia (NDH), that not provoked by starvation (postprandial hypoglycemia), such as insulin autoimmune syndrome (IAS) and noninsulinoma pancreatogenous hypoglycemia syndrome (NIPHS). However, there is no consensus on the most optimal test (prolonged oral glucose tolerance test (pOGTT) or mixed meal test (MMT)) in this cohort of patients.<p class="abs...

ea0090ep1116 | Late Breaking | ECE2023

Nondiabetic hypoglycemia: the role of psycho-neurological care in primary diagnosis

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina

Introduction: Decreased glycemia in patients without diabetes mellitus (nondiabetic hypoglycemias; NDH) is a manifestation of severe diseases from endocrinopathies to malignant tumors. The most specific symptom of NDH is association of attack with the intake of carbohydrate-containing food. Hypoglycemia is usually manifested by neurological and mental disorders, and therefore, patients initially seek medical help not from an endocrinologist, but from psychiatrists and neurolog...

ea0063p54 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Continuous glucose monitoring during the prolonged fast test for the diagnosis of hypoglycemic diseases: primary data analysis

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina

Introduction: To diagnose the hypoglycemic diseases (HD), firstly, proving the hypoglycemia presence is necessary. For this purpose, the prolonged fast test, which can reach 72 h, is performed. In case of late completion this test has a potential risk of hypoglycemic coma. Repeated glycemia control by glucometer brings discomfort to patients and increases the labor costs of medical workers. In this regard, it was relevant to conduct a study on the comparison of continuous gluc...

ea0063p194 | Diabetes, Obesity and Metabolism 1 | ECE2019

Clinical case of insulin autoimmune syndrome

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina

Introduction: Insulin autoimmune syndrome (IAS) is characterized by the development of hypoglycemia due to insulin and insulin autoantibodies (IAA) interaction. The disease has a strong association with certain alleles of HLA gene. In most cases the disease affects predisposed persons who take drugs containing the sulfhydryl groups. The IAA are also noticed in patients with other autoimmune pathology and in patients with multiple myeloma or monoclonal gammopathy. In c...

ea0056p716 | Clinical case reports - Pituitary/Adrenal | ECE2018

Low-symptomatic PRL-secreting pituitary adenoma in patient with morbid obesity

Logvinova Oksana , Troshina Ekaterina , Mazurina Natal'ya

Introduction: Obesity is one of the most common endocrine disorders. Obesity can either be a symptom of numerous diseases or be associated with them, including cases, when patient does not have other complaints besides excess weight. This should be considered before initiating obesity treatment.Case: A 42-year-old male visited endocrinologist, complaining of overweight. Minimum weight from his adulthood was 70 kg, maximum was for that moment–124.5 k...

ea0073aep193 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Comparative analysis of the methods for differential diagnosis of non-diabetic hypoglycemia (NDH): Beta-hydroxybutyrate and glucagon test

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina

Introductionsome authors propose to conduct consistently two additional tests for differential diagnosis (DD) of NDH with the main purpose to confirm or exclude the autonomous hyperinsulinemia (AH; insulinoma): determination the capillary beta-hydroxybutyrate (BHB) during prolonged fasting test (FT), and glucagon test (GT) at the moment of hypoglycemia. GT is more labor-intensive, high-cost and lead to potential complications. Therefore, we assumed that ...

ea0081ep1000 | Thyroid | ECE2022

Assessment of thyroid function in healthy pregnant women living in iodine deficiency regions

Rybakova Anastasia , Platonova Nadezhda , Nikankina Larisa , Malysheva Natalia , Troshina Ekaterina

Background: During pregnancy, the physiology of the thyroid gland undergoes important changes. As a result, change levels of thyroid hormones. In the latest clinical guidelines, experts have recommended to perform population-based studies to determine reference intervals for thyroid hormones.Aim: To evaluate the reference intervals of free thyroxine in different trimesters of pregnancy in women living in regions with mild iodine deficiency.<p class="...