Searchable abstracts of presentations at key conferences in endocrinology

ea0063p851 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

True silent pheochromocytoma: description of a rare entity

Adamidou Fotini , Komzia Paraskevi , Mpatsi Ourania , Georgiou Thomas , Kita Marina

Introduction: With the advent of modern imaging, up to 30% of adrenal pheochromocytomas are discovered incidentally in asymptomatic patients. Smaller tumors may be ‘pre-biochemical’ in their secretory capacity, but truly nonfunctioning tumors over 3 cm are exceedingly rare. We describe a case of a clinically and biochemically silent pheochromocytoma.Case report: A 65-year-old woman was found to have a left adrenal incidentaloma on an abdominal ...

ea0063p1163 | Thyroid 3 | ECE2019

Atypical hyperthyroidism in a case of neutrophilic dermatosis (Sweet’s syndrome)

Adamidou Fotini , Komzia Paraskevi , Georgiou Thomas , Kita Marina

Introduction: Sweet’s syndrome is a rare, acute febrile neutrophilic dermatosis, associated with a variety of inflammatory and neoplastic conditions, drug reactions and rarely with a spectrum of thyroid dysfunction. A possible link between thyroid autoimmunity and Sweet’s syndrome has been previously suggested by rare reports of Hashimoto’s thyroiditis, subacute thyroiditis and classic Graves’ disease. We describe a case of ‘atypical’ hyperthyroid...

ea0049ep771 | Clinical case reports - Thyroid/Others | ECE2017

Incidental asplenia in a patient with presumed type 2 autoimmune polyglandular syndrome (APS-2): misclassification or overlap?

Georgiou Thomas , Adamidou Fotini , Mintziori Gesthimani , Kita Marina

Introduction: Asplenia has been reported in 10% of patients with type 1 APS (APS-1), but has never been reported in APS-2. We describe a patient with presumed APS-2 and aplenia.Case report: A 69-year-old woman was diagnosed with B12 deficiency with severe anemia at age 21 and insulin dependent diabetes mellitus at age 33, following routine testing. At 59, she was hospitalized with salt wasting and a diagnosis of Addison’s disease was made, which was...

ea0049ep827 | Thyroid (non-cancer) | ECE2017

Orbital disease primer for Endocrinologists-not always thyroid associated orbitopathy (TAO): a case vignette

Adamidou Fotini , Manani Christina , Anagnostis Panagiotis , Georgiou Thomas , Boboridis Kostas

Background: TAO is a rare disease, seriously involving 5% of patients with autoimmune thyroid disease. The clinical presentation may be difficult to distinguish from other orbital conditions.Case 1: A 63-year-old woman was admitted to the Neurology Service for worsening diplopia over the previous six months, with a working diagnosis of myasthenia gravis or multiple sclerosis. The Endocrine Service was consulted because of a long history of Hashimoto&#146...

ea0056p1071 | Thyroid (non-cancer) | ECE2018

Thyroid autoantibodies and quality of life in patients with benign thyroid diseases

Mintziori Gesthimani , Veneti Stavroula , Panagiotou Athanasios , Georgiou Thomas , Kita Marina

Objective: Thyroid autoimmunity has been proposed as a risk factor for impaired health-related Quality of Life (HRQoL), depression and anxiety, though evidence is still limited. The aim of the current study is to assess the association of thyroid autoimmunity with quality of life in patients with benign thyroid disease.Design: A cross-sectional study was implemented, that included consecutive patients with benign thyroid diseases who visited the outpatie...

ea0063p523 | Calcium and Bone 2 | ECE2019

Relapse of primary hyperparathyroidism concurrent with a plasma cell proliferative disorder: report of a case

Adamidou Fotini , Georgiou Thomas , Daikidou Dimitra , Sarafidis Pantelis , Komzia Paraskevi , Kita Marina

Introduction: Primary hyperparathyroidism associated with multiple myeloma has been rarely reported to coincide, but relapse of previously remitted primary hyperparathyroidism concurrent with a plasma cell proliferative disorder has not been described.Case report: A 76-year-old female was referred to the endocrine clinic for evaluation of primary hyperparathyroidism discovered incidentally during hospitalization for angina. She had a corrected calcium of...

ea0063p889 | Diabetes, Obesity and Metabolism 3 | ECE2019

Radiation-induced loss of glycemic control in a patient with refractory lymphoma

Adamidou Fotini , Komzia Paraskevi , Georgiou Thomas , Tsoutsas Georgios , Panagiotou Athanasios , Kita Marina

Introduction: PD-1 inhibitors are powerful disruptors of self- tolerance and autoimmune diabetes develops in up to 0.9% of patients. Lipodystrophic insulin reactions, although uncommon with human insulin analogs, are a recognized cause of impaired insulin delivery in patients on intensive insulin regimens. We describe a patient with resistant lymphoma and nivolumab-induced autoimmune diabetes, who suffered loss of glycemic control due to early radiation-induced subcutaneous fi...

ea0049ep68 | Adrenal cortex (to include Cushing's) | ECE2017

The role of dehydroepiandrosterone sulphate (DHEAS) in the evaluation of autonomous cortisol secretion in adrenal incidentalomas

Adamidou Fotini , Georgiou Thomas , Mintziori Gesthimani , Tsirou Efrosini , Anagnostis Panagiotis , Panagiotou Athanasios , Kita Marina

Introduction: Subclinical hypercortisolism (SH) has been reported in 5–20% of patients with adrenal incidentalomas (AIs), with various cardiometabolic consequences. We intended to investigate the contribution of DHEAS to standard testing, as another indicator of autonomous cortisol secretion in AIs.Materials and methods: Ninety consecutive patients (n=90) with AIs were included in a prospective cohort study. SH was diagnosed if ≥2 cri...

ea0049ep828 | Thyroid (non-cancer) | ECE2017

Management of very severe Graves’ orbitopathy with low dose rituximab: report of two cases

Adamidou Fotini , Manani Christina , Anagnostis Panagiotis , Georgiou Thomas , Boboridis Kostas , Kita Marina

Introduction: Although Graves’ orbitopathy (GO) is common in the course of Graves’ disease, dysthyroid optic neuropathy and corneal breakdown are rare. We describe two cases of severe GO treated successfully with rituximab.Case 1: A 50-year-old female smoker with Graves’disease, presented with disfiguring eyelid edema, exophthalmos and diplopia, preserved visual acuity and clinical activity score (CAS) ≥ 5. She received pulsed medrox...

ea0049ep1307 | Thyroid (non-cancer) | ECE2017

Thyroid autoimmunity and frequency of malignant or suspicious for malignancy thyroid nodule cytology

Siolos Athanasios , Chambidis Vasileios , Efstathiadou Zoe , Georgiou Thomas , Panagiotou Athanasios , Adamidou Fotini , Kita Marina

Introduction: Thyroid autoimmunity has been associated with the diagnosis of differentiated thyroid (DTC) cancer in surgical series. However, this finding has not been consistent in Fine Needle Aspiration Biopsy (FNAB) cytology series.Aim: We aimed to investigate the association between thyroid autoimmunity and DTC in patients who underwent ultrasound-guided FNAB.Methods: A retrospective analysis of patients who had undergone ultra...