Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep400 | Developmental endocrinology | ECE2016

Acute exercise training and circulating irisin in adult mens

Arkan Tugba , Calan Mehmet , Celik Aksel , Cimrin Dilek , Bayraktar Firat

Context: Irisin is secreted by skeletal muscles into circulation and proposed to regulate energy homeostasis and hold therapeutic potential in diabetes and obesity.Objective: The aim of this study was to evaluate the effects of acute exercise training (6 week) on circulating plasma irisin in adult mens.Design and setting: This was a cross-sectional study conducted in a university hospital.Participants: A tota...

ea0020p270 | Clinical case reports and clinical reports | ECE2009

Liver manifestation of poorly controlled Type 1 diabetes mellitus: hepatic glycogenosis

Yener Serkan , Ozer Erdener , Yuce Ozlem , Bayraktar Firat , Yesil Sena

We report an 18 years old female with hepatomegaly and elevated liver function tests. She had been diagnosed with Type 1 diabetes mellitus when she was 13 years old. She was referred to our division because of diabetic ketoacidosis. Evaluation of her previous records revealed the presence of liver function abnormalities for 4 months. At physical examination she had an enlarged liver. A1c level was 13%. She was treated initially with intravenous insulin. Following the achieveme...

ea0041ep110 | Bone & Osteoporosis | ECE2016

Clinical characteristics of Paget disease of bone from Turkey

Yavuz Dilek Gogas , Ayturk Semra , Bayraktar Firat , Cetinkalp Sevki , PD Study Group

Prevalence of Paget’s disease (PD) of bone as well as clinical and demographical presentation may differ between the populations.Aim: In this study we evaluate clinical and demographical parameters of Paget’s disease patients followed from endocrinology clinics in Turkey.Method: An invitation was sent to all tertiary endocrinology clinics to complete a survey on demographic clinical, laboratory parameters, treatment modal...

ea0035p370 | Diabetes (epidemiology, pathophysiology) | ECE2014

Compensatory increased irisin levels in gestational diabetes mellitus

Arkan Tugba , Calan Mehmet , Cimrin Dilek , Yesil Pinar , Oktan Mehmet Asi , Aygun Kemal , Bayraktar Firat

Context: Irisin, a newly discovered hormone, is secreted by skeletal muscles into circulation. It is proposed to regulate energy homeostasis and hold therapeutic potential in diabetes and obesity.Objective: We aimed to investigate the association of irisin and uncoupling protein 1 (UCP1) with gestational diabetes mellitus (GDM).Design and Setting: This was a cross-sectional study conducted in a university hospital.<p class="abs...

ea0035p501 | Diabetes therapy | ECE2014

Is there a relationship between body composition and insulin regimen modality in type 1 diabetic patients?

Yilmaz Merve , Gedik Arzu , Yilmaz Simge , Bektas Belgin , Cimrin Dilek , Bayraktar Firat , Demir Tevfik

Introduction: Diabetes is characterized by an increase in abdominal fat. This results in a decrease in lean body mass and increase in insulin resistance. In this study, we aimed to evaluate the possible relationship between body composition and insulin regimen modality in type 1 diabetic patients.Materials and methods: Ninety-two type 1 diabetic patient followed in our institution were included in the study. Patients were classified into two groups accor...

ea0032p904 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Clinical, hormonal and radiological characteristics of a group of primary empty sella patients

Gedik Arzu , Yilmaz Merve , Demir Tevfik , Bayraktar Firat , Men Suleyman , Eraslan Sevinc , Comlekci Abdurrahman

Background: Primary empty sella is an anatomical term defining the herniation of subarachnoid space within the sella turcica without an underlying factor such as pituitary tumor, surgery, irradiation or trauma.Patients and methods: We retrospectively evaluated clinical, hormonal and radiological data of the patients with primary empty sella syndrome followed in our institution between 2001 and 2012.Results: Ninety-four patients (80...

ea0032p912 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Prevalance of cancer in acromegaly patients; a single center data

Gedik Arzu , Yilmaz Merve , Demir Tevfik , Yener Serkan , Bayraktar Firat , Eraslan Sevinc , Comlekci Abdurrahman

Introduction: The growth promoting effects of GH and IGF1 has lead to increasing number of cancer surveillence studies in acromegaly so far. We herein aimed to present the prevalance of cancer in acromegaly patients followed in our institution.Patients and design: We retrospectively analyzed medical records of 151 patients with acromegaly (83 females) followed in our department from 2001 to 2012.Results: Overall, cancer was detecte...

ea0020p32 | Adrenal | ECE2009

Is adrenal adenoma associated with the development of non-alcoholic fatty liver disease?

Yener Serkan , Ertilav Senem , Secil Mustafa , Akinci Baris , Demir Tevfik , Bayraktar Firat , Yesil Sena

It has been previously shown that adrenal adenomas are associated with a variety of metabolic disturbances like glucose intolerance and obesity. The aim of this study is to demonstrate the risk of non-alcoholic fatty liver disease development in subjects with adrenal incidentalomas.Among 302 subjects referred between 2001 and 2008 for the evaluation of incidentally discovered adrenal mass, 150 subjects with appropriate data were included. Computed tomogr...

ea0020p402 | Diabetes and Cardiovascular | ECE2009

C-reactive protein level early after starting standard treatment of diabetic foot infection is associated with amputation risk

Akinci Baris , Yener Serkan , Yesil Sena , Yapar Nur , Kucukyavas Yasin , Comlekci Abdurrahman , Eraslan Sevinc , Bayraktar Firat

Prediction of amputation would aid clinicians in the management of the diabetic foot infections. We aimed to assess the predictability of baseline and early post-treatment levels of acute phase reactants on the outcome of patients with diabetic foot infections.In this study, we included patients with infected diabetic foot ulcers who were hospitalized in Dokuz Eylul University Hospital between January 2003 and January 2008, of which data were collected p...

ea0020p426 | Diabetes and Cardiovascular | ECE2009

The effect of creatinine clearance on the short-term outcome of neuropathic diabetic foot ulcers

Akinci Baris , Yesil Sena , Bayraktar Firat , Kucukyavas Yasin , Yener Serkan , Comlekci Abdurrahman , Eraslan Sevinc

Introduction: Reduced creatinine clearance is related to an increased risk of diabetic foot ulcer development. Wound healing has been reported to be worse in diabetic patients with impaired kidney functions than general diabetic population. This study aimed to investigate the effect of creatinine clearance on the short term outcome of neuropathic diabetic foot ulcers.Materials and methods: Data from 147 neuropathic diabetic foot ulcer episodes were inclu...