Searchable abstracts of presentations at key conferences in endocrinology

ea0022p845 | Thyroid | ECE2010

Fine needle aspiration biopsy of a thyroid nodule: a comparison of diagnostic performance of experienced and inexperienced physicians

Gursoy Alptekin , Anil Cuneyd , Erismis Betul

Objectives: Ultrasound-guided fine needle aspiration biopsy (US-FNAC) technique has the advantage of obtaining tissue for cytological examination. The diagnostic yield may depend on factors related to both technical aspects and the lesions sampled. However, the variability between experienced and inexperienced physicians in obtaining adequate cytological sample has not been specifically studied previously. The aim of the study was to determine whether there is a difference in ...

ea0022p847 | Thyroid | ECE2010

Prevalence of benign breast diseases in nodular goiter and autoimmune thyroid diseases

Gursoy Alptekin , Guney Tekin , Anil Cuneyd

Objective: The evidence regarding association between thyroid diseases and benign and malign breast diseases is increasing. It has been shown that thyroid disorders are more frequent in those with benign breast diseases and that different thyroid diseases have associations with benign and malign breast diseases and their outcomes. In this study, we aimed to reveal the frequency of benign breast conditions in patients with nodular thyroid disease and Hashimoto’s disease.</...

ea0032p995 | Thyroid (non-cancer) | ECE2013

Metformin decreases thyroid volume and nodule size in subjects with insulin resistance

Gursoy Alptekin , Anil Cuneyd , Atesagaoglu Berna , Kut Altug , Nar Asli , Bascil Tutuncu Neslihan

Introduction: Previous reports have shown that subjects with insulin resistance have increased thyroid volume and nodule prevalence. We investigated the effects of metformin on thyroid volume and nodule size.Methods: This prospective data were gathered on newly diagnosed subjects with insulin resistance (n=100, 68 female, 32 male) between August 2008 and May 2010. Measurements of thyroid hormones and thyroid ultrasonography was performed in all ...

ea0022p852 | Thyroid | ECE2010

Metabolic syndrome and its components are associated with increased thyroid volume and nodule prevalence in a mild-to-moderate iodine deficient area

Ayturk Semra , Gursoy Alptekin , Kut Altug , Anil Cuneyd , Nar Asli , Tutuncu Neslihan Bascil

Objective: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities with insulin resistance (IR) as a major characteristic. It has been recently questioned that MetS and its related components are associated with functional and morphological alterations of thyroid gland. Aim of our study is to examine thyroid volume and nodule prevalence in patients with MetS in a mild-to-moderate iodine deficient area.Design: Two hundred and seventy-eight p...

ea0020p71 | Thyroid | ECE2009

Comparison of the analgesic efficacy of lidocaine/prilocaine (EMLA) cream and needle-free delivery of lidocaine during the fine-needle aspiration biopsy of thyroid nodules

Gursoy Alptekin , Anil Cuneyd , Ayturk Semra , Nar Asli , Tutuncu Neslihan Bascil

Objective: Efficacy of eutectic mixture of local anesthetics (EMLA) cream and the needle-free injection of local anesthesia for reducing the pain associated with fine-needle aspiration biopsy (FNAB) of thyroid nodules was previously reported. However, direct comparison of the analgesic efficacy for both methods has not been established yet. The aim of this study was to compare the analgesic efficacy of EMLA cream and needle-free injection of lidocaine for FNAB-associated pain....

ea0020p143 | Thyroid | ECE2009

Clinical and epidemiological characteristics of thyroid hemiagenesis: ultrasound screening in patients with thyroid disease and normal population

Gursoy Alptekin , Anil Cuneyd , Unal Asli Dogruk , Nar Asli , Tutuncu Neslihan Bascil , Erdogan Murat Faik

Objective: Thyroid hemiagenesis is a rare form of thyroid dysgenesis, in which one thyroid lobe fails to develop. The true prevalence of this rare abnormality is about 0.05–0.2% in normal population. We aimed to determine prevalence of thyroid hemiagenesis in patients with various thyroid disorders and a normal population in a mild to moderate iodine-deficient area.Subjects and methods: The clinical and thyroid ultrasonography records of 4.833 patie...

ea0020p378 | Diabetes and Cardiovascular | ECE2009

The effect of glycemic control on mean platelet volume in patients with type 2 diabetes mellitus

Gursoy Alptekin , Anil Cuneyd , Ayturk Semra , Nar Asli , Tutuncu Neslihan Bascil

Objective: Morphologic and functional platelet abnormalities have been previously reported in patients with type 2 diabetes mellitus (DM) and some of these abnormalities have been linked to increased cardiovascular risk. Mean platelet volume (MPV) informs not only about platelet size, but also about its functions. Larger platelets bear more thrombotic potential. Higher MPV values have been correlated with cardiovascular events in the short and long run. Previous studies have d...

ea0016p113 | Clinical cases | ECE2008

Unresectable huge sternal and mediastinal metastasis of follicular thyroid carcinoma; radiotherapy as first-line and palliative therapy

Demirer Asli Nar , Ayturk Semra , Tutuncu Neslihan Bascil , Gursoy Alptekin , Pak Yucel , Demirag Nilgun Guvener

Distant metastases as initial manifestation of follicular thyroid carcinoma is rare. We report a case of an unusual initial presentation of follicular thyroid carcinoma on follow-up. A 52-year-old woman presented with a 12-month history of progressively enlarging mass in the anterior chest wall. The mass was fixed to the chest wall, measuring 12×10 cm in diameter. Computed tomography demonstrated a lobulated soft-tissue mass (17×11×6 cm) destructing sternum and ...

ea0016p684 | Thyroid | ECE2008

Anti-BIP levels on Hashimoto's thyroiditis

Asik Mehmet , Sahin Mustafa , Arikan Serap , Gursoy Alptekin , Ayturk Semra , Bakiner Okan , Tutuncu Neslihan Bascil

To asses the presence of antibodies to BIP/GRP78, which is a chaperon of endoplasmic reticulum and has immune modulating and antiapoptotic effects in Hashimoto’s thyroiditis.The study included 62 patients with autoimmune thyroiditis. Of these, 20 had euthyroid, 27 had subclinical hypothyroid, and 15 had hypothyroid Hashimato’s thyroiditis. A control group including 37 healthy patients also participated in the study.There ...

ea0016p690 | Thyroid | ECE2008

Clinicopathological characteristics of thyroid cancer in patients on dialysis for end-stage renal disease

Demirer Asli Nar , Kemal Yasemin , Tutuncu Neslihan Bascil , Gursoy Alptekin , Demirag Nilgun Guvener

Objective: Our aim was to determine the prevalence and clinicopathological characteristics of thyroid cancers in the dialysis population and to evaluate potential risk factors.Design: We performed a retrospective analysis of our end-stage renal disease (ESRD) patients on dialysis and thyroidectomized patients without ESRD (2000–2006). Then we compared the data of thyroid cancer patients on dialysis (n=9) with the data of patients who had hist...